Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Cell fitness"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
γδT17 cells are a subset of γδT cells producing IL-17, which is crucial for protection against bacterial and fungal infections. It has recently been shown that γδT17 cells have enriched lipid storage and lipid metabolism. However, the regulatio
Externí odkaz:
https://doaj.org/article/497b3e2e12c2463e9dc9f384dc5bea98
Autor:
Wendy Mao
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The antitumor potential of personalized immunotherapy, including adoptive T-cell therapy, has been shown in both preclinical and clinical studies. Combining cell therapy with targeted metabolic interventions can further enhance therapeutic outcomes i
Externí odkaz:
https://doaj.org/article/7e5b934031b246468db1a2e7ad360cd6
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 10, Pp 1029-1036 (2021)
Complex multicellular organisms require quantitative and qualitative assessments on each of their constitutive cell types to ensure coordinated and cooperative behavior towards overall functional proficiency. Cell competition represents one of the op
Externí odkaz:
https://doaj.org/article/318942ad30a943f2af76f12e08532d11
Autor:
Michail Yekelchyk, Esha Madan, Jochen Wilhelm, Kirsty R Short, António M Palma, Linbu Liao, Denise Camacho, Everlyne Nkadori, Michael T Winters, Emily S Rice, Inês Rolim, Raquel Cruz‐Duarte, Christopher J Pelham, Masaki Nagane, Kartik Gupta, Sahil Chaudhary, Thomas Braun, Raghavendra Pillappa, Mark S Parker, Thomas Menter, Matthias Matter, Jasmin Dionne Haslbauer, Markus Tolnay, Kornelia D Galior, Kristina A Matkwoskyj, Stephanie M McGregor, Laura K Muller, Emad A Rakha, Antonio Lopez‐Beltran, Ronny Drapkin, Maximilian Ackermann, Paul B Fisher, Steven R Grossman, Andrew K Godwin, Arutha Kulasinghe, Ivan Martinez, Clay B Marsh, Benjamin Tang, Max S Wicha, Kyoung Jae Won, Alexandar Tzankov, Eduardo Moreno, Rajan Gogna
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 11, Pp 1-17 (2021)
Abstract Risk stratification of COVID‐19 patients is essential for pandemic management. Changes in the cell fitness marker, hFwe‐Lose, can precede the host immune response to infection, potentially making such a biomarker an earlier triage tool.
Externí odkaz:
https://doaj.org/article/f8eb078fb27a469bb4350f69d131fd6a
Autor:
Alina Hagen, Sabine Niebert, Vivian-Pascal Brandt, Heidrun Holland, Michaela Melzer, Axel Wehrend, Janina Burk
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Successful translation of multipotent mesenchymal stromal cell (MSC)-based therapies into clinical reality relies on adequate cell production procedures. These should be available not only for human MSC, but also for MSC from animal species relevant
Externí odkaz:
https://doaj.org/article/d1898e3e8f97462caa2c23ae775bb14c
Autor:
Hagen, Alina, Holland, Heidrun, Brandt, Vivian-Pascal, Doll, Carla U., Häußler, Thomas C., Melzer, Michaela, Moellerberndt, Julia, Lehmann, Hendrik, Burk, Janina
Simple Summary Regenerative medicine using platelet-based blood products or adult stem cells offers the prospect of better clinical outcomes with many diseases. In veterinary medicine, most progress has been made with the development and therapeutic
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A85694
https://ul.qucosa.de/api/qucosa%3A85694/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A85694/attachment/ATT-0/
Autor:
Hagen, Alina, Niebert, Sabine, Brandt, Vivian-Pascal, Holland, Heidrun, Melzer, Michaela, Wehrend, Axel, Burk, Janina
Successful translation of multipotent mesenchymal stromal cell (MSC)-based therapies into clinical reality relies on adequate cell production procedures. These should be available not only for human MSC, but also for MSC from animal species relevant
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A87871
https://ul.qucosa.de/api/qucosa%3A87871/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A87871/attachment/ATT-0/
Akademický článek
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Autor:
Palak H. Mehta, Salvatore Fiorenza, Rachel M. Koldej, Anthony Jaworowski, David S. Ritchie, Kylie M. Quinn
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
A range of emerging therapeutic approaches for the treatment of cancer aim to induce or augment endogenous T cell responses. Chimeric antigen receptor (CAR) T cell therapy (CTT) is one such approach that utilises the patient’s own T cells, engineer
Externí odkaz:
https://doaj.org/article/aadff898576844feb5cfd0a605822392
Autor:
Natalia Sanchez de Groot, Marc Torrent Burgas, Charles NJ Ravarani, Ala Trusina, Salvador Ventura, M Madan Babu
Publikováno v:
Molecular Systems Biology, Vol 15, Iss 4, Pp 1-20 (2019)
Abstract Phase separation of soluble proteins into insoluble deposits is associated with numerous diseases. However, protein deposits can also function as membrane‐less compartments for many cellular processes. What are the fitness costs and benefi
Externí odkaz:
https://doaj.org/article/d4c0cd8793f240388d4a61302f5060a5