Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Cell death and immune response"'
Autor:
Jiwoong Choi, Il Seong Lee, Ju Seung Lee, Sangmin Jeon, Wan Su Yun, Suah Yang, Yujeong Moon, Jinseong Kim, Jeongrae Kim, Seunghwan Choy, Chanho Jeong, Man Kyu Shim, Tae-il Kim, Kwangmeyung Kim
Publikováno v:
Biomaterials Research, Vol 26, Iss 1, Pp 1-15 (2022)
Abstract Background Photodynamic therapy (PDT) is a promising strategy to promote antitumor immunity by inducing immunogenic cell death (ICD) in tumor cells. However, practical PDT uses an intense visible light owing to the shallow penetration depth
Externí odkaz:
https://doaj.org/article/f822eaeb606a4b07958a4d9d9f53909a
Autor:
Anna Krone, Yan Fu, Simon Schreiber, Johanna Kotrba, Loisa Borde, Aileen Nötzold, Christoph Thurm, Jonas Negele, Tobias Franz, Sabine Stegemann-Koniszewski, Jens Schreiber, Christoph Garbers, Aniruddh Shukla, Robert Geffers, Burkhart Schraven, Dirk Reinhold, Anne Dudeck, Annegret Reinhold, Andreas J. Müller, Sascha Kahlfuss
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Scientific Reports
Scientific Reports
T helper (Th) cells provide immunity to pathogens but also contribute to detrimental immune responses during allergy and autoimmunity. Th2 cells mediate asthmatic airway inflammation and Th1 cells are involved in the pathogenesis of multiple sclerosi
Autor:
Kamiya, Mari, Mizoguchi, Fumitaka, Kawahata, Kimito, Wang, Dengli, Nishibori, Masahiro, Day, Jessica, Louis, Cynthia, Wicks, Ian P., Kohsaka, Hitoshi, Yasuda, Shinsuke
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Nature Communications
Nature Communications
Muscle cell death in polymyositis is induced by CD8+ cytotoxic T lymphocytes. We hypothesized that the injured muscle fibers release pro-inflammatory molecules, which would further accelerate CD8+ cytotoxic T lymphocytes-induced muscle injury, and in
Autor:
Natalie Lisa Payne, Assifa Hisana, Di Zheng, Daniel H.D. Gray, Georgia Wallis, David R. Powell, Tracy Heng, J. D'Rozario, David C.S. Huang, Swee Heng Milon Pang, Senora Mendonca, Tejasvini Bhuvan, Grant Dewson, Adele Barugahare, Jai Rautela, Nicholas D. Huntington
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Nature Communications
Multipotent mesenchymal stromal cells (MSCs) ameliorate a wide range of diseases in preclinical models, but the lack of clarity around their mechanisms of action has impeded their clinical utility. The therapeutic effects of MSCs are often attributed
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-13 (2021)
Cell Death & Disease
Cell Death & Disease
Tumor necrosis factor (TNF)-α-induced protein 8-like 2 (TIPE2) is a newly discovered negative immunoregulatory protein that is involved in various cellular immune responses to infections. However, the underlying mechanism by which TIPE2 affects the
Autor:
Jan Rybniker, Hannah S. Eisfeld, Melanie Fritsch, Manolis Pasparakis, Sebastian J. Theobald, Sandra Winter, Jessica Gräb, Maximilian Koch, Hamid Kashkar, Christoph Hölscher, Isabelle Suárez
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-14 (2021)
Cell Death Discovery
Cell Death Discovery
Necrotic cell death represents a major pathogenic mechanism of Mycobacterium tuberculosis (Mtb) infection. It is increasingly evident that Mtb induces several types of regulated necrosis but how these are interconnected and linked to the release of p
Autor:
Jonathan C. Kagan, Dania Zhivaki
Publikováno v:
Nature Reviews. Immunology
Oxidized phospholipids that result from tissue injury operate as immunomodulatory signals that, depending on the context, lead to proinflammatory or anti-inflammatory responses. In this Perspective, we posit that cells of the innate immune system use
Autor:
Huan Dou, Jun Liang, Jingman Li, Wei Kong, Li Lu, Yuchen Pan, Jiali Wang, Xiaoyu Xia, Dan Li, Yayi Hou, Tingting Wang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-14 (2021)
Cell Death & Disease
Cell Death & Disease
Recent studies indicate that Toll-like receptors (TLRs) and C-type lectin receptors (CLRs) can function as the signal of pattern recognition receptors, which play a pivotal role in the pathogenesis of the autoimmune disease. Systemic lupus erythemato
Autor:
Jinxiu Rui, Tomokazu Sumida, Kevan C. Herold, Maya Levine-Ritterman, Nathan Lawlor, Michael L. Stitzel, Romy Kursawe, Gerald Ponath, Ana Luisa Perdigoto, Songyan Deng, Jun Lu, David Pitt
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
β cells may participate and contribute to their own demise during Type 1 diabetes (T1D). Here we report a role of their expression of Tet2 in regulating immune killing. Tet2 is induced in murine and human β cells with inflammation but its expressio
Publikováno v:
Laboratory Investigation; a Journal of Technical Methods and Pathology
Immune cells are involved in skeletal muscle regeneration. The mechanism by which Treg cells are involved in the regeneration of injured skeletal muscle is still unclear. The purpose of this study was to explore the role of programmed death-1 in cont