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pro vyhledávání: '"Cell adhesion molecule 2"'
Akademický článek
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Autor:
Dongliang Li, Yongjian Zhang, He Zhang, Chao Zhan, Xin Li, Tu Ba, Zini Qiu, Fang E, Guixiang Lv, Chendan Zou, Chuxuan Wang, Lining Si, Chaoxia Zou, Qiang Li, Xu Gao
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-11 (2018)
Abstract Background Cell adhesion molecules (CADMs) comprise of a protein family whose functions include maintenance of cell polarity and tumor suppression. Hypo-expression of CADM2 gene expression has been observed in several cancers including hepat
Externí odkaz:
https://doaj.org/article/a71d22f771f04ec88e66f35748f9a212
Autor:
Thorpe, Hayley
Genome-wide association studies identify Cell Adhesion Molecule 2 (CADM2) as a candidate risk gene for lifetime cannabis use and posit its involvement in neurobiological processes that overlap with cannabinoid activity. However, CADM2 polymorphisms a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______453::fd7dc93b1beaaceb4b2154d6dd0a7e46
https://hdl.handle.net/10214/27608
https://hdl.handle.net/10214/27608
Autor:
Lu Dai, Concetta Elisa Onesti, Ying-Ying Liang, Alfredo Addeo, Hui-Dong Long, Gang Chen, Pieter E. Postmus, Jun Yin, Zhi-Wei Liao, Yi-Hua Li, Justin D. Blasberg, Xu-Guang Rao, Jian Zhao
Publikováno v:
J Thorac Dis
Journal of Thoracic Disease, 13(4), 2437-2446. AME PUBL CO
Journal of Thoracic Disease, 13(4), 2437-2446. AME PUBL CO
BACKGROUND: Lung cancer is one kind of malignant tumor with a high risk for morbidity and mortality compared to other solid organ malignancies. Brain metastases occur in 30–55% of non-small cell lung cancer (NSCLC) patients. Prognosis of NSCLC pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f77e47d0a80cab1bacb67b81e69ff200
https://hdl.handle.net/1887/3276397
https://hdl.handle.net/1887/3276397
Publikováno v:
Journal of International Medical Research, Vol 48 (2020)
The Journal of International Medical Research
The Journal of International Medical Research
Objective To observe the effects of glutaminase (GLS) inhibitors on autophagy and proliferation of pancreatic stellate cells, and to explore their functions in pancreatic cancer. Methods Pancreatic cancer cells were divided into two groups. Group A w
Publikováno v:
Translational Oncology
Translational Oncology, Vol 14, Iss 7, Pp 101096-(2021)
Translational Oncology, Vol 14, Iss 7, Pp 101096-(2021)
Highlights • FOXO3a was down-regulated and TWIST-1 was up-regulated in breast cancer tissues. • Overexpression of FOXO3a suppressed the EMT and metastasis of breast cancer. • Knockdown of TWIST-1 inhibited the EMT and metastasis of breast cance
Autor:
Ricardo Viais, Jens Lüders, Joana Figueiro-Silva, Bartolomeu Perelló-Amorós, Alba Ortega-Gascó, Lluís Pujadas, Ramon Trullas, Eduardo Soriano, Antoni Parcerisas, Anna La Torre, Sergi Simó, Keiko Hino
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cereb Cortex
instname
Cereb Cortex
Neural cell adhesion molecule 2 (NCAM2) is involved in the development and plasticity of the olfactory system. Genetic data have implicated the NCAM2 gene in neurodevelopmental disorders including Down syndrome and autism, although its role in cortic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88914b2787e4fb39b7a5a1a160949d83
http://hdl.handle.net/10261/224049
http://hdl.handle.net/10261/224049
Publikováno v:
Cerebral Cortex. 29:1439-1459
The neural cell adhesion molecule 2 (NCAM2) is encoded by a gene on chromosome 21 in humans. NCAM2 accumulates in synapses, but its role in regulation of synapse formation remains poorly understood. We demonstrate that an increase in NCAM2 levels res
Publikováno v:
The Journal of Biological Chemistry
Neural cell adhesion molecules 1 (NCAM1) and 2 (NCAM2) belong to the cell adhesion molecules of the immunoglobulin superfamily and have been shown to regulate formation, maturation, and maintenance of synapses. NCAM1 and NCAM2 undergo proteolysis, bu
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 10021, p 10021 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 10021, p 10021 (2021)
Although it has been over 20 years since Neural Cell Adhesion Molecule 2 (NCAM2) was identified as the second member of the NCAM family with a high expression in the nervous system, the knowledge of NCAM2 is still eclipsed by NCAM1. The first studies