Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Cell Survival/genetics"'
Autor:
Poria, D., Sun, C., Santeford, A., Kielar, M., Apte, R.S., Kisselev, O.G., Chen, S., Kefalov, V.J.
Publikováno v:
Scientific reports, vol 12, iss 1
Scientific reports, vol. 12, no. 1, pp. 2897
Scientific reports, vol. 12, no. 1, pp. 2897
Calcium regulates the response sensitivity, kinetics and adaptation in photoreceptors. In striped bass cones, this calcium feedback includes direct modulation of the transduction cyclic nucleotide-gated (CNG) channels by the calcium-binding protein C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e0dd641a8342c457f6f7d87ab8da47
https://doi.org/10.1038/s41598-022-06571-3
https://doi.org/10.1038/s41598-022-06571-3
Autor:
Nicolas Degauque, Claire Soulard, Frédérique Scamps, David Laplaud, Attila Gergely Végh, Céline Salsac, Margot Libralato, Cédric Raoul, Emmanuelle Coque, Stéphanie Ventéo, Csilla Gergely, José Boucraut, Gabriel Espinosa-Carrasco, Roxane Crabé, Béla Varga, Alexandre Brodovitch, Thierry Vincent, Anaïs Virenque, Javier Hernandez, Julie K. Fierle, Marion Cadoux
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (6), pp.2312-2317. ⟨10.1073/pnas.1815961116⟩
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (6), pp.2312-2317. ⟨10.1073/pnas.1815961116⟩
Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 6, pp. 2312-2317
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (6), pp.2312-2317. ⟨10.1073/pnas.1815961116⟩
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (6), pp.2312-2317. ⟨10.1073/pnas.1815961116⟩
Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 6, pp. 2312-2317
Adaptive immune response is part of the dynamic changes that accompany motoneuron loss in amyotrophic lateral sclerosis (ALS). CD4 + T cells that regulate a protective immunity during the neurodegenerative process have received the most attention. CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b74d69287c1970bf57c427665e4698
https://www.hal.inserm.fr/inserm-03171288
https://www.hal.inserm.fr/inserm-03171288
Autor:
Giuseppe Vassalli, Giovanni G. Camici, Sara Bolis, Elisabetta Cervio, Giuseppina Milano, Vanessa Biemmi, A. Ciullo, Tiziano Moccetti, Emanuel T. Fertig, Lucio Barile, Mihaela Gherghiceanu
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 3, p 468 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 3
International journal of molecular sciences, vol. 20, no. 3
International Journal of Molecular Sciences
Volume 20
Issue 3
International journal of molecular sciences, vol. 20, no. 3
Cell therapy has been evaluated to enhance heart function after injury. Delivered cells mostly act via paracrine mechanisms, including secreted growth factors, cytokines, and vesicles, such as exosomes (Exo). Intramyocardial injection of cardiac-resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd80ce773ca01cb03b66b6207e52de7
https://www.mdpi.com/1422-0067/20/3/468
https://www.mdpi.com/1422-0067/20/3/468
Autor:
Dario Motti, Roberta Brambilla, Pernille M. Madsen, John R. Bethea, Shaffiat Karmally, Kate Lykke Lambertsen, David E. Szymkowski
Publikováno v:
Madsen, P M, Motti, D, Karmally, S, Szymkoski, D E, Lambertsen, K L, Bethea, J R & Brambilla, R 2016, ' Oligodendroglial TNFR2 mediates membrane TNF-dependent repair in experimental autoimmune encephalomyelitis by promoting oligodendrocyte differentiation and remyelination ', The Journal of Neuroscience, vol. 36, no. 18, pp. 5128-5143 . https://doi.org/10.1523/JNEUROSCI.0211-16.2016
Tumor necrosis factor (TNF) is associated with the pathophysiology of various neurological disorders, including multiple sclerosis. It exists as a transmembrane form tmTNF, signaling via TNF receptor 2 (TNFR2) and TNFR1, and a soluble form, solTNF, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8283251c51da24ebaa5d9836fbe02c9
https://doi.org/10.1523/jneurosci.0211-16.2016
https://doi.org/10.1523/jneurosci.0211-16.2016
Autor:
Taiping Chen, John H. Richburg, Sharon Y.R. Dent, Raif S. Geha, Jean Louis Guénet, Caitlin J. Murphy, Carlos J. Perez, Janet Chou, Jean Jaubert, Tewfik Hamidi, Meichun Deng, Craig D. Platt, Qinghua Shi, Yue Lu, Héctor Gaitán-Peñas, Fernando Benavides, Kevin Lin, Jeesun Kim, Hui Lin Pan, Mark T. Bedford, Jianqiang Bao, Meng Hua Zhou, Huan Zhang, Yuying Huang, Raúl Estévez
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
JCI Insight
JCI Insight, American Society for Clinical Investigation, 2018, 3 (16), pp.e99767. ⟨10.1172/jci.insight.99767⟩
JCI Insight, 2018, 3 (16), pp.e99767. ⟨10.1172/jci.insight.99767⟩
Universidad de Barcelona
JCI Insight
JCI Insight, American Society for Clinical Investigation, 2018, 3 (16), pp.e99767. ⟨10.1172/jci.insight.99767⟩
JCI Insight, 2018, 3 (16), pp.e99767. ⟨10.1172/jci.insight.99767⟩
International audience; Ion channel-controlled cell volume regulation is of fundamental significance to the physiological function of sperm. In addition to volume regulation, LRRC8A-dependent volume-regulated anion channel (VRAC) activity is involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb59899d04360969f84ccb27e341fc46
http://hdl.handle.net/2445/172306
http://hdl.handle.net/2445/172306
Autor:
Eline Menu, Els Van Valckenborgh, Nathan De Beule, Karin Vanderkerken, Hendrik De Raeve, Helena Eriksson, Alboukadel Kassambara, Ken Maes, Elke De Bruyne, Karel Fostier, Roy Heusschen, Dirk Hose, Jérôme Moreaux, Kim De Veirman
Publikováno v:
Cancer immunology research. 5(10)
Dysregulated expression of S100 protein family members is associated with cancer proliferation, invasion, angiogenesis, and inflammation. S100A9 induces myeloid-derived suppressor cell (MDSC) accumulation and activity. MDSCs, immunosuppressive cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8286b00699d03648115eccc4a164f7
https://pubmed.ncbi.nlm.nih.gov/28903971
https://pubmed.ncbi.nlm.nih.gov/28903971
Autor:
Olivier Demaria, Léa Zaffalon, Michel Gilliet, Rébecca Panes, Alexey G. Ryazanov, Fabio Martinon, Aude De Gassart
Publikováno v:
EMBO reports, vol. 17, no. 10, pp. 1471-1484
Activation of the elongation factor 2 kinase (eEF2K) leads to the phosphorylation and inhibition of the elongation factor eEF2, reducing mRNA translation rates. Emerging evidence indicates that the regulation of factors involved in protein synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb1e85c9b60bac9cf1a20ef3278146d
https://pubmed.ncbi.nlm.nih.gov/27572820
https://pubmed.ncbi.nlm.nih.gov/27572820
Autor:
Simon M. G. Braun, Francesca Milanesi, Geoffrey M. Wahl, Luo Wei Rodewald, Anand Matani, Mark Wade, Yao-Cheng Li
Publikováno v:
Oncogene
Oncogene, Vol. 31, No 45 (2012) pp. 4789-4797
Oncogene, Vol. 31, No 45 (2012) pp. 4789-4797
Mdm2 is the major negative regulator of p53 tumor-suppressor activity. This oncoprotein is overexpressed in many human tumors that retain the wild-type p53 allele. As such, targeted inhibition of Mdm2 is being considered as a therapeutic anticancer s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d33113f939ca43c419f8f358a88781
http://europepmc.org/articles/PMC3337965
http://europepmc.org/articles/PMC3337965
Publikováno v:
Koulnis, M, Porpiglia, E, Hidalgo, D & Socolovsky, M 2014, ' Erythropoiesis : from molecular pathways to system properties ', Advances in Experimental Medicine and Biology, vol. 844, pp. 37-58 . https://doi.org/10.1007/978-1-4939-2095-2_3
Erythropoiesis is regulated through a long-range negative feedback loop, whereby tissue hypoxia stimulates erythropoietin (Epo) secretion, which promotes an increase in erythropoietic rate. However, this long-range feedback loop, by itself, cannot ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pure_au_____::2c9a673058d73746f0848b2fee801a25
https://pure.au.dk/portal/da/publications/erythropoiesis(f8992aab-7e1f-48f4-bd35-8ec6a5dc7436).html
https://pure.au.dk/portal/da/publications/erythropoiesis(f8992aab-7e1f-48f4-bd35-8ec6a5dc7436).html
Autor:
Christian, Garm, Maria, Moreno-Villanueva, Alexander, Bürkle, Lisbeth Aagaard, Larsen, Vilhelm A, Bohr, Kaare, Christensen, Tinna, Stevnsner
Publikováno v:
Garm, C, Moreno-Villanueva, M, Bürkle, A, Larsen, L A, Bohr, V, Christensen, K & Stevnsner, T V 2013, ' Genetic and environmental influence on DNA strand break repair : A twin study ', Environmental and Molecular Mutagenesis. Supplement, vol. 54, no. 6, pp. 414-420 . https://doi.org/10.1002/em.21791
Garm, C, Moreno-Villanueva, M, Bürkle, A, Larsen, L A, Bohr, V A, Christensen, K & Stevnsner, T V 2013, ' Genetic and environmental influence on DNA strand break repair: a twin study ', Environmental and Molecular Mutagenesis, vol. 54, no. 6, pp. 414-420 . https://doi.org/10.1002/em.21791
Garm, C, Moreno-Villanueva, M, Bürkle, A, Larsen, L A, Bohr, V A, Christensen, K & Stevnsner, T V 2013, ' Genetic and environmental influence on DNA strand break repair: a twin study ', Environmental and Molecular Mutagenesis, vol. 54, no. 6, pp. 414-420 . https://doi.org/10.1002/em.21791
Accumulation of DNA damage deriving from exogenous and endogenous sources has significant consequences for cellular survival, and is implicated in aging, cancer, and neurological diseases. Different DNA repair pathways have evolved in order to mainta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::29f4aa833d5aa1d2e714ca0d4bd7bc66
https://portal.findresearcher.sdu.dk/da/publications/d4a7fa65-cf43-4436-bcce-4317c39170d7
https://portal.findresearcher.sdu.dk/da/publications/d4a7fa65-cf43-4436-bcce-4317c39170d7