Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Cell Respiration/drug effects"'
Autor:
Diederik W. D. Kuster, Michel van Weeghel, Vida Alizadeh Tazehkandi, Luciënne Baks-Te Bulte, Gustav J. Strijkers, Bram F. Coolen, Ntsiki M. Held, Bianca J. J. M. Brundel, Riekelt H. Houtkooper, Mariah R R Daal, Marit Wiersma, Rob C. I. Wüst
Publikováno v:
Wüst, R C I, Coolen, B F, Held, N M, Daal, M R R, Tazehkandi, V A, Baks-Te Bulte, L, Wiersma, M, Kuster, D W D, Brundel, B J J M, van Weeghel, M, Strijkers, G J & Houtkooper, R H 2021, ' The antibiotic doxycycline impairs cardiac mitochondrial and contractile function ', International Journal of Molecular Sciences, vol. 22, no. 8, 4100 . https://doi.org/10.3390/ijms22084100
International journal of molecular sciences, 22(8):4100. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, 22(8):4100, 1-19. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences
Volume 22
Issue 8
Wüst, R C I, Coolen, B F, Held, N M, Daal, M R R, Tazehkandi, V A, Baks-Te Bulte, L, Wiersma, M, Kuster, D W D, Brundel, B J J M, van Weeghel, M, Strijkers, G J & Houtkooper, R H 2021, ' The antibiotic doxycycline impairs cardiac mitochondrial and contractile function ', International Journal of Molecular Sciences, vol. 22, no. 8, 4100, pp. 1-19 . https://doi.org/10.3390/ijms22084100
International Journal of Molecular Sciences, 22(8):4100. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, Vol 22, Iss 4100, p 4100 (2021)
International journal of molecular sciences, 22(8):4100. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, 22(8):4100, 1-19. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences
Volume 22
Issue 8
Wüst, R C I, Coolen, B F, Held, N M, Daal, M R R, Tazehkandi, V A, Baks-Te Bulte, L, Wiersma, M, Kuster, D W D, Brundel, B J J M, van Weeghel, M, Strijkers, G J & Houtkooper, R H 2021, ' The antibiotic doxycycline impairs cardiac mitochondrial and contractile function ', International Journal of Molecular Sciences, vol. 22, no. 8, 4100, pp. 1-19 . https://doi.org/10.3390/ijms22084100
International Journal of Molecular Sciences, 22(8):4100. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, Vol 22, Iss 4100, p 4100 (2021)
Tetracycline antibiotics act by inhibiting bacterial protein translation. Given the bacterial ancestry of mitochondria, we tested the hypothesis that doxycycline—which belongs to the tetracycline class—reduces mitochondrial function, and results
Autor:
Maren Lindner, Béatrice Pignolet, David Brassat, Petra Hundehege, Maria Eveslage, Melanie Eschborn, Johanna Breuer, Luisa Klotz, Karin Loser, Andreas Schulte-Mecklenbeck, Sven G. Meuth, Judith Austermann, Catharina C. Gross, Nicole Freise, Karin B. Busch, Nicholas Schwab, Giulia Nebel, Tilman Schneider-Hohendorf, Timothy J. Turner, Vilmos Posevitz, Heinz Wiendl, Marie Liebmann, Amit Bar-Or, Martin Herold, Shirin Glander, Belén Torres Garrido, Johannes Roth, Claudia Janoschka, Timo Wirth, Graham R. Campbell, Don J. Mahad, Monika Stoll
Publikováno v:
Klotz, L, Eschborn, M, Lindner, M, Liebmann, M, Herold, M, Janoschka, C, Torres Garrido, B, Schulte-Mecklenbeck, A, Gross, C C, Breuer, J, Hundehege, P, Posevitz, V, Pignolet, B, Nebel, G, Glander, S, Freise, N, Austermann, J, Wirth, T, Campbell, G R, Schneider-Hohendorf, T, Eveslage, M, Brassat, D, Schwab, N, Loser, K, Roth, J, Busch, K B, Stoll, M, Mahad, D J, Meuth, S G, Turner, T, Bar-Or, A & Wiendl, H 2019, ' Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects ', Science Translational Medicine, vol. 11, no. 490, eaao5563 . https://doi.org/10.1126/scitranslmed.aao5563
Science Translational Medicine, 11(490):5563. American Association for the Advancement of Science
Science Translational Medicine
Science Translational Medicine, 2019, 11 (490), ⟨10.1126/scitranslmed.aao5563⟩
Science Translational Medicine, 11(490):5563. American Association for the Advancement of Science
Science Translational Medicine
Science Translational Medicine, 2019, 11 (490), ⟨10.1126/scitranslmed.aao5563⟩
International audience; Interference with immune cell proliferation represents a successful treatment strategy in T cell-mediated autoimmune diseases such as rheumatoid arthritis and multiple sclerosis (MS). One prominent example is pharmacological i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c6a6928d973af7c45bf548e65e0113
https://hdl.handle.net/20.500.11820/c76c0dcd-4614-4fdc-92e3-04332843a83f
https://hdl.handle.net/20.500.11820/c76c0dcd-4614-4fdc-92e3-04332843a83f
Autor:
Geerte Hoeke, Anne Reifel Miller, Patrick C.N. Rensen, Lea H. Dib, Bharat Shimpukade, Trond Ulven, Tamer Coskun, Anthony Okolo, Sander Kooijman, Maaike Schilperoort, Natarin Caengprasath, Mark Christian, Yi-Wah Chan, Aylin C. Hanyaloglu, Andrea D. van Dam, Sami Damak, Isabel M. Mol, Irina G. Shabalina
Publikováno v:
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 10, Iss 3, Pp n/a-n/a (2018)
EMBO Molecular Medicine, 10(3)
Schilperoort, M, van Dam, A D, Hoeke, G, Shabalina, I G, Okolo, A, Hanyaloglu, A C, Dib, L H, Mol, I M, Caengprasath, N, Chan, Y-W, Damak, S, Miller, A R, Coskun, T, Shimpukade, B, Ulven, T, Kooijman, S, Rensen, P C & Christian, M 2018, ' The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat ', EMBO Molecular Medicine, vol. 10, no. 3, e8047 . https://doi.org/10.15252/emmm.201708047
EMBO Molecular Medicine, Vol 10, Iss 3, Pp n/a-n/a (2018)
EMBO Molecular Medicine, 10(3)
Schilperoort, M, van Dam, A D, Hoeke, G, Shabalina, I G, Okolo, A, Hanyaloglu, A C, Dib, L H, Mol, I M, Caengprasath, N, Chan, Y-W, Damak, S, Miller, A R, Coskun, T, Shimpukade, B, Ulven, T, Kooijman, S, Rensen, P C & Christian, M 2018, ' The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat ', EMBO Molecular Medicine, vol. 10, no. 3, e8047 . https://doi.org/10.15252/emmm.201708047
Brown adipose tissue (BAT) activation stimulates energy expenditure in human adults, which makes it an attractive target to combat obesity and related disorders. Recent studies demonstrated a role for G protein‐coupled receptor 120 (GPR120) in BAT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e500a414f38fbfef93af89f8a97f0493
http://wrap.warwick.ac.uk/97936/1/GPR120-agonist-TUG-391-promotes-Christian-2018.pdf
http://wrap.warwick.ac.uk/97936/1/GPR120-agonist-TUG-391-promotes-Christian-2018.pdf
Autor:
Nathalie C Girardin, Maud Frieden, Nicolas Demaurex, Wolfgang F. Graier, Roland Malli, Hélène Jousset
Publikováno v:
Cell Calcium, Vol. 43, No 1 (2008) pp. 83-94
Ca(2+) entry in endothelial cells is a key signaling event as it prolongs the Ca(2+) signal activated by a receptor agonist, and thus allows an adequate production of a variety of compounds. The possible routes that lead to Ca(2+) entry in non-excita
Autor:
Jørn Wulff Helge, Jonas M. Kristensen, Flemming Dela, Steen Larsen, Jørgen F. P. Wojtaszewski
Publikováno v:
Kristensen, J M, Larsen, S, Helge, J W, Dela, F & Wojtaszewski, J F P 2013, ' Two Weeks of Metformin Treatment Enhances Mitochondrial Respiration in Skeletal Muscle of AMPK Kinase Dead but Not Wild Type Mice ', P L o S One, vol. 8, no. 1, e53533 . https://doi.org/10.1371/journal.pone.0053533
PLoS ONE, Vol 8, Iss 1, p e53533 (2013)
PLoS ONE
Kristensen, J M, Larsen, S, Helge, J W, Dela, F & Wojtaszewski, J 2013, ' Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice ', P L o S One, vol. 8, no. 1, e53533 . https://doi.org/10.1371/journal.pone.0053533
PLoS ONE, Vol 8, Iss 1, p e53533 (2013)
PLoS ONE
Kristensen, J M, Larsen, S, Helge, J W, Dela, F & Wojtaszewski, J 2013, ' Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice ', P L o S One, vol. 8, no. 1, e53533 . https://doi.org/10.1371/journal.pone.0053533
Metformin is used as an anti-diabetic drug. Metformin ameliorates insulin resistance by improving insulin sensitivity in liver and skeletal muscle. Reduced mitochondrial content has been reported in type 2 diabetic muscles and it may contribute to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ad8811b52c095759fafdea90dbb1476
https://portal.findresearcher.sdu.dk/da/publications/490befda-7ef7-4d41-89d6-1b18bb5dc383
https://portal.findresearcher.sdu.dk/da/publications/490befda-7ef7-4d41-89d6-1b18bb5dc383
Administered 3 beta-hydroxyandrost-5-ene-7,17-dione (7-oxo-DHEA) is more effective than 3 beta-hydroxyandrost-5-en-7-one (DHEA) as an inducer of liver mitochondrial sn-glycerol-3-phosphate dehydrogenase and cytosolic malic enzyme in rats. Like DHEA,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dedf48a73eaf45be50692bc47a6a267
https://hdl.handle.net/11380/703903
https://hdl.handle.net/11380/703903