Zobrazeno 1 - 10
of 215
pro vyhledávání: '"Cell Nucleus/metabolism"'
Autor:
Knud Larsen, Henrik Callesen
Publikováno v:
Larsen, K E & Callesen, H 2023, ' Developmental expression of CREB1 and NFATC2 in pig embryos ', Molecular Biology Reports, vol. 50, no. 7, pp. 6265-6271 . https://doi.org/10.1007/s11033-023-08501-6
Background: The CREB1 gene encodes the cAMP response element binding protein 1 (CREB1), a leucine zipper transcription factor that regulates cellular gene expression in response to elevated levels of intracellular cAMP. When activated by phosphorylat
Autor:
Sakamoto, Y., Sato, M., Sato, Y., Harada, A., Suzuki, T., Goto, C., Tamura, K., Toyooka, K., Kimura, Hiroshi, Ohkawa, Y., Hara-Nishimura, I., Takagi, S., Matsunaga, S.
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications
The nuclear lamina plays an important role in the regulation of chromatin organization and gene positioning in animals. CROWDED NUCLEI (CRWN) is a strong candidate for the plant nuclear lamina protein in Arabidopsis thaliana but its biological functi
Autor:
Arpan Parichha, Varun Suresh, Mallika Chatterjee, Aditya Kshirsagar, Lihi Ben-Reuven, Tsviya Olender, M. Mark Taketo, Velena Radosevic, Mihaela Bobic-Rasonja, Sara Trnski, Michael J. Holtzman, Nataša Jovanov-Milosevic, Orly Reiner, Shubha Tole
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
The choroid plexus secretes cerebrospinal fluid and is critical for the development and function of the brain. In the telencephalon, the choroid plexus epithelium arises from the Wnt- expressing cortical hem. Canonical Wnt signaling pathway molecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78188af730de0afd2ce5c5adc776ba8f
https://doi.org/10.1038/s41467-021-27602-z
https://doi.org/10.1038/s41467-021-27602-z
Autor:
Katharina F Sonnen, Phong D. Nguyen, Jeroen Bakkers, Veronique E M van der Velden, Hessel Honkoop
Publikováno v:
Development (Cambridge, England)
article-version (VoR) Version of Record
Development (Cambridge), 148(18). Company of Biologists Ltd
article-version (VoR) Version of Record
Development (Cambridge), 148(18). Company of Biologists Ltd
Zebrafish are excellent at regenerating their heart by reinitiating proliferation in pre-existing cardiomyocytes. Studying how zebrafish achieve this holds great potential in developing new strategies to boost mammalian heart regeneration. Neverthele
Publikováno v:
Biomolecules, Vol 11, Iss 54, p 54 (2021)
Biomolecules
Biomolecules
Protein homeostasis, or proteostasis, is crucial for the functioning of a cell, as proteins that are mislocalized, present in excessive amounts, or aberrant due to misfolding or other type of damage can be harmful. Proteostasis includes attaining the
Autor:
Oscar Plunde, Ross O Smith, Qingsen Li, Marco Foiani, Cansaran Saygili Demir, Anders Franco-Cereceda, Marie Hedlund, Sofia Nordling, Lena Claesson-Welsh, Flora Ascione, Miguel Sáinz-Jaspeado, Yindi Ding, Manfred W. Kilimann, Sven-Christian Pawelzik, Pontus Aspenström, Jeffrey Kroon, Giulia Bastianello, Magnus Bäck, Yi Jin, Tatiana V. Petrova, Dinesh Fernando, Geoffrey Daniel
Publikováno v:
Circulation, vol. 144, no. 20, pp. 1629-1645
Circulation, 144(20), 1629-1645. Lippincott Williams and Wilkins
Circulation
Circulation, 144(20), 1629-1645. Lippincott Williams and Wilkins
Circulation
Supplemental Digital Content is available in the text.
Background: PALMD (palmdelphin) belongs to the family of paralemmin proteins implicated in cytoskeletal regulation. Single nucleotide polymorphisms in the PALMD locus that result in reduced
Background: PALMD (palmdelphin) belongs to the family of paralemmin proteins implicated in cytoskeletal regulation. Single nucleotide polymorphisms in the PALMD locus that result in reduced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3442da654a9c825d0299b02dc6da30dc
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-467403
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-467403
Autor:
Elena Godbout, Bernhard Wehrle-Haller, Cristina Has, Leena Bruckner-Tuderman, Andras Kapus, Dong Ok Son, Boris Hinz, Stellar Boo, Stephanie Hume, Sophie Clément, Vincent Sarrazy
Publikováno v:
Cells
Cells, Vol 9, Iss 2702, p 2702 (2020)
Cells, Vol. 9, No 12 (2020) P. 2702
Volume 9
Issue 12
Cells, Vol 9, Iss 2702, p 2702 (2020)
Cells, Vol. 9, No 12 (2020) P. 2702
Volume 9
Issue 12
We identify the focal adhesion protein kindlin-2 as player in a novel mechanotransduction pathway that controls profibrotic cardiac fibroblast to myofibroblast activation. Kindlin-2 is co-upregulated with the myofibroblast marker &alpha
smooth m
smooth m
Autor:
Mar Tulinius, Niklas Darin, Kalliopi Sofou, Linda De Meirleir, Johanna Uusimaa, Charalampos Tzoulis, Pirjo Isohanni, Karin Naess, Elsebet Ostergaard, Irenaeus F.M. de Coo, Tuula Lönnqvist, Laurence A. Bindoff
Publikováno v:
Journal of Medical Genetics, 55(1), 21-27. BMJ Publishing Group
BackgroundLeigh syndrome is a phenotypically and genetically heterogeneous mitochondrial disorder. While some genetic defects are associated with well-described phenotypes, phenotype-genotype correlations in Leigh syndrome are not fully explored.Obje
Autor:
Igor Bazov, Oleg Krishtal, Jan Mulder, Hiroyuki Watanabe, Dineke S. Verbeek, Georgy Bakalkin, Tatiana Yakovleva, Henrik Druid, Kanar Alkass, G. V. Gerashchenko, Craig A. Stockmeier, Olga Kononenko, Åsa Fex Svenningsen, Oleg Dyachok, Malin Andersson, Grazyna Rajkowska
Publikováno v:
Kononenko, O, Bazov, I, Watanabe, H, Gerashchenko, G, Dyachok, O, Verbeek, D S, Alkass, K, Druid, H, Andersson, M, Mulder, J, Fex Svenningsen, Å, Rajkowska, G, Krishtal, O, Yakovleva, T & Bakalkin, G 2017, ' Opioid precursor protein isoform is targeted to the cell nuclei in the human brain ', B B A-General Subjects, vol. 1861, no. 2, pp. 246–255 . https://doi.org/10.1016/j.bbagen.2016.11.002
Biochimica et Biophysica Acta-General Subjects, 1861(2), 246-255. ELSEVIER SCIENCE BV
Biochimica et Biophysica Acta-General Subjects, 1861(2), 246-255. ELSEVIER SCIENCE BV
Background: Neuropeptide precursors are traditionally viewed as proteins giving rise to small neuropeptide molecules. Prodynorphin (PDYN) is the precursor protein to dynorphins, endogenous ligands for the kappa-opioid receptor. Alternative mRNA splic
Autor:
Karoutas, A., Szymanski, W., Rausch, T., Guhathakurta, S., Rog-Zielinska, E. A., Peyronnet, R., Seyfferth, J., Chen, H. R., de Leeuw, R., Herquel, B., Kimura, Hiroshi, Mittler, G., Kohl, P., Medalia, O., Korbel, J. O., Akhtar, A.
Publikováno v:
Nature Cell Biology
While nuclear lamina abnormalities are hallmarks of human diseases, their interplay with epigenetic regulators and precise epigenetic landscape remain poorly understood. Here, we show that loss of the lysine acetyltransferase MOF or its associated NS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3548ff4d5435a5924760feb5f54ba9
https://doi.org/10.5167/uzh-176015
https://doi.org/10.5167/uzh-176015