Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Cell Differentiation/*physiology"'
Autor:
Gillian Fitzgerald, Guillermo Turiel, Tatiane Gorski, Inés Soro-Arnaiz, Jing Zhang, Nicola C. Casartelli, Evi Masschelein, Nicola A. Maffiuletti, Reto Sutter, Michael Leunig, Jean Farup, Katrien De Bock
Publikováno v:
Fitzgerald, G, Turiel, G, Gorski, T, Soro-Arnaiz, I, Zhang, J, Casartelli, N C, Masschelein, E, Maffiuletti, N A, Sutter, R, Leunig, M, Farup, J & De Bock, K 2023, ' MME+ fibro-adipogenic progenitors are the dominant adipogenic population during fatty infiltration in human skeletal muscle ', Communications Biology, vol. 6, pp. 1-21 . https://doi.org/10.1038/s42003-023-04504-y
Communications Biology, 6 (1)
Communications Biology, 6 (1)
Fatty infiltration, the ectopic deposition of adipose tissue within skeletal muscle, is mediated via the adipogenic differentiation of fibro-adipogenic progenitors (FAPs). We used single-nuclei and single-cell RNA sequencing to characterize FAP heter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3044f52d496025c512efcbb91d1ac3c7
Autor:
Pieter S. Hiemstra, Evelien Eenjes, Irwin K M Reiss, Annelies M. Slats, Robbert J. Rottier, Sander van Riet, Hans Clevers, Dennis K. Ninaber, André A. Kroon, P. Padmini S.J. Khedoe, Marjon J Buscop-van Kempen, Anne Boerema-de Munck
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology, 321(4), L775-L786. American Physiological Society
American Journal of Physiology-Lung Cellular and Molecular Physiology, 321(4), L775-L786. American Physiological Society
American Journal of Physiology-Lung Cellular and Molecular Physiology, 321(4), L775-L786. AMER PHYSIOLOGICAL SOC
American Journal of Physiology-Lung Cellular and Molecular Physiology, 321(4), L775-L786. American Physiological Society
American Journal of Physiology-Lung Cellular and Molecular Physiology, 321(4), L775-L786. AMER PHYSIOLOGICAL SOC
Air-liquid interface (ALI) cultures are frequently used in lung research but require substantial cell numbers that cannot readily be obtained from patients. We explored whether organoid expansion [three-dimensional (3D)] can be used to establish ALI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a14168f61ae2b61d818774ddd643a0aa
https://pure.knaw.nl/portal/en/publications/aaa00eea-135c-4217-a77c-7fb4306b005a
https://pure.knaw.nl/portal/en/publications/aaa00eea-135c-4217-a77c-7fb4306b005a
Autor:
Gdula, M. R., Poterlowicz, K., Mardaryev, A. N., Sharov, A. A., Peng, Y., Fessing, M. Y., Botchkarev, V. A.
The nucleus of epidermal keratinocytes (KCs) is a complex and highly compartmentalized organelle, whose structure is markedly changed during terminal differentiation and transition of the genome from a transcriptionally active state seen in the basal
Externí odkaz:
http://hdl.handle.net/10454/5985
Autor:
Lisa Henkel, Karen Grütz, Anne Grünewald, Anna Kutschenko, Johanne Heine, Selma Staege, Andreas Hermann, Philip Seibler, Hannes Glaß, Norman Kalmbach, Florian Wegner, Thomas Gschwendtberger
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 7
International Journal of Molecular Sciences, Vol 22, Iss 3565, p 3565 (2021)
International journal of molecular sciences 22(7), 3565 (2021). doi:10.3390/ijms22073565
Volume 22
Issue 7
International Journal of Molecular Sciences, Vol 22, Iss 3565, p 3565 (2021)
International journal of molecular sciences 22(7), 3565 (2021). doi:10.3390/ijms22073565
Myoclonus-dystonia (DYT-SGCE, formerly DYT11) is characterized by alcohol-sensitive, myoclonic-like appearance of fast dystonic movements. It is caused by mutations in the SGCE gene encoding ε-sarcoglycan leading to a dysfunction of this transmembra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5efd60b20c5aaaf2112bf11ccfefbe65
Publikováno v:
Development
Development (Cambridge, England)
article-version (VoR) Version of Record
Development (Cambridge, England)
article-version (VoR) Version of Record
Despite striking parallels between the fields of developmental biology and adult tissue homeostasis, these are disconnected in contemporary research. Although development describes tissue generation and homeostasis describes tissue maintenance, it is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8d887a604d8567c7f8492a4f1407ce
Autor:
Barbara Korzeniowska, Krzysztof Wrzesinski, Chrisna Gouws, Stephen J. Fey, Carlemi Calitz, Helle Sedighi Frandsen
Publikováno v:
Methods in Molecular Biology ISBN: 9781071612453
Wrzesinski, K, Frandsen, H S, Calitz, C, Gouws, C, Korzeniowska, B & Fey, S J 2021, Clinostat 3D Cell Culture : Protocols for the Preparation and Functional Analysis of Highly Reproducible, Large, Uniform Spheroids and Organoids . in T A L Brevini, A Fazeli & K Turksen (eds), Next Generation Culture Platforms for Reliable In Vitro Models : Methods and Protocols . Humana Press, Methods in Molecular Biology, vol. 2273, pp. 17-62 . https://doi.org/10.1007/978-1-0716-1246-0_2
Wrzesinski, K, Frandsen, H S, Calitz, C, Gouws, C, Korzeniowska, B & Fey, S J 2021, Clinostat 3D Cell Culture : Protocols for the Preparation and Functional Analysis of Highly Reproducible, Large, Uniform Spheroids and Organoids . in T A L Brevini, A Fazeli & K Turksen (eds), Next Generation Culture Platforms for Reliable In Vitro Models : Methods and Protocols . Humana Press, Methods in Molecular Biology, vol. 2273, pp. 17-62 . https://doi.org/10.1007/978-1-0716-1246-0_2
Growing cells as 3D structures need not be difficult. Often, it is not necessary to change cell type, additives or growth media used. All that needs to be changed is the geometry: cells (whether primary, induced pluripotent, transformed or immortal)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0ab0bdffa4401be20952ab1b3b16ef
https://doi.org/10.1007/978-1-0716-1246-0_2
https://doi.org/10.1007/978-1-0716-1246-0_2
Autor:
Moa Stenudd, Hanna Sabelström, Enric Llorens-Bobadilla, Margherita Zamboni, Hans Blom, Hjalmar Brismar, Shupei Zhang, Onur Basak, Hans Clevers, Christian Göritz, Fanie Barnabé-Heider, Jonas Frisén
Publikováno v:
Cell Reports, 38(9). Cell Press
Spinal cord ependymal cells display neural stem cell properties in vitro and generate scar-forming astrocytes and remyelinating oligodendrocytes after injury. We report that ependymal cells are functionally heterogeneous and identify a small subpopul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4554288f8eca4c4692f0528146e31d8c
https://pubmed.ncbi.nlm.nih.gov/35235796
https://pubmed.ncbi.nlm.nih.gov/35235796
Autor:
Claire V. Harper, Louise Ashall, Giorgos Minas, Michael R. H. White, Dan J. Woodcock, David A. Rand
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 8, p e1008076 (2020)
PLoS Computational Biology
PLoS Computational Biology
We consider how a signalling system can act as an information hub by multiplexing information arising from multiple signals. We formally define multiplexing, mathematically characterise which systems can multiplex and how well they can do it. While t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78fe48285c1eafb8d1eaedc1df1d252d
http://wrap.warwick.ac.uk/139682/7/WRAP-Multiplexing-information-flow-through-dynamic-signalling-systems-Rand-2020.pdf
http://wrap.warwick.ac.uk/139682/7/WRAP-Multiplexing-information-flow-through-dynamic-signalling-systems-Rand-2020.pdf
Publikováno v:
Abdallah, B, Alzahrani, A M & Kassem, M 2018, ' Secreted Clusterin protein inhibits osteoblast differentiation of bone marrow mesenchymal stem cells by suppressing ERK1/2 signaling pathway ', Bone, vol. 110, pp. 221-229 . https://doi.org/10.1016/j.bone.2018.02.018
Secreted Clusterin (sCLU, also known as Apolipoprotein J) is an anti-apoptotic glycoprotein involved in the regulation of cell proliferation, lipid transport, extracellular tissue remodeling and apoptosis. sCLU is expressed and secreted by mouse bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b87a65599f7d54cacaef9ad69e0e2ae0
https://doi.org/10.1016/j.bone.2018.02.018
https://doi.org/10.1016/j.bone.2018.02.018