Expression Pattern of Purinergic Signaling Components in Colorectal Cancer Cells and Differential Cellular Outcomes Induced by Extracellular ATP and Adenosine

Autor: Clémentine Dillard, Chloé Borde, Ammara Mohammad, Virginie Puchois, Laurent Jourdren, Annette K. Larsen, Michèle Sabbah, Vincent Maréchal, Alexandre E. Escargueil, Elodie Pramil

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 21, p 11472 (2021)

The purine nucleotide adenosine triphosphate (ATP) is known for its fundamental role in cellular bioenergetics. However, in the last decades, different works have described emerging functions for ATP, such as that of a danger signaling molecule actin

Externí odkaz: https://doaj.org/article/574cd34048974f7bb0e0f83a21f776ec

Expression Pattern of Purinergic Signaling Components in Colorectal Cancer Cells and Differential Cellular Outcomes Induced by Extracellular ATP and Adenosine

Autor: Annette K. Larsen, Ammara Mohammad, Vincent Maréchal, Alexandre E. Escargueil, Laurent Jourdren, Chloé Borde, Virginie Puchois, Michèle Sabbah, Clémentine Dillard, Elodie Pramil

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 11472, p 11472 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences, MDPI, 2021, 22 (21), pp.11472. ⟨10.3390/ijms222111472⟩

International audience; The purine nucleotide adenosine triphosphate (ATP) is known for its fundamental role in cellular bioenergetics. However, in the last decades, different works have described emerging functions for ATP, such as that of a danger

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a97bae4cf2d62a140d0ec10074ea5a
https://pubmed.ncbi.nlm.nih.gov/34768902

Molecular Response to Combined Molecular- and External Radiotherapy in Head and Neck Squamous Cell Carcinoma (HNSCC)

Autor: Mechthild Krause, Ariane Christel Kühn, Louis Feindt, Annett Linge, Michael Baumann, Cläre von Neubeck, Lydia Koi, Hans-Jürgen Pietzsch, Antje Dietrich, Wiebke Sihver, Jörg Kotzerke, Robert Freudenberg, Johannes Müller, Enes Cevik, Treewut Rassamegevanon, Steffen Löck

Publikováno v: Cancers
Cancers, Vol 13, Iss 5595, p 5595 (2021)
Cancers 13(2021)22, 5595
Volume 13
Issue 22

Combination treatment of molecular targeted and external radiotherapy is a promising strategy and was shown to improve local tumor control in a HNSCC xenograft model. To enhance the therapeutic value of this approach, this study investigated the unde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8215105d478824522bb06ccc3275f53c
https://doi.org/10.3390/cancers13225595

Co-Targeting Intrinsic and Extrinsic Apoptosis to Maximize Cell Death Induction in Venetoclax-Resistant AML Cells

Autor: Bing Z. Carter, Wenjing Tao, Yuki Nishida, Michael Andreeff, Lauren B Ostermann, Ran Tao, Po Yee Mak, Steffen Boettcher, Yifan Zhai, Hong Mu-Mosley, Eric Lang, Dajun Yang

Publikováno v: Blood. 138:3332-3332

Bcl-2 family protein-regulated intrinsic and IAP-family protein-regulated extrinsic pathways are two major apoptotic cell death mechanisms. Components of both pathways are regulated by the tumor suppressor p53. Although combinations of Bcl-2 inhibito

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6398cb9160e1d0cf817b5b006cc97652
https://doi.org/10.1182/blood-2021-148127

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