Conjugative DNA transfer induces the bacterial SOS response and promotes antibiotic resistance development through integron activation

Autor: Zeynep Baharoglu, Didier Mazel, David Bikard

Publikováno v: PLoS Genetics
PLoS Genetics, 2010, 6 (10), pp.e1001165. ⟨10.1371/journal.pgen.1001165⟩
PLoS Genetics, Public Library of Science, 2010, 6 (10), pp.e1001165. ⟨10.1371/journal.pgen.1001165⟩
PLoS Genetics, Vol 6, Iss 10, p e1001165 (2010)
Scopus-Elsevier

Conjugation is one mechanism for intra- and inter-species horizontal gene transfer among bacteria. Conjugative elements have been instrumental in many bacterial species to face the threat of antibiotics, by allowing them to evolve and adapt to these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b45ed7ad4a49a34298b406efa778569
https://hal-pasteur.archives-ouvertes.fr/pasteur-02477623

Compartmentation of redox metabolism in malaria parasites

Autor: Katja Becker, Jude M. Przyborski, Sebastian Kehr, Stefan Rahlfs, Nicole Sturm

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 6, Iss 12, p e1001242 (2010)

Malaria, caused by the apicomplexan parasite Plasmodium, still represents a major threat to human health and welfare and leads to about one million human deaths annually. Plasmodium is a rapidly multiplying unicellular organism undergoing a complex d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c37ab1c97a6dfbe41634592e2d24c2a
https://pubmed.ncbi.nlm.nih.gov/21203490

A new fluorescence-based method identifies protein phosphatases regulating lipid droplet metabolism

Autor: Juliana B. Madeira, Bruno L. Bozaquel-Morais, Clarissa M. Maya-Monteiro, Claudio A. Masuda, Mónica Montero-Lomelí

Publikováno v: PLoS ONE
PLoS ONE, Vol 5, Iss 10, p e13692 (2010)

In virtually every cell, neutral lipids are stored in cytoplasmic structures called lipid droplets (LDs) and also referred to as lipid bodies or lipid particles. We developed a rapid high-throughput assay based on the recovery of quenched BODIPY-fluo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a19b3317682b29b0de39cfd471f13319
https://pubmed.ncbi.nlm.nih.gov/21060891

Metabolomics to unveil and understand phenotypic diversity between pathogen populations

Autor: David G. Watson, Kirstyn Brunker, Andris Jankevics, Jean-Claude Dujardin, Richard A. Scheltema, Saskia Decuypere, Graham H. Coombs, Rainer Breitling, Suman Rijal, Ruben T'Kindt

Publikováno v: PLoS Neglected Tropical Diseases, Vol 4, Iss 11, p e904 (2010)
PLoS neglected tropical diseases
PLoS Neglected Tropical Diseases; Vol 4
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, 4(11):904. PUBLIC LIBRARY SCIENCE

Leishmaniasis is a debilitating disease caused by the parasite Leishmania. There is extensive clinical polymorphism, including variable responsiveness to treatment. We study Leishmania donovani parasites isolated from visceral leishmaniasis patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de007a7a53510bbc7b8599dc450adb45
http://europepmc.org/articles/PMC2994915?pdf=render

Serious overestimation in quantitative PCR by circular (supercoiled) plasmid standard: microalgal pcna as the model gene

Autor: Yubo Hou, Lilibeth Miranda, Huan Zhang, Senjie Lin

Publikováno v: PLoS ONE, Vol 5, Iss 3, p e9545 (2010)
PLoS ONE

Quantitative real-time PCR (qPCR) has become a gold standard for the quantification of nucleic acids and microorganism abundances, in which plasmid DNA carrying the target genes are most commonly used as the standard. A recent study showed that super

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c576c70e1060fcd102df2ae15743ac15
http://europepmc.org/articles/PMC2832698?pdf=render