Zobrazeno 1 - 10
of 813
pro vyhledávání: '"Cell Biology/Gene Expression"'
Publikováno v:
PLoS Biology
Chromatin organizer SATB1 and Wnt transducer β-catenin form a complex and regulate expression of GATA3 and TH2 cytokines in Wnt-dependent manner and orchestrate TH2 lineage commitment.
In vertebrates, the conserved Wnt signalling cascade promot
In vertebrates, the conserved Wnt signalling cascade promot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b3b62f0f2ce8508e6158ff34ff23a558
https://pubmed.ncbi.nlm.nih.gov/20126258
https://pubmed.ncbi.nlm.nih.gov/20126258
Autor:
Joana Sequeira-Mendes, Neil Brockdorff, Derek Huntley, Anwyn Apedaile, Ramon Diaz-Uriarte, María Gómez
Publikováno v:
PLoS Genetics, Vol 5, Iss 4, p e1000446 (2009)
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
PLoS Genetics
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
PLoS Genetics
Genomic mapping of DNA replication origins (ORIs) in mammals provides a powerful means for understanding the regulatory complexity of our genome. Here we combine a genome-wide approach to identify preferential sites of DNA replication initiation at 0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df81c6e3c29e56f4fe510355b93cefbd
https://ora.ox.ac.uk/objects/uuid:eeed55a8-5a1a-4bf1-ac8d-2ec3cc6fc8af
https://ora.ox.ac.uk/objects/uuid:eeed55a8-5a1a-4bf1-ac8d-2ec3cc6fc8af
Autor:
Robert G.J. Vries, Albert J. R. Heck, Pantelis Hatzis, Tokameh Mahmoudi, Nadia Taouatas, Vivian S. W. Li, Hans Clevers, Hans Teunissen, Sylvia F. Boj, Harry Begthel, Jeroen Korving, Shabaz Mohammed
Publikováno v:
PLoS Biology, 8(11). Public Library of Science
PLoS Biology
PLoS Biology, Vol 8, Iss 11, p e1000539 (2010)
PLoS Biology
PLoS Biology, Vol 8, Iss 11, p e1000539 (2010)
The leukemia-associated Mllt10/Af10 and its partner the histone methyltransferase Dot1l are identified as Tcf4/β-catenin co-activators and shown to be essential for Wnt-driven endogenous gene expression, intestinal development and homeostasis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf3e12c4305daee57f3a10d4a6859fdc
https://doi.org/10.1371/journal.pbio.1000539
https://doi.org/10.1371/journal.pbio.1000539
Autor:
Andrew Jefferson, Giorgio Gimelli, Daniela Moralli, Mohammed Yusuf, Stefano Colella, Jiannis Ragoussis, Natalie Wilson, Emanuela V. Volpi
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11364 (2010)
Plos One 6 (5), 19 p.. (2010)
PLoS ONE
PLoS ONE, Public Library of Science, 2010, 5 (6), 19 p. ⟨10.1371/journal.pone.0011364⟩
Plos One 6 (5), 19 p.. (2010)
PLoS ONE
PLoS ONE, Public Library of Science, 2010, 5 (6), 19 p. ⟨10.1371/journal.pone.0011364⟩
International audience; The ICF syndrome is a rare autosomal recessive disorder, the most common symptoms of which are immunodeficiency, facial anomalies and cytogenetic defects involving decondensation and instability of chromosome 1, 9 and 16 centr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171dbbb4ef573600ba53ca2bbdd1b282
https://ora.ox.ac.uk/objects/uuid:baa90fbb-b856-49b6-b179-128ce6c2e144
https://ora.ox.ac.uk/objects/uuid:baa90fbb-b856-49b6-b179-128ce6c2e144
Autor:
Eugeny A. Elisaphenko, Pavel A. Dyban, E.V. Grigor'eva, Ekaterina M. Noniashvili, Sergey Ya. Slobodyanyuk, A. I. Zhelezova, Andrey P. Dyban, Neil Brockdorff, Alexander I. Shevchenko, N. A. Mazurok, Tatyana B. Nesterova, A. G. Shilov, Suren M. Zakian
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 9, p e7161 (2009)
PLoS ONE, Vol 4, Iss 9, p e7161 (2009)
The derivation of stable multipotent trophoblast stem (TS) cell lines from preimplantation, and early postimplantation mouse embryos has been reported previously. FGF4, and its receptor FGFR2, have been identified as embryonic signaling factors respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec9f3463f3f815093d58a8b0512a52e4
https://doi.org/10.1371/journal.pone.0007161
https://doi.org/10.1371/journal.pone.0007161
Autor:
Gioacchino Natoli, Francesca De Santa, Flore Mietton, Chia-Lin Wei, Iros Barozzi, Betsabeh Khoramian Tusi, Sara Polletti, Heiko Muller, Serena Ghisletti, Jiannis Ragoussis
Publikováno v:
PLoS Biology, Vol 8, Iss 5, p e1000384 (2010)
PLoS Biology
PLoS Biology; Vol 8
PLoS Biology
PLoS Biology; Vol 8
A substantial fraction of extragenic Pol II transcription sites coincides with transcriptional enhancers, which may be relevant for functional annotation of mammalian genomes.
Mammalian genomes are pervasively transcribed outside mapped protein-
Mammalian genomes are pervasively transcribed outside mapped protein-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb5800846abc293902ba1199983024c
https://ora.ox.ac.uk/objects/uuid:35162c05-2208-4028-bf35-d685e2729d16
https://ora.ox.ac.uk/objects/uuid:35162c05-2208-4028-bf35-d685e2729d16
Autor:
Tünde Szatmári, George N. Tzanakakis, Anders Hjerpe, David Brodin, Katalin Dobra, Ilona Kovalszky, Filip Mundt, László Szilák, Fang Zong, Eleni Fthenou
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 6, p e14816 (2011)
PLoS ONE, Vol 6, Iss 6, p e14816 (2011)
BackgroundSyndecans are proteoglycans whose core proteins have a short cytoplasmic domain, a transmembrane domain and a large N-terminal extracellular domain possessing glycosaminoglycan chains. Syndecans are involved in many important cellular proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467efdecba5d38298c8affd12aeb7f5f
http://europepmc.org/articles/PMC3121713
http://europepmc.org/articles/PMC3121713
Autor:
Mary, Muers
Publikováno v:
PLoS Biology
Cycling of gene expression in individual cells is controlled by dynamic chromatin remodeling.
In individual mammalian cells the expression of some genes such as prolactin is highly variable over time and has been suggested to occur in stochastic
In individual mammalian cells the expression of some genes such as prolactin is highly variable over time and has been suggested to occur in stochastic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba87eeef99221c83a64238356f2326d1
https://pubmed.ncbi.nlm.nih.gov/21532732
https://pubmed.ncbi.nlm.nih.gov/21532732
Autor:
Adrian J. Harwood, Mridu Kapur, Melanie Keim, Karina McQuillan, Robin S.B. Williams, Jonathan Ryves, Karin E. Weening, Emma Dalton, Regina Teo, Ben Rogers, Jason S. King
Publikováno v:
PLoS One, 5 (6)
PLoS ONE
PLoS ONE, Vol 5, Iss 6, p e11151 (2010)
PLoS ONE
PLoS ONE, Vol 5, Iss 6, p e11151 (2010)
Lithium (Li(+)) is a common treatment for bipolar mood disorder, a major psychiatric illness with a lifetime prevalence of more than 1%. Risk of bipolar disorder is heavily influenced by genetic predisposition, but is a complex genetic trait and, to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e058e1a9c3a977285127ac45d2250f2
https://repository.royalholloway.ac.uk/items/f3d441f9-de40-d036-f9cd-5d573b26e4ea/6/
https://repository.royalholloway.ac.uk/items/f3d441f9-de40-d036-f9cd-5d573b26e4ea/6/
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 7, Iss 3, p e1001334 (2011)
PLoS Genetics, Vol 7, Iss 3, p e1001334 (2011)
The chromosomes of eukaryotes are organized into structurally and functionally discrete domains. This implies the presence of insulator elements that separate adjacent domains, allowing them to maintain different chromatin structures. We show that th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dccec660f89310280847ded133305b9
http://europepmc.org/articles/PMC3060074
http://europepmc.org/articles/PMC3060074