Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Cell Adhesion/drug effects"'
Autor:
Karim Bouzakri, Katharina Rickenbach, Caroline Arous, Michel Pinget, Bernhard Wehrle-Haller, Maria L. Mizgier
Publikováno v:
Journal of Biological Chemistry, Vol. 295, No 49 (2020) pp. 16510-16528
The Journal of Biological Chemistry
The Journal of Biological Chemistry
Elevated levels of fasting insulin release and insufficient glucose-stimulated insulin secretion (GSIS) are hallmarks of diabetes. Studies have established cross-talk between integrin signaling and insulin activity, but more details of how integrin-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4063a6b9e04781fc7fe5d6ec0c61ec14
https://doi.org/10.1074/jbc.ra120.012957
https://doi.org/10.1074/jbc.ra120.012957
Autor:
Zaineb Abdelkafi-Koubaa, Mohamed El Ayeb, Erij Messadi, Najet Srairi Abid, Maram Morjen, Jed Jebali, Houcemeddine Othman, José Luis, Naziha Marrakchi
Publikováno v:
International Journal of Biological Macromolecules
International Journal of Biological Macromolecules, 2018, 117, pp.790-799. ⟨10.1016/j.ijbiomac.2018.05.230⟩
International Journal of Biological Macromolecules, Elsevier, 2018, 117, pp.790-799. ⟨10.1016/j.ijbiomac.2018.05.230⟩
International Journal of Biological Macromolecules, 2018, 117, pp.790-799. ⟨10.1016/j.ijbiomac.2018.05.230⟩
International Journal of Biological Macromolecules, Elsevier, 2018, 117, pp.790-799. ⟨10.1016/j.ijbiomac.2018.05.230⟩
International audience; Through the recent development of knowledge in biotechnology and bioinformatics, snake venoms are widely used to develop new drugs to treat diseases such as hypertension and cancer. We have previously reported that Lebetin 2 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90e51ea875cbc6ee35aa79287c5c9f3b
https://doi.org/10.1016/j.ijbiomac.2018.05.230
https://doi.org/10.1016/j.ijbiomac.2018.05.230
Autor:
Anja Seckinger, Giorgio Mori, Volker Martin, Anna Luise Grab, Elisabetta Ada Cavalcanti-Adam, Slobodan Vukicevic, Francesca Posa, Dirk Hose
Publikováno v:
Cells
Volume 8
Issue 12
Volume 8
Issue 12
We report on the covalent immobilization of bone morphogenetic protein 6 (BMP-6) and its co-presentation with integrin ligands on a nanopatterned platform to study cell adhesion and signaling responses which regulate the transdifferentiation of myobl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::585faf31fe1d433826775658439c7746
Autor:
Marius Ringelstein, L. M. Yshii, Ilka Kleffner, Stephen W. Reddel, Brigitte Wildemann, Todd A. Hardy, Markus Schwaninger, Guillaume Martin-Blondel, Nicholas Schwab, Delphine Loussouarn, John Parratt, Marc Pawlitzki, Henrike Plate, Eduardo Beltrán, Catharina C. Gross, Anna R. Tröscher, Tanja Kuhlmann, Tilman Schneider-Hohendorf, Klaus Dornmair, Jan Dörr, Roland S. Liblau, Urvashi Bhatia, Hans Lassmann, Sven G. Meuth, Luisa Klotz, Sebastian Herich, Markus Kraemer, Jan Bauer, Céline Meyer, David-Axel Laplaud, Wolfgang Brück, Romana Höftberger, Michael Barnett, Michael E. Buckland, Andreas Schulte-Mecklenbeck, Heinz Wiendl
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.5779. ⟨10.1038/s41467-019-13593-5⟩
Nature Communications, 2019, 10, pp.5779. ⟨10.1038/s41467-019-13593-5⟩
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.5779. ⟨10.1038/s41467-019-13593-5⟩
Nature Communications, 2019, 10, pp.5779. ⟨10.1038/s41467-019-13593-5⟩
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
International audience; Neuroinflammation is often associated with blood-brain-barrier dysfunction, which contributes to neurological tissue damage. Here, we reveal the pathophysiology of Susac syndrome (SuS), an enigmatic neuroinflammatory disease w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca645613d7be9f13495f97945a31e9dd
https://www.hal.inserm.fr/inserm-02448919/file/s41467-019-13593-5.pdf
https://www.hal.inserm.fr/inserm-02448919/file/s41467-019-13593-5.pdf
Autor:
Lamia Borchani, Ivana Catacchio, Antonio Giovanni Solimando, Hafed Majdoub, Imen Jridi, Maria Antonia Frassanito, Delavar Shahbazzadeh, Angelo Vacca, Mohamed El Ayeb, Domenico Ribatti
Publikováno v:
Toxicon
Toxicon, Elsevier, 2017, 126, pp.38-46. ⟨10.1016/j.toxicon.2016.12.001⟩
Toxicon, Elsevier, 2017, 126, pp.38-46. ⟨10.1016/j.toxicon.2016.12.001⟩
International audience; In a previous study, we reported the identification of Hemilipin, the first secreted heterodimeric phospholipase A2 (sPLA2) from Hemiscorpius lepturus scorpion venom and demonstrated its effective inhibition of all angiogenesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95314e4d3c0dadcf15c9e75a135888ce
https://doi.org/10.1016/j.toxicon.2016.12.001
https://doi.org/10.1016/j.toxicon.2016.12.001
Autor:
Imen Touihri-Barakati, Belgacem Hanchi, José Luis, Abdennacer Boulila, Olfa Kallech-Ziri, Karim Hosni, Naziha Marrakchi, Khaoula Khwaldia
Publikováno v:
Biomedicine and Pharmacotherapy
Biomedicine and Pharmacotherapy, Elsevier Masson, 2016, 84, pp.1223-1232. ⟨10.1016/j.biopha.2016.10.035⟩
Biomedicine and Pharmacotherapy, Elsevier Masson, 2016, 84, pp.1223-1232. ⟨10.1016/j.biopha.2016.10.035⟩
International audience; In the present study, the effect of Ecbalium elaterium seed oil on adhesion, migration and proliferation of human brain cancer cell line (U87) was determined. Treatment of U87 cell line with the seed oil resulted in strong inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::defb1ac9fb0715fda2d704342ce2bc18
https://doi.org/10.1016/j.biopha.2016.10.035
https://doi.org/10.1016/j.biopha.2016.10.035
Autor:
Hazem Ben Mabrouk, Oussema Khamessi, Michel De Waard, Mejdoub Hafedh, Houcemeddine Othman, R. Kharrat, Najet Srairi-Abid, Naziha Marrakchi, Rym ElFessi-Magouri
Publikováno v:
International Journal of Biological Macromolecules
International Journal of Biological Macromolecules, Elsevier, 2018, 120 (B), pp.1777-1788. ⟨10.1016/j.ijbiomac.2018.09.180⟩
International Journal of Biological Macromolecules, Elsevier, 2018, 120 (B), pp.1777-1788. ⟨10.1016/j.ijbiomac.2018.09.180⟩
International audience; the first scorpion peptide with dual disintegrin activity on α1β1 and αvβ3 integrins. Abstract: Scorpion peptides are well known for their pharmaceutical potential on different targets. These include mainly the ion channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::764ccd918c1c54e341c1adf20a3259c4
https://hal-riip.archives-ouvertes.fr/pasteur-02003807
https://hal-riip.archives-ouvertes.fr/pasteur-02003807
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics, Vol. 140 (2019) pp. 100-108
Wound healing, when compromised, may be guided by biological cues such as Arg-Gly-Asp (RGD), a peptide known to induce cell adhesion and migration, eventually combined with adapted nanocarriers. Three different formulations were prepared and investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039e0cb76a363f238219579e9d6aac79
https://pubmed.ncbi.nlm.nih.gov/31085312
https://pubmed.ncbi.nlm.nih.gov/31085312
Autor:
José S. Ramalho, Mylène A. Carrascal, Isabel Serrano, Maria José Oliveira, Robert Sackstein, Constança Amaral, M. R. Martins, Cláudia Pen, Mariana Silva, Carlota Pascoal, Paula A. Videira
Publikováno v:
Molecular Oncology, Vol 12, Iss 5, Pp 579-593 (2018)
Molecular Oncology
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Molecular Oncology
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Breast cancer tissue overexpresses fucosylated glycans, such as sialyl-Lewis X/A (sLeX/A), and a-1,3/4-fucosyltransferases (FUTs) in relation to increased disease progression and metastasis. These glycans in tumor circulating cells mediate binding to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40f2f6c5f521e554575a4c90c66c6db6
https://hdl.handle.net/10216/127061
https://hdl.handle.net/10216/127061
Autor:
Bastiaan D. Ippel, Noortje A.M. Bax, Carlijn V. C. Bouten, Patricia Y. W. Dankers, Sergio Spaans, Henk M. Keizer, D. F. A. de Bont, Peter Paul K.H. Fransen
Publikováno v:
Biomaterials Science, 5(8), 1541-1548. Royal Society of Chemistry
Optimization of cell-material interactions is crucial for the success of synthetic biomaterials in guiding tissue regeneration. To do so, catechol chemistry is often used to introduce adhesiveness into biomaterials. Here, a supramolecular approach ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8111f8872e816da1bead32e44b5688b
https://pubmed.ncbi.nlm.nih.gov/28636048
https://pubmed.ncbi.nlm.nih.gov/28636048