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Autor:
Mamuka Kvaratskhelia, Celine Tse, Ronald M. Levy, Emilio Gallicchio, Nanjie Deng, Lauren Wickstrom
Publikováno v:
Biophys J
We report the free-energy landscape and thermodynamics of the protein-protein association responsible for the drug-induced multimerization of HIV-1 integrase (IN). Allosteric HIV-1 integrase inhibitors promote aberrant IN multimerization by bridging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::992465a1f6758b4d6bf913813c5549b6
https://doi.org/10.1016/j.bpj.2020.08.005
https://doi.org/10.1016/j.bpj.2020.08.005
