Výsledky vyhledávání - "Celine Tohme"

Akademický článek

ZLN005, a PGC-1α Activator, Protects the Liver against Ischemia–Reperfusion Injury and the Progression of Hepatic Metastases

Autor: Celine Tohme, Tony Haykal, Ruiqi Yang, Taylor J. Austin, Patricia Loughran, David A. Geller, Richard L. Simmons, Samer Tohme, Hamza O. Yazdani

Publikováno v: Cells, Vol 13, Iss 17, p 1448 (2024)

Background: Exercise can promote sustainable protection against cold and warm liver ischemia–reperfusion injury (IRI) and tumor metastases. We have shown that this protection is by the induction of hepatic mitochondrial biogenesis pathway. In this

Externí odkaz: https://doaj.org/article/fb2e62d8e57f457099f6cc270bf554e4

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Abstract 1317: Exercise training prevents exosome mediated pre-metastatic niche formation in the liver

Autor: Ruiqi Yang, Tony Haykal, Celine Tohme, Ronghua Wang, Christof Kaltenmeier, David Geller, Hamza Yazdani, Samer Tohme

Publikováno v: Cancer Research. 83:1317-1317

Introduction: Primary tumor cells release exosomes facilitating pre-metastatic niche formation in distant organs, initiating the process of metastasis. As metastasis is the main prognostic factor for patients, it is essential to understand the pre-me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9edc9227a7aeb79a27db1cd7d600b11a
https://doi.org/10.1158/1538-7445.am2023-1317

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Abstract 5136: Surgical stress promotes long-lasting protumorigenic changes in bone marrow derived progenitor cells

Autor: Hamza O. Yazdani, Tony Haykal, Ruiqi Yang, Celine Tohme, David A. Geller, Samer Tohme

Publikováno v: Cancer Research. 83:5136-5136

Introduction: Surgery is a crucial intervention for cancer patients. However, the perioperative period is characterized by an increased risk for accelerated growth of metastatic disease. Our recent work shows that the protumorigenic systemic inflamma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ec639c9d73e4c977f136cd2beb66f69c
https://doi.org/10.1158/1538-7445.am2023-5136

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Abstract 5129: Neutrophil extracellular traps induced by surgical stress regulate cancer metabolism leading to tumor growth

Autor: Tony Haykal, Ruiqi Yang, Celine Tohme, Ronghua Wang, David Geller, Christof Kaltenmeier, Hamza Yazdani, Samer Tohme

Publikováno v: Cancer Research. 83:5129-5129

Introduction: Surgery is a crucial intervention to cure malignancies. However, evidence shows that the surgical insult and its accompanying immune response can enhance tumor growth and metastasis. Neutrophil Extracellular Traps (NETs) released system

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c572967cfe2087f2fac432680e1a6a35
https://doi.org/10.1158/1538-7445.am2023-5129

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