Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Celine N. Martineau"'
Publikováno v:
microPublication biology. 2022
Drechmeria coniospora is a natural fungal pathogen of Caenorhabditis elegans. Fungal spores are able to pierce the cuticle of the worm, leading to hyphal growth in the entire organism. C. elegans counters the infection by triggering a rapid innate im
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 7, p e1008002 (2020)
PLoS computational biology, 16 (7
PLoS Computational Biology
PLoS computational biology, 16 (7
PLoS Computational Biology
Ageing affects a wide range of phenotypes at all scales, but an objective measure of ageing remains challenging, even in simple model organisms. To measure the ageing process, we characterized the sequence of alterations of multiple phenotypes at org
Ageing affects a wide range of phenotypes at all scales, but an objective measure of ageing remains challenging, even in simple model organisms. To measure the ageing process, we characterized the sequence of alterations of multiple phenotypes at org
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0c68ea7dacc0adc466d5084c70e0d1
http://hdl.handle.net/10044/1/81444
http://hdl.handle.net/10044/1/81444
Autor:
Francesco A. Aprile, Michele Vendruscolo, Wytse Hogewerf, Anne Steinhof, Renée I. Seinstra, Esther Stroo, Tristan V. de Jong, Mohamad Amr Zaini, Victor Guryev, Olga Sin, Roméo Willinge Prins, Erich E. Wanker, Valerie Reinke, Ellen A. A. Nollen, Hai Hui Wang, Michelle M. Kudron, Alejandro Mata-Cabana, Celine N. Martineau, Cornelis F. Calkhoven
Publikováno v:
Molecular Cell
Molecular Cell, 65(6), 1096-1108. CELL PRESS
Molecular Cell, 65(6), 1096-1108. CELL PRESS
Summary Protein aggregation is associated with age-related neurodegenerative disorders, such as Alzheimer’s and polyglutamine diseases. As a causal relationship between protein aggregation and neurodegeneration remains elusive, understanding the ce
Autor:
Renée I. Seinstra, Baskaner B, Patrick Laurent, Nollen Eaa, William R Schafer, Brown Aex, Celine N. Martineau
Neurodegenerative diseases may be the cause or the consequence of an acceleration of physiological ageing. Evidence for this concept is lacking due to practical limitations of human studies. Here, we compared the processes of physiological and pathol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2369c71c9172b2c358d42aba5a0118c
https://doi.org/10.1101/555847
https://doi.org/10.1101/555847
Autor:
Bora Baskaner, Patrick Laurent, Celine N. Martineau, Renée I. Seinstra, William R Schafer, André Ex Brown, Ellen A. A. Nollen
Publikováno v:
SSRN Electronic Journal.
Neurodegenerative diseases are suggested as a cause or a consequence of the acceleration of physiological ageing processes. Here, we compared the processes of physiological and pathological ageing in Caenorhabditis elegans. A multi-parametric approac
Autor:
Chee Wai Lee, Michael Currie, André Ex Brown, Eviatar Yemini, Avelino Javer, Ellen A. A. Nollen, Rex Kerr, Jim Hokanson, Quee-Lim Ch'ng, Chris Li, Laura J Grundy, Celine N. Martineau, William R Schafer, Kezhi Li
Publikováno v:
Nature Methods, 15(9), 645-646. Nature Publishing Group
Animal behavior is increasingly being recorded in systematic imaging studies that generate large data sets. To maximize the usefulness of these data there is a need for improved resources for analyzing and sharing behavior data that will encourage re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93e27f24305e6ba830a76f52a27e4c6
Autor:
Ido P. Kema, Helen Michels, Joost C.M. Uitdehaag, Celine N. Martineau, Mandy Koopman, Renée I. Seinstra, R.C. Buijsman, Martijn van Faassen, Ellen A. A. Nollen
Publikováno v:
Scientific Reports, 6:39199. Nature Publishing Group
Scientific Reports
Scientific Reports
The enzyme TDO (tryptophan 2,3-dioxygenase; TDO-2 in Caenorhabditis elegans) is a potential therapeutic target to cancer but is also thought to regulate proteotoxic events seen in the progression of neurodegenerative diseases. To better understand it