Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Celine Muldowney"'
Autor:
Wendy Jones, R. B. Pepinsky, Celine Muldowney, Laura Runkel, Susan Goelz, Werner Meier, K Kimball, Margot Brickelmaier, Michael Karpusas, Adrian Whitty
Publikováno v:
Pharmaceutical Research. 15:641-649
Purpose. Two recombinant IFN-β products have been approved for the treatment of multiple sclerosis, a glycosylated form with the predicted natural amino acid sequence (IFN-β-la) and a non-glycosylated form that has a Met-1 deletion and a Cys-17 to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24afec3267a6a7474217adcfcd702114
https://doi.org/10.1023/a:1011974512425
https://doi.org/10.1023/a:1011974512425
Autor:
Darren P. Baker, Carole de Dios, Zhifang Li, Celine Muldowney, Paula S. Hochman, Matthew Betzenhauser, Sidney E. Grossberg, Miller Stephan S, Philip N. Redlich, Laura Runkel, Michael Karpusas, Adrian Whitty, Mohammad Zafari
Publikováno v:
Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 21(11)
The epitopes important for receptor binding and activation of human interferon-beta1a (IFN-beta1a) were mapped with monoclonal antibodies (mAb), grouped on the basis of their specificity and ability to neutralize biologic activity, and alanine scanni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59e2fef4969aa29a93644da78e8c405
https://pubmed.ncbi.nlm.nih.gov/11747625
https://pubmed.ncbi.nlm.nih.gov/11747625
Autor:
Matthew Betzenhauser, Paula S. Hochman, Miller Stephan S, Mohammad Zafari, Laura Runkel, Celine Muldowney, Michael Karpusas, Adrian Whitty, Christopher D. Benjamin, Carole deDios
Publikováno v:
Biochemistry. 39(10)
A systematic mutational analysis of human interferon-beta-1a (IFN-beta) was performed to identify regions on the surface of the molecule that are important for receptor binding and for functional activity. The crystal structure of IFN-beta-1a was use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef6d4082370ddf37ff8ae13dbf3c2d3a
https://pubmed.ncbi.nlm.nih.gov/10704203
https://pubmed.ncbi.nlm.nih.gov/10704203