Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Celine Jacquemont"'
Autor:
Thomas F Gajewski, John A Thompson, Sanjay Goel, Brendan D Curti, Elisabeth I Heath, Olivier Rixe, David C Smith, Celine Jacquemont, Tycel Phillips, Martin Gutierrez, Sahar Ansari, Andrew L Coveler, Svetomir N Markovic, Timothy M Kuzel, Amitkumar N Mehta, David L Bajor, Hun Ju Lee, Ajay K Gopal, Paolo Caimi, Ariel Topletz-Erickson, Peigen Zhou, Michael W Schmitt, Juneko E Grilley-Olson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 6 (2023)
Background SEA-CD40 is an investigational, non-fucosylated, humanized monoclonal IgG1 antibody that activates CD40, an immune-activating tumor necrosis factor receptor superfamily member. SEA-CD40 exhibits enhanced binding to activating FcγRIIIa, po
Externí odkaz:
https://doaj.org/article/997d45d0420040f2a6abbe4400763c7d
Autor:
Naomi Hunder, Celine Jacquemont, Sarina Piha-Paul, Samuel Klempner, Valerie Odegard, John Strickler, Lindsey Gourley, Vinona Bhatia
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/9ed09fc8a23945a59be1777163338a2a
Autor:
Elizabeth Gray, Jeffrey Harris, Celine Jacquemont, Kelly Hensley, Sean Allred, Esther Trueblood, John Gosink, Robert Thurman, Kaleb Smith, Mark Bieda, Jason Gow, Lauren Brady, Ibrahima Soumaoro, Shweta Jain, Leonardo Nicacio
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/63930837eee04cd09b68aa1d96d40ddb
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/da855c2eba5046209c813624db008aad
Autor:
Philamer C. Calses, Kiranjit K. Dhillon, Nyka Tucker, Yong Chi, Jen-wei Huang, Masaoki Kawasumi, Paul Nghiem, Yemin Wang, Bruce E. Clurman, Celine Jacquemont, Philip R. Gafken, Kaoru Sugasawa, Masafumi Saijo, Toshiyasu Taniguchi
Publikováno v:
Cell Reports, Vol 19, Iss 1, Pp 162-174 (2017)
Ultraviolet (UV) radiation is a carcinogen that generates DNA lesions. Here, we demonstrate an unexpected role for DGCR8, an RNA binding protein that canonically functions with Drosha to mediate microRNA processing, in the repair of UV-induced DNA le
Externí odkaz:
https://doaj.org/article/d2a0ebcac7f646e3b21efe404b0f2b3c
Autor:
Maria Castella, Celine Jacquemont, Elizabeth L Thompson, Jung Eun Yeo, Ronald S Cheung, Jen-Wei Huang, Alexandra Sobeck, Eric A Hendrickson, Toshiyasu Taniguchi
Publikováno v:
PLoS Genetics, Vol 11, Iss 10, p e1005563 (2015)
The Fanconi anemia (FA)-BRCA pathway mediates repair of DNA interstrand crosslinks. The FA core complex, a multi-subunit ubiquitin ligase, participates in the detection of DNA lesions and monoubiquitinates two downstream FA proteins, FANCD2 and FANCI
Externí odkaz:
https://doaj.org/article/5fc9eb73ac664a3ba954e16d9d391c4c
Autor:
Kaleb Smith, Celine Jacquemont, Jeffrey R. Harris, Robert Thurman, Leonardo Viana Nicacio, John Gosink, Shyra Gardai, Esther Trueblood, Lauren Brady, I. Soumaoro, Jason Gow, Kelly Hensley, Mark Bieda, Shweta Jain, Sean Allred, Elizabeth Gray
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Tisotumab vedotin (TV) is an investigational antibody-drug conjugate composed of a tissue factor (TF)-directed human monoclonal antibody covalently linked to the microtubule-disrupting agent monomethyl auristatin E (MMAE) via a protease-cl
Autor:
Celine Jacquemont, John H. Strickler, Naomi Hunder, Vinona Bhatia, Lindsey Gourley, Valerie Odegard, Samuel J. Klempner, Sarina Anne Piha-Paul
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundSBT6050 is a novel therapeutic comprising a selective small molecule toll-like receptor 8 (TLR8) agonist linked to the HER2-directed monoclonal antibody pertuzumab, allowing for combination with trastuzumab-based agents and regimens. SBT605
Autor:
Olivier Rixe, Timothy M. Kuzel, David Smith, Martin Gutierrez, Sahar Ansari, John A. Thompson, Sanjay Goel, Andrew L. Coveler, Michael W. Schmitt, Thomas F. Gajewski, David L. Bajor, Haley Neff-LaFord, Shyra Gardai, Elisabeth I. Heath, Brendan D. Curti, Svetomir N. Markovic, Celine Jacquemont, Juneko E. Grilley-Olson
Publikováno v:
Cancer Research. 80:5535-5535
CD40 is a co-stimulatory receptor of the TNF receptor superfamily expressed on antigen presenting cells (APCs). Antibodies targeting CD40 may have therapeutic benefit via multiple mechanisms including innate immune activation that can support generat
Autor:
Heather A. Van Epps, Celine Jacquemont, James E. Hoffman, Hong Li, Yinghui Wang, Al-Ola Abdallah, Mark A. Schroeder, Mary S. Campbell
Publikováno v:
Journal of Clinical Oncology. 37:TPS8054-TPS8054
TPS8054 Background: Despite recent advances in treatment, multiple myeloma (MM) remains incurable in most patients. The standard of care for MM includes combinations of agents with different mechansims of action, e.g. proteasome inhibitors (PIs), imm