Výsledky vyhledávání - "Celine Franckhauser"

Akademický článek

NF90 interacts with components of RISC and modulates association of Ago2 with mRNA

Autor: Giuseppa Grasso, Charbel Akkawi, Celine Franckhauser, Rima Nait-Saidi, Maxime Bello, Jérôme Barbier, Rosemary Kiernan

Publikováno v: BMC Biology, Vol 20, Iss 1, Pp 1-14 (2022)

Abstract Background Nuclear factor 90 (NF90) is a double-stranded RNA-binding protein involved in a multitude of different cellular mechanisms such as transcription, translation, viral infection, and mRNA stability. Recent data suggest that NF90 migh

Externí odkaz: https://doaj.org/article/8750de79e87d45ddbb3dc2b2ea7d6bd0

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Akademický článek

Adult muscle-derived stem cells engraft and differentiate into insulin-expressing cells in pancreatic islets of diabetic mice

Autor: Violeta Mitutsova, Wendy Wai Yeng Yeo, Romain Davaze, Celine Franckhauser, El-Habib Hani, Syahril Abdullah, Patrice Mollard, Marie Schaeffer, Anne Fernandez, Ned J. C. Lamb

Publikováno v: Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-14 (2017)

Abstract Background Pancreatic beta cells are unique effectors in the control of glucose homeostasis and their deficiency results in impaired insulin production leading to severe diabetic diseases. Here, we investigated the potential of a population

Externí odkaz: https://doaj.org/article/5497ce5711d24500becfb3a0f2424c51

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Akademický článek

Characterization of the Akt2 domain essential for binding nuclear p21cip1 to promote cell cycle arrest during myogenic differentiation.

Autor: Lisa Heron-Milhavet, Celine Franckhauser, Anne Fernandez, Ned J Lamb

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e76987 (2013)

The binding of the cdk inhibitor p21cip1 to Akt2 in the nucleus is an essential component in determining the specific role of Akt2 in the cell cycle arrest that precedes myogenic differentiation. Here, through a combination of biochemical and cell bi

Externí odkaz: https://doaj.org/article/9f808c8d2f7140e19aae727881ab501d

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Akademický článek

Distinct pools of cdc25C are phosphorylated on specific TP sites and differentially localized in human mitotic cells.

Autor: Celine Franckhauser, Daria Mamaeva, Lisa Heron-Milhavet, Anne Fernandez, Ned J C Lamb

Publikováno v: PLoS ONE, Vol 5, Iss 7, p e11798 (2010)

BACKGROUND: The dual specificity phosphatase cdc25C was the first human cdc25 family member found to be essential in the activation of cdk1/cyclin B1 that takes place at the entry into mitosis. Human cdc25C is phosphorylated on Proline-dependent SP a

Externí odkaz: https://doaj.org/article/6230cb72b0ab4ac6af3011b5562add33

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NF90 Interacts with Components of RISC and Modulates Association of Ago2 with mRNA

Autor: Giuseppa Grasso, Charbel Akkawi, Celine Franckhauser, Rima Nait-Saidi, Maxime Bello, Jérôme Barbier, Rosemary Kiernan

Background Nuclear factor 90 (NF90) is a double-stranded RNA-binding protein involved in a multitude of different cellular mechanisms such as transcription, translation, viral infection, and mRNA stability. Recent data suggest that NF90 might influen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9898ddda9bfb601fd6d998e6e43a5bd0
https://doi.org/10.1101/2021.09.23.461467

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Chromatin-associated MRN complex protects highly transcribing genes from genomic instability

Autor: Celine Franckhauser, Poornima Basavarajaiah, Olivier Cuvier, Rosemary Kiernan, Victor Mac, Emmanuelle Beyne, Marion Helsmoortel, David Depierre, Jérôme Déjardin, Callum Burnard, Giuseppa Grasso, Sylvie Rouquier, Xavier Contreras, Kader Salifou

Publikováno v: Science Advances

Chromatin-associated MRN protects highly transcribing genes from genomic instability.
MRN-MDC1 plays a central role in the DNA damage response (DDR) and repair. Using proteomics of isolated chromatin fragments, we identified DDR factors, such as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155859723d2783f5349c8c2acb3d001f
https://doi.org/10.1101/2020.05.27.118638

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Identification of a New Hybrid Serum Response Factor and Myocyte Enhancer Factor 2-binding Element in MyoD Enhancer Required for MyoD Expression during Myogenesis

Autor: Aurore L'honoré, Vanessa Rana, Anne Fernandez, Celine Franckhauser, Ned J.C. Lamb, Nikola Arsic

Publikováno v: Molecular Biology of the Cell. 18:1992-2001

MyoD is a critical myogenic factor induced rapidly upon activation of quiescent satellite cells, and required for their differentiation during muscle regeneration. One of the two enhancers of MyoD, the distal regulatory region, is essential for MyoD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd5c0398bebd9d88dc4599c5a7d8fe7
https://doi.org/10.1091/mbc.e06-09-0867

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Purification and biochemical analysis of catalytically active human cdc25C dual specificity phosphatase

Autor: Anne Fernandez, Celine Franckhauser, Ned J.C. Lamb

Publikováno v: Biochimie
Biochimie, Elsevier, 2013, 95 (7), pp.1450-1461. ⟨10.1016/j.biochi.2013.03.011⟩

We describe a reliable and efficient method for the purification of catalytically active and mutant inactive full-length forms of the human dual specificity phosphatase cdc25C from bacteria. The protocol involves isolating insoluble cdc25C protein in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e883cf585a2394469f89e1101180cc
https://hal.archives-ouvertes.fr/hal-00852761

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Characterization of the Akt2 Domain Essential for Binding Nuclear p21cip1 to Promote Cell Cycle Arrest during Myogenic Differentiation

Autor: Celine Franckhauser, Ned J.C. Lamb, Anne Fernandez, Lisa Heron-Milhavet

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2013, 8 (10), pp.e76987. ⟨10.1371/journal.pone.0076987⟩
PLoS ONE, 2013, 8 (10), pp.e76987. ⟨10.1371/journal.pone.0076987⟩
PLoS ONE, Vol 8, Iss 10, p e76987 (2013)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440b4f310a2616e45480eea6959e3857
https://hal.archives-ouvertes.fr/hal-00906356

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The cell cycle control protein cdc25C is present and phosphorylated on serine 214 in the transition from germinal vesicle to metaphase II in human oocyte meiosis

Autor: B. Hedon, Anne Fernandez, S. Hamamah, S. Cunat, Cyril Berthenet, Celine Franckhauser, Ned J.C. Lamb, T. Anahory

Publikováno v: Molecular Reproduction and Development
Molecular Reproduction and Development, Wiley, 2008, 75 (7), pp.1176-1184. ⟨10.1002/mrd.20853⟩

Cdc25C is a dual specificity phosphatase essential for dephosphorylation and activation of cyclin-dependent kinase 1 (cdk1), a prerequisite step for mitosis in all eucaryotes. Cdc25C activation requires phosphorylation on at least six sites including

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25bfe64bc80b3d595ed2cfd95a7e2670
https://hal.archives-ouvertes.fr/hal-00287914

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