Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Celine Denais"'
Autor:
Elizabeth F. Maughan, Robert E. Hynds, Adam Pennycuick, Ersilia Nigro, Kate H.C. Gowers, Celine Denais, Sandra Gómez-López, Kyren A. Lazarus, Jessica C. Orr, David R. Pearce, Sarah E. Clarke, Dani Do Hyang Lee, Maximillian N.J. Woodall, Tereza Masonou, Katie-Marie Case, Vitor H. Teixeira, Benjamin E. Hartley, Richard J. Hewitt, Chadwan Al Yaghchi, Gurpreet S. Sandhu, Martin A. Birchall, Christopher O’Callaghan, Claire M. Smith, Paolo De Coppi, Colin R. Butler, Sam M. Janes
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105409- (2022)
Summary: The airway epithelium is a protective barrier that is maintained by the self-renewal and differentiation of basal stem cells. Increasing age is a principle risk factor for chronic lung diseases, but few studies have explored age-related mole
Externí odkaz:
https://doaj.org/article/bc9bfc65a4564f5b8c32bca349dccceb
Autor:
Sam M. Janes, Nicholas McGranahan, Sergio A. Quezada, Yinyin Yuan, Teresa Marafioti, Peter J. Campbell, Christina Thirlwell, Charles Swanton, Jeremy George, Ricky M. Thakrar, Lisa M. Coussens, Courtney Betts, William Larson, Marie-Liesse Asselin-Labat, Claire Marceaux, Bernadette Carroll, Andrew J. Furness, Pascal F. Durrenberger, Sophia Antoniou, David A. Moore, Mary Falzon, Celine Denais, Yeman B. Hagos, Fraser R. Millar, Jake Y. Henry, Kate H.C. Gowers, Robert E. Hynds, Henry Lee-Six, Christodoulos P. Pipinikas, Deepak P. Chandrasekharan, Lukas Kalinke, Rachel Rosenthal, Ayse U. Akarca, Tom Lund, Shan E. Ahmed Raza, Khalid AbdulJabbar, Vitor H. Teixeira, Adam Pennycuick
Immune cell deconvolution from molecular data. Relative proportions of immune cell subtypes are predicted from gene expression data using the Danaher method, and from methylation data using methylCIBERSORT. Differences between progressive and regress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0408e249465611db42368906c8f88642
https://doi.org/10.1158/2159-8290.22536935.v1
https://doi.org/10.1158/2159-8290.22536935.v1
Autor:
Sam M. Janes, Nicholas McGranahan, Sergio A. Quezada, Yinyin Yuan, Teresa Marafioti, Peter J. Campbell, Christina Thirlwell, Charles Swanton, Jeremy George, Ricky M. Thakrar, Lisa M. Coussens, Courtney Betts, William Larson, Marie-Liesse Asselin-Labat, Claire Marceaux, Bernadette Carroll, Andrew J. Furness, Pascal F. Durrenberger, Sophia Antoniou, David A. Moore, Mary Falzon, Celine Denais, Yeman B. Hagos, Fraser R. Millar, Jake Y. Henry, Kate H.C. Gowers, Robert E. Hynds, Henry Lee-Six, Christodoulos P. Pipinikas, Deepak P. Chandrasekharan, Lukas Kalinke, Rachel Rosenthal, Ayse U. Akarca, Tom Lund, Shan E. Ahmed Raza, Khalid AbdulJabbar, Vitor H. Teixeira, Adam Pennycuick
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c889c181198e05bf5aa948da6e69f5d
https://doi.org/10.1158/2159-8290.22536944.v1
https://doi.org/10.1158/2159-8290.22536944.v1
Autor:
Sam M. Janes, Nicholas McGranahan, Sergio A. Quezada, Yinyin Yuan, Teresa Marafioti, Peter J. Campbell, Christina Thirlwell, Charles Swanton, Jeremy George, Ricky M. Thakrar, Lisa M. Coussens, Courtney Betts, William Larson, Marie-Liesse Asselin-Labat, Claire Marceaux, Bernadette Carroll, Andrew J. Furness, Pascal F. Durrenberger, Sophia Antoniou, David A. Moore, Mary Falzon, Celine Denais, Yeman B. Hagos, Fraser R. Millar, Jake Y. Henry, Kate H.C. Gowers, Robert E. Hynds, Henry Lee-Six, Christodoulos P. Pipinikas, Deepak P. Chandrasekharan, Lukas Kalinke, Rachel Rosenthal, Ayse U. Akarca, Tom Lund, Shan E. Ahmed Raza, Khalid AbdulJabbar, Vitor H. Teixeira, Adam Pennycuick
Before squamous cell lung cancer develops, precancerous lesions can be found in the airways. From longitudinal monitoring, we know that only half of such lesions become cancer, whereas a third spontaneously regress. Although recent studies have descr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a98571a5212598e8738475feb59ae69d
https://doi.org/10.1158/2159-8290.c.6548276.v1
https://doi.org/10.1158/2159-8290.c.6548276.v1
Autor:
Christodoulos P. Pipinikas, Ricky Thakrar, Sergio A. Quezada, Vitor H. Teixeira, Sophia Antoniou, Adam Pennycuick, Jeremy George, Lukas Kalinke, Yinyin Yuan, Robert E. Hynds, Henry Lee-Six, Sam M. Janes, Fraser R. Millar, Celine Denais, Shan E Ahmed Raza, Andrew Furness, Jake Y. Henry, Nicholas McGranahan, Ayse Akarca, Christina Thirlwell, Claire Marceaux, Yeman Brhane Hagos, Lisa M. Coussens, Pascal F. Durrenberger, Marie Liesse Asselin-Labat, Peter J. Campbell, Charles Swanton, Khalid AbdulJabbar, Teresa Marafioti, Rachel Rosenthal, Deepak P. Chandrasekharan, Tom Lund, Kate H.C. Gowers, David A Moore, Mary Falzon, Bernadette Carroll, William Larson, Courtney Betts
Before squamous cell lung cancer develops, precancerous lesions can be found in the airways. From longitudinal monitoring, we know that only half of such lesions become cancer, whereas a third spontaneously regress. Although recent studies have descr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81c77375f391eea8fda27722adc7253b
http://wrap.warwick.ac.uk/139480/7/WRAP-Immune-surveillance-clinical-regression-pre-invasive-squamous-cell-lung-cancer-Raza-2020.pdf
http://wrap.warwick.ac.uk/139480/7/WRAP-Immune-surveillance-clinical-regression-pre-invasive-squamous-cell-lung-cancer-Raza-2020.pdf
Autor:
Shan E Ahmed Raza, Tom Lund, Mary Falzon, Christina Thirlwell, Yinyin Yuan, P J George, Deepak P. Chandrasekharan, Vitor H. Teixeira, Bernadette Carroll, Christodoulos P. Pipinikas, Jake Y. Henry, Celine Denais, Henry Lee-Six, Sam M. Janes, Robert E. Hynds, Nicholas McGranahan, Adam Pennycuick, Sophia Antoniou, Andrew Furness, Ricky Thakrar, Sergio A. Quezada, Pascal F. Durrenberger, Peter J. Campbell, Khalid AbdulJabbar, Ayse Akarca, Kate H.C. Gowers, Charles Swanton, Teresa Marafioti, Rachel Rosenthal
Before squamous cell lung cancer develops, pre-cancerous lesions can be found in the airways. From longitudinal monitoring, we know that only half of such lesions become cancer, whereas a third spontaneously regress. While recent studies have describ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c96b42f2fd0c63e11e4ddf87e88bd639
Autor:
Katarina Wolf, Alexandra L. McGregor, Celine Denais, Patricia M. Davidson, Philipp Isermann, Rachel M. Gilbert, Jan Lammerding, Peter Friedl, Mariska te Lindert, Bettina Weigelin
Publikováno v:
Science, 352, 353-8
Science, 352, 6283, pp. 353-8
Science, 352, 6283, pp. 353-8
Repairing tears in the nuclear envelope The nuclear envelope segregates genomic DNA from the cytoplasm and regulates protein trafficking between the cytosol and the nucleus. Maintaining nuclear envelope integrity during interphase is considered cruci
Autor:
Harihara Baskaran, Yu-li Wang, William P. Schiemann, Dustin Thomas, Aishwarya Yenepalli, Jordan R. Beach, Jan Lammerding, Andrew D. Rape, Celine Denais, Thomas T. Egelhoff
Publikováno v:
The Journal of Cell Biology
Non-muscle myosin IIB plays a major role in applying force on the nucleus to facilitate nuclear translocation through tight spaces during 3D invasive migration, while non-muscle myosin IIA is critical for generating force during active protrusion.
Publikováno v:
Integrative Biology. 7:1534-1546
The ability of cells to migrate through tissues and interstitial spaces is an essential factor during development and tissue homeostasis, immune cell mobility, and in various human diseases. Deformation of the nucleus and its associated lamina during
Autor:
Jacqueline Hoyle, Carolyn L. Dent, Laura Southgate, Celine Denais, Dimitra Dafou, Richard C. Trembath, Rajiv D. Machado
Publikováno v:
Human Mutation. 32:231-239
Dyggve-Melchior-Clausen syndrome (DMC), a severe autosomal recessive skeletal disorder with mental retardation, is caused by mutation of the gene encoding Dymeclin (DYM). Employing patient fibroblasts with mutations characterized at the genomic and,