Výsledky vyhledávání - "Celine A. Blache"

The effect of soluble E-selectin on tumor progression and metastasis

Autor: Bilegtsaikhan Tsolmon, Hallgeir Rui, Vineet Gupta, Celine A. Blache, Takemi Tanaka, Yoshihiro Morita, David G. Gorenstein, Stephen K. Suh, Shin Ae Kang, Mohamed Kamal, Sandra Bajana, Nafis Hasan, Wajeeha Razaq

Publikováno v: BMC Cancer

Background Distant metastasis resulting from vascular dissemination of cancer cells is the primary cause of mortality from breast cancer. We have previously reported that E-selectin expression on the endothelial cell surface mediates shear-resistant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebaef4a1ce30f12ce9ceafd83abe44f5
http://europepmc.org/articles/PMC4879723

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Systemic Delivery of Salmonella typhimurium Transformed with IDO shRNA Enhances Intratumoral Vector Colonization and Suppresses Tumor Growth

Autor: Celine A. Blache, Andrea N. Wong, Edwin R. Manuel, Don J. Diamond, Joshua D. I. Ellenhorn, Teodora Kaltcheva, Bruce R. Blazar

Publikováno v: Cancer Research. 72:6447-6456

Generating antitumor responses through the inhibition of tumor-derived immune suppression represents a promising strategy in the development of cancer immunotherapeutics. Here, we present a strategy incorporating delivery of the bacterium Salmonella

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::741868b2fc14e7185502148f76e29c82
https://doi.org/10.1158/0008-5472.can-12-0193

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Number and phenotype of rheumatoid arthritis patients’ CD4+CD25hi regulatory T cells are not affected by adalimumab or etanercept

Autor: Serge Jacquot, Celine A. Blache, Ingrid Dedreux, Olivier Vittecoq, Arnaud Roucheux, Thierry Lequerré, Xavier Le Loët, Olivier Boyer, Stéphanie Beutheu

Publikováno v: Rheumatology. 50:1814-1822

Objective To analyse the therapeutic effects of etanercept (ETA) or adalimumab (ADA) on the numbers and phenotypes of CD4+CD25hi Tregs in RA patients. Methods RA patients received ADA (n = 28) or ETA (n = 20) and stable-dose MTX or LEF. Therapeutic r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61bbab0d43d2b1ab9b2d2e7feeecf147
https://doi.org/10.1093/rheumatology/ker183

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Characterization of the transcriptional signature of C/EBPbeta isoforms (LAP/LIP) in Hep3B cells: Implication of LIP in pro-survival functions

Autor: Xavier Gidrol, Jean-Louis Danan, Eric Sulpice, Martine Hiron, Jean-Philippe Salier, Simon Tendil, Gaëlle Saint-Auret, Maryvonne Daveau, Celine A. Blache

Publikováno v: Journal of Hepatology. 54:1185-1194

Background & Aims C/EBPbeta is an important mediator of several cellular processes, such as differentiation, proliferation, and survival of hepatic cells. However, a complete catalog of the targets of C/EBPbeta or the mechanism by which this transcri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edc08529e34b2569cada1b50b8cb8248
https://doi.org/10.1016/j.jhep.2010.09.021

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Cutting edge: CD4-independent development of functional FoxP3+ regulatory t cells

Autor: Sahil Adriouch, Adrien Six, Laurent Drouot, Christophe Arnoult, Sébastien Calbo, Olivier Boyer, Michel Seman, Stéphanie Le Corre, Sophie Dulauroy, Celine A. Blache

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2009, 183 (7), pp.4182-6. ⟨10.4049/jimmunol.0901678⟩
Journal of Immunology, 2009, 183 (7), pp.4182-6. ⟨10.4049/jimmunol.0901678⟩

The CD4 coreceptor is mandatory for the differentiation and function of conventional MHC class II-restricted T cells, but little is known about its contribution in regulatory T cells (Tregs). We thus investigated the Treg compartment in mice lacking

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af17fb1daad444244be5b1ae010ba315
https://hal.archives-ouvertes.fr/hal-00420220

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Reduced frequency of regulatory T cells in peripheral blood stem cell compared to bone marrow transplantations

Autor: Ingrid Dedreux, Nathalie Contentin, Olivier Boyer, Celine A. Blache, Dominique Bastit, Stéphanie François, Pascal Pommier, Aude Marie-Cardine, Joe-Marc Chauvin, Serge Jacquot

Publikováno v: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 16(3)

Peripheral blood stem cell transplantation (PBSCT) is an alternative to bone marrow transplantation (BMT). Although CD4(+)CD25(+)CD127(lo) regulatory T cells (Tregs) have been shown to play important roles in the control of T cell reactivity, the Tre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2020d88b1261d67e871a05a10bc89cb6
https://pubmed.ncbi.nlm.nih.gov/19883775

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Abstract 4992: A novel role of soluble E-selectin as a chemoatractant to human leukocytes through the PI3kinase signaling pathway in breast cancer

Autor: Takemi Tanaka, Hallgeir Rui, Celine A. Blache, David G. Gorenstein, Nafis Hasan, Stephen K. Suh, Jeehna Park

Publikováno v: Cancer Research. 73:4992-4992

Solid tumors are multicellular complexes where the tumor stroma that is comprised of endothelial cells, pericytes, fibroblasts and immune cells, all of which orchestrate to assist in cancer cell growth, angiogenesis and invasion. The tissue infiltrat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::19f9ace4ec381bf44d793e23bf91791c
https://doi.org/10.1158/1538-7445.am2013-4992

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Expression and detection strategies for an scFv fragment retaining the same high affinity than Fab and whole antibody: Implications for therapeutic use in prion diseases

Autor: Sosthène Essono, Fatima Dkhissi, Séverine Padiolleau-Lefevre, Jean-Yves Couraud, Coralie Alexandrenne, Anne Wijkhuisen, Didier Boquet, Gilles Clément, Celine A. Blache

Publikováno v: Molecular Immunology
Molecular Immunology, Elsevier, 2007, 44 (8), pp.1888-1896. ⟨10.1016/j.molimm.2006.09.035⟩
Molecular Immunology, 2007, 44 (8), pp.1888-1896. ⟨10.1016/j.molimm.2006.09.035⟩

Since antibodies currently constitute the most rapidly growing class of human therapeutics, the high-yield production of recombinant antibodies and antibody fragments is a real challenge. Using as model a monoclonal antibody directed against the huma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a7ad5989dc84a37fee41d558d471c1
https://pubmed.ncbi.nlm.nih.gov/17140664

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Survivin the battle against immunosuppression

Autor: Joshua D. I. Ellenhorn, Celine A. Blache, Edwin R. Manuel, Don J. Diamond

Publikováno v: Oncoimmunology

Improving on the limited success of cancer immunotherapy requires new approaches to inhibit immunosuppressive pathways initiated by tumor cells to “escape” protective immunity. One unique approach utilizes Salmonella for systemic delivery of inhi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c5287c8f3af44bdb14ccdddd2a7c9fb
http://europepmc.org/articles/PMC3377007

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Erratum to: The effect of soluble E-selectin on tumor progression and metastasis

Autor: Mohamed Kamal, David G. Gorenstein, Sandra Bajana, Vineet Gupta, Bilegtsaikhan Tsolmon, Takemi Tanaka, Hallgeir Rui, Nafis Hasan, Celine A. Blache, K. Stephen Suh, Shin Ae Kang, Wajeeha Razaq, Yoshihiro Morita

Publikováno v: BMC Cancer

Distant metastasis resulting from vascular dissemination of cancer cells is the primary cause of mortality from breast cancer. We have previously reported that E-selectin expression on the endothelial cell surface mediates shear-resistant adhesion an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af6aa48b6b5cab04862d602506b4bcfd

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