Absence of ERK5/MAPK7 delays tumorigenesis in Atm−/− mice by Granados-Jaén, et al. Oncotarget. 2016; 7(46):74435-74447. doi: 10.18632/oncotarget.12908

Autor: Alba Granados-Jaén, Enric Espel, Celina Paola Vasquez Gamez, Maria Angulo-Ibáñez, Francesc X. Soriano, Manuel Reina, Xavier Rovira-Clavé

Publikováno v: Oncotarget
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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Recercat. Dipósit de la Recerca de Catalunya
Dipòsit Digital de la UB
Universidad de Barcelona

Ataxia-telangiectasia mutated (ATM) is a cell cycle checkpoint kinase that upon activation by DNA damage leads to cell cycle arrest and DNA repair or apoptosis. The absence of Atm or the occurrence of loss-of-function mutations in Atm predisposes to

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