Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Celina Ang"'
Autor:
Lorenz Balcar, Bernhard Scheiner, Claudia Angela Maria Fulgenzi, Antonio D’Alessio, Katharina Pomej, Marta Bofill Roig, Elias Laurin Meyer, Jaekyung Che, Naoshi Nishida, Pei-Chang Lee, Linda Wu, Celina Ang, Anja Krall, Anwaar Saeed, Bernardo Stefanini, Antonella Cammarota, Tiziana Pressiani, Yehia I. Abugabal, Shadi Chamseddine, Brooke Wietharn, Alessandro Parisi, Yi-Hsiang Huang, Samuel Phen, Caterina Vivaldi, Francesca Salani, Gianluca Masi, Dominik Bettinger, Arndt Vogel, Johann von Felden, Kornelius Schulze, Marianna Silletta, Michael Trauner, Adel Samson, Henning Wege, Fabio Piscaglia, Peter R. Galle, Rudolf Stauber, Masatoshi Kudo, Amit G. Singal, Aleena Itani, Susanna V. Ulahannan, Neehar D. Parikh, Alessio Cortellini, Ahmed Kaseb, Lorenza Rimassa, Hong Jae Chon, David J. Pinato, Matthias Pinter
Publikováno v:
JHEP Reports, Vol 6, Iss 2, Pp 100982- (2024)
Background & Aims: Sex-related differences in the immune pathogenesis of hepatocellular carcinoma (HCC), particularly related to oestrogen-dependent secretion of pro-tumourigenic cytokines, are well-known. Whether sex influences the efficacy and safe
Externí odkaz:
https://doaj.org/article/a0a6b9404c43458295dafe7f3cb32ed2
Autor:
Noam Harpaz, Samarth Hegde, Lisa Fitzgerald, Stephen Ward, Miriam Merad, Thomas Marron, Zheng Zhu, Qingqing Liu, Celina Ang, Deborah Doroshow, Umut Sarpel, Kathy Wu, Ana Acuna-Villaorduna, Natalie Lucas, Nicholas Venturini, Raphaël Mattiuz, Clotilde Hennequin, Jessica Le Berichel, Theodore Chin, Amanda Reid, Leanna Troncoso, David Greenwald, Ari Grinspan, Steve Itzkowitz, Aimee L Lucas, Dana Zalkin, Peter Kozuch, Sergey Khaitov, Alex Ky-Miyasaka, Randolph Steinhagen, Patricia Sylla, Gunther Kretschmar, John Paulsen, Xintong Wang, Alexandros D Polydorides, Deirdre Cohen, Gabriela Fazilov, Gary Shelton, Amber Cameron, Megan Yuan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/f4976598fe474b3bbabfbc038fa62732
Patterns and outcomes of subsequent therapy after immune checkpoint inhibitor discontinuation in HCC
Autor:
Rohini Sharma, Anjana Pillai, Thomas Urban Marron, Petros Fessas, Anwaar Saeed, Tomi Jun, Sirish Dharmapuri, David Szafron, Abdul Rafeh Naqash, Anuhya Gampa, Yinghong Wang, Uqba Khan, Mahvish Muzaffar, Chieh‐Ju Lee, Pei‐Chang Lee, Anushi Bulumulle, Sonal Paul, Dominic Bettinger, Hannah Hildebrand, Mohammed Yehia, Tiziana Pressiani, Ahmed Kaseb, Yi‐Hsiang Huang, Celina Ang, Masatoshi Kudo, Naoshi Nishida, Nicola Personeni, Lorenza Rimassa, David James Pinato
Publikováno v:
Hepatology Communications, Vol 6, Iss 7, Pp 1776-1785 (2022)
Abstract The availability of immune checkpoint inhibitors (ICIs) for the management of advanced hepatocellular cancer (HCC) has changed the treatment paradigm. There are emerging questions regarding the efficacy of subsequent anticancer therapies. Th
Externí odkaz:
https://doaj.org/article/e44c4fda0f48434e9cdc4675c1f8ec5f
Autor:
Y. Linda Wu, Grace van Hyfte, Umut Özbek, Marlene Reincke, Anuhya Gampa, Yehia I. Mohamed, Naoshi Nishida, Brooke Wietharn, Suneetha Amara, Pei-Chang Lee, Bernhard Scheiner, Lorenz Balcar, Matthias Pinter, Arndt Vogel, Arndt Weinmann, Anwaar Saeed, Anjana Pillai, Lorenza Rimassa, Abdul Rafeh Naqash, Mahvish Muzaffar, Yi-Hsiang Huang, Ahmed O. Kaseb, Masatoshi Kudo, David J. Pinato, Celina Ang
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundIn patients with cirrhosis, portal hypertension increases intestinal permeability, dysbiosis, and bacterial translocation, promoting an inflammatory state that can lead to the progression of liver disease and development of hepatocellular c
Externí odkaz:
https://doaj.org/article/5885bcec7b444fc4b4fe6d9c281e9f99
Autor:
Petros Fessas, Muntaha Naeem, Matthias Pinter, Thomas U. Marron, David Szafron, Lorenz Balcar, Anwaar Saeed, Tomi Jun, Sirish Dharmapuri, Anuhya Gampa, Yinghong Wang, Uqba Khan, Mahvish Muzaffar, Musharraf Navaid, Pei-Chang Lee, Anushi Bulumulle, Bo Yu, Sonal Paul, Neil Nimkar, Dominik Bettinger, Hannah Hildebrand, Yehia I. Abugabal, Tiziana Pressiani, Nicola Personeni, Naoshi Nishida, Masatoshi Kudo, Ahmed Kaseb, Yi-Hsiang Huang, Celina Ang, Anjana Pillai, Lorenza Rimassa, Abdul Rafeh Naqash, Elad Sharon, Alessio Cortellini, David J. Pinato
Publikováno v:
Liver Cancer, Vol 10, Iss 6, Pp 583-592 (2021)
Background and Rationale: Immune checkpoint inhibitor (ICI) therapy is an expanding therapeutic option for hepatocellular carcinoma (HCC). Antibiotics (ATB) taken prior to or early during ICI therapy can impact immunotherapy efficacy across indicatio
Externí odkaz:
https://doaj.org/article/5b2616ec247c4eb78946d132559d4210
Autor:
Dominik Bettinger, Masatoshi Kudo, Abdul Rafeh Naqash, Mahvish Muzaffar, Thomas Marron, Uqba Khan, Myron Schwartz, Yi-Hsiang Huang, David J Pinato, Anwaar Saeed, Hannah Hildebrand, Yehia I Abugabal, Celina Ang, Rahul Patel, Edward Kim, Naoshi Nishida, Ahmed O Kaseb, Anjana Pillai, Neha Debnath, Antonio D'Alessio, Brett Marinelli, Mario Cedillo, Ishan Sinha, Aaron Fischman, Vivian Bishay, Max Sung
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/adcd789e88fc4bc891885ba3230180a2
Autor:
Yue Linda Wu, Claudia Angela Maria Fulgenzi, Antonio D’Alessio, Jaekyung Cheon, Naoshi Nishida, Anwaar Saeed, Brooke Wietharn, Antonella Cammarota, Tiziana Pressiani, Nicola Personeni, Matthias Pinter, Bernhard Scheiner, Lorenz Balcar, Yi-Hsiang Huang, Samuel Phen, Abdul Rafeh Naqash, Caterina Vivaldi, Francesca Salani, Gianluca Masi, Dominik Bettinger, Arndt Vogel, Martin Schönlein, Johann von Felden, Kornelius Schulze, Henning Wege, Peter R. Galle, Masatoshi Kudo, Lorenza Rimassa, Amit G. Singal, Rohini Sharma, Alessio Cortellini, Vincent E. Gaillard, Hong Jae Chon, David J. Pinato, Celina Ang
Publikováno v:
Cancers, Vol 14, Iss 23, p 5834 (2022)
Systemic inflammation is a key risk factor for hepatocellular carcinoma (HCC) progression and poor outcomes. Inflammatory markers such as the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) may have prognostic value in HCC
Externí odkaz:
https://doaj.org/article/2bd209b5c480422bb49139635dbd2602
Autor:
Sheena Bhalla, Huili Zhu, Jung‐Yi Lin, Umut Özbek, Eric J. Wilck, Sanders Chang, Xiuxu Chen, Stephen Ward, Noam Harpaz, Alexandros D. Polydorides, William Miller, Maria Isabel Fiel, Ippolito Modica, Wen Fan, Nebras Zeizafoun, Celina Ang
Publikováno v:
Cancer Reports, Vol 4, Iss 6, Pp n/a-n/a (2021)
Abstract Background Neoadjuvant chemotherapy (NAC) is frequently used in gastrointestinal cancers (GIC), and pathological, radiological, and tumor marker responses are assessed during and after NAC. Aim To evaluate the relationship between pathologic
Externí odkaz:
https://doaj.org/article/1bdbe2c8a4f84eac9d655c81b2b4d045
Autor:
Sirish Dharmapuri, Umut Özbek, Jung‐Yi Lin, Max Sung, Myron Schwartz, Andrea D. Branch, Celina Ang
Publikováno v:
Cancer Medicine, Vol 9, Iss 14, Pp 4962-4970 (2020)
Abstract Background Currently, there are no recognized or validated biomarkers to identify hepatocellular carcinoma patients (HCC) likely to benefit from anti–PD‐1 therapy. We evaluated the relationship between neutrophil‐lymphocyte ratio (NLR)
Externí odkaz:
https://doaj.org/article/7c330b359e9948eba7e3dffe2622693f
Autor:
Tomi Jun, Umut Ozbek, Sirish Dharmapuri, Camille Hardy-Abeloos, Huili Zhu, Jung-Yi Lin, Nicola Personeni, Tiziana Pressiani, Naoshi Nishida, Pei-Chang Lee, Chieh-Ju Lee, Hannah Hildebrand, Neil Nimkar, Sonal Paul, Petros Fessas, Muntaha Naeem, Dominik Bettinger, Uqba Khan, Anwaar Saeed, Yi-Hsiang Huang, Masatoshi Kudo, Lorenza Rimassa, Thomas U. Marron, David J. Pinato, Celina Ang
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Background: Antibiotic exposure has been associated with worse outcomes with immune checkpoint inhibitors (ICIs) in cancer patients, likely due to disruption of the gut microbiome. Other commonly prescribed medications, such as proton pump inhibitors
Externí odkaz:
https://doaj.org/article/2cd3809960ca4aa790944f7a51d499a1