Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Celia Murciano"'
Autor:
Jemima Ho, Xuexin Yang, Spyridoula-Angeliki Nikou, Nessim Kichik, Andrew Donkin, Nicole O. Ponde, Jonathan P. Richardson, Remi L. Gratacap, Linda S. Archambault, Christian P. Zwirner, Celia Murciano, Rhonda Henley-Smith, Selvam Thavaraj, Christopher J. Tynan, Sarah L. Gaffen, Bernhard Hube, Robert T. Wheeler, David L. Moyes, Julian R. Naglik
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Candida albicans is an opportunistic fungus primarily affecting immunocompromised patients. Here, the authors identify a novel mechanism of host immune stimulation and highlight candidalysin and EGFR signalling components as potential targets for pro
Externí odkaz:
https://doaj.org/article/5a35ef4f63da4f5da3fd3d4b2fc4fa96
Autor:
Arinder Kohli, Ayesha Islam, David L Moyes, Celia Murciano, Chengguo Shen, Stephen J Challacombe, Julian R Naglik
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0229553 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0098077.].
Externí odkaz:
https://doaj.org/article/ff66cf5cf5b948d0a770c3e7de12ca09
Autor:
Celia Murciano, Chung-Te Lee, Ana Fernández-Bravo, Tsung-Han Hsieh, Belén Fouz, Lien-I Hor, Carmen Amaro
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Vibrio vulnificus biotype 2-serovar E is a zoonotic clonal complex that can cause death by sepsis in humans and fish. Unlike other biotypes, Bt2 produces a unique type of MARTXVv (Multifunctional-Autoprocessive-Repeats-in-Toxin; RtxA13), which is enc
Externí odkaz:
https://doaj.org/article/0e1f85080c6c49c0813cbba6e0b2ab7d
Autor:
Arinder Kohli, Ayesha Islam, David L Moyes, Celia Murciano, Chengguo Shen, Stephen J Challacombe, Julian R Naglik
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98077 (2014)
The majority of HIV-1 infections worldwide are acquired via mucosal surfaces. However, unlike the vaginal mucosa, the issue of whether the oral mucosa can act as a portal of entry for HIV-1 infection remains controversial. To address potential differ
Externí odkaz:
https://doaj.org/article/41d1cb63f7304dc796d87a7b3de43338
Autor:
Celia Murciano, David L Moyes, Manohursingh Runglall, Priscila Tobouti, Ayesha Islam, Lois L Hoyer, Julian R Naglik
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33362 (2012)
The fungus C. albicans uses adhesins to interact with human epithelial surfaces in the processes of colonization and pathogenesis. The C. albicans ALS (agglutinin-like sequence) gene family encodes eight large cell-surface glycoproteins (Als1-Als7 an
Externí odkaz:
https://doaj.org/article/b08352c1291942889d6791f93e83bc13
Autor:
David L Moyes, Celia Murciano, Manohursingh Runglall, Ayesha Islam, Selvam Thavaraj, Julian R Naglik
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e26580 (2011)
We previously reported that a bi-phasic innate immune MAPK response, constituting activation of the mitogen-activated protein kinase (MAPK) phosphatase MKP1 and c-Fos transcription factor, discriminates between the yeast and hyphal forms of Candida a
Externí odkaz:
https://doaj.org/article/d296f7ba9fb94cbc934e373798298243
Publikováno v:
Journal of Plant Science and Phytopathology. 5:044-052
During the 2018 season, superficial dry and firm black spots, where sometimes an aerial mycelium developed, appeared on the rind of easy peeler mandarins causing high economic losses in fresh citrus exports from Perú. In this work, we have identifie
Immune responses to Candida albicans involve recognition of fungal ligands (pathogen-associated molecular patterns (PAMPs)) by pattern recognition receptors (PRRs) on a variety of immune cells that trigger a complex and coordinated network of timely/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33aea560170326c272070af1711a7784
https://doi.org/10.1016/b978-0-12-809633-8.12075-8
https://doi.org/10.1016/b978-0-12-809633-8.12075-8
Autor:
Simona Ioana Iancu, Shirley X. Tang, Manohursingh Runglall, Antje Häder, Julian R. Naglik, Betty Hebecker, Toni M. Förster, Duncan Wilson, Robert T. Wheeler, Remi L. Gratacap, Jon Robbins, Oliver Bader, Sarah Höfs, Ernesto Cota, Gema Vizcay, Jonathan P. Richardson, Nessim Kichik, Mariana Blagojevic, Ting Luo, Olaf Kniemeyer, Julia Wernecke, Bernhard Hube, Thomas Krüger, David L. Moyes, Selene Mogavero, Celia Murciano, Lydia Kasper, Oliver Kurzai, Thomas Gutsmann, Selvam Thavaraj
Publikováno v:
Nature 532(7597), 64-68 (2016). doi:10.1038/nature17625
Nature
Moyes, D L, Wilson, D, Richardson, J P, Mogavero, S, Tang, S X, Wernecke, J, Hofs, S, Gratacap, R L, Robbins, J, Runglall, M, Murciano, C, Blagojevic, M, Thavaraj, S, Forster, T M, Hebecker, B, Kasper, L, Vizcay-Barrena, G, Iancu, S I, Kichik, N, Hader, A, Kurzai, O, Luo, T, Kruger, T, Kniemeyer, O, Cota, E, Bader, O, Bader, O, Wheeler, R T, Gutsmann, T, Hube, B & Naglik, J R 2016, ' Candidalysin is a fungal peptide toxin critical for mucosal infection ', NATURE, vol. 532, no. 7597, pp. 64-68 . https://doi.org/10.1038/nature17625
Nature
Moyes, D L, Wilson, D, Richardson, J P, Mogavero, S, Tang, S X, Wernecke, J, Hofs, S, Gratacap, R L, Robbins, J, Runglall, M, Murciano, C, Blagojevic, M, Thavaraj, S, Forster, T M, Hebecker, B, Kasper, L, Vizcay-Barrena, G, Iancu, S I, Kichik, N, Hader, A, Kurzai, O, Luo, T, Kruger, T, Kniemeyer, O, Cota, E, Bader, O, Bader, O, Wheeler, R T, Gutsmann, T, Hube, B & Naglik, J R 2016, ' Candidalysin is a fungal peptide toxin critical for mucosal infection ', NATURE, vol. 532, no. 7597, pp. 64-68 . https://doi.org/10.1038/nature17625
Cytolytic proteins and peptide toxins are classical virulence factors of several bacterial pathogens which disrupt epithelial barrier function, damage cells and activate or modulate host immune responses. Such toxins have not been identified previous
Autor:
Selvam Thavaraj, Celia Murciano, Robert T. Wheeler, Linda S. Archambault, Remi L. Gratacap, Sarah L. Gaffen, Spyridoula Angeliki Nikou, Christian P. Zwirner, Rhonda Henley-Smith, Jonathan P. Richardson, David L. Moyes, Xuexin Yang, Nicole O. Ponde, Nessim Kichik, Andrew Donkin, Bernhard Hube, J. Ho, Christopher J. Tynan, Julian R. Naglik
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Ho, J, Yang, X, Nikou, S-A, Kichik, N, Donkin, A, Pond, N O, Richardson, J P, Gratacap, R, Archambault, L S, Zwirner, C P, Murciano, C, Henley-Smith, R, Thavaraj, S, Tynan, C J, Gaffen, S L, Hube, B, Wheeler, R T, Moyes, D L & Naglik, J R 2019, ' Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor ', Nature Communications . https://doi.org/10.1038/s41467-019-09915-2
Ho, J, Yang, X, Nikou, S A, Kichik, N, Donkin, A, Ponde, N O, Richardson, J P, L. Gratacap, R, S. Archambault, L, P. Zwirner, C, Murciano, C, Henley-Smith, R, Thavaraj, S, J. Tynan, C, L. Gaffen, S, Hube, B, T. Wheeler, R, Moyes, D L & Naglik, J R 2019, ' Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor ', Nature Communications, vol. 10, no. 1, 2297 . https://doi.org/10.1038/s41467-019-09915-2
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Ho, J, Yang, X, Nikou, S-A, Kichik, N, Donkin, A, Pond, N O, Richardson, J P, Gratacap, R, Archambault, L S, Zwirner, C P, Murciano, C, Henley-Smith, R, Thavaraj, S, Tynan, C J, Gaffen, S L, Hube, B, Wheeler, R T, Moyes, D L & Naglik, J R 2019, ' Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor ', Nature Communications . https://doi.org/10.1038/s41467-019-09915-2
Ho, J, Yang, X, Nikou, S A, Kichik, N, Donkin, A, Ponde, N O, Richardson, J P, L. Gratacap, R, S. Archambault, L, P. Zwirner, C, Murciano, C, Henley-Smith, R, Thavaraj, S, J. Tynan, C, L. Gaffen, S, Hube, B, T. Wheeler, R, Moyes, D L & Naglik, J R 2019, ' Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor ', Nature Communications, vol. 10, no. 1, 2297 . https://doi.org/10.1038/s41467-019-09915-2
Candida albicans is a fungal pathobiont, able to cause epithelial cell damage and immune activation. These functions have been attributed to its secreted toxin, candidalysin, though the molecular mechanisms are poorly understood. Here, we identify ep