Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Celia M. Longhurst"'
Publikováno v:
Experimental Cell Research. 314:1811-1822
Tetraspanin CD9 regulates cell motility and other adhesive processes in a variety of tissue types. Using transfected Chinese Hamster Ovary cells as our model system, we examined the cellular pathways critical for CD9 promoted cell migration. alpha 5
Autor:
Shila Cholera, Svetozar Grgurevich, Joseph T. Crossno, George A. Cook, Lisa K. Jennings, Celia M. Longhurst
Publikováno v:
Blood. 100:4502-4511
CD9, a 24-kDa member of the tetraspanin family, influences cellular growth and development, activation, adhesion, and motility. Our investigation focuses on the hypothesis that the CD9 second extracellular loop (EC2) is important in modulating cell a
Autor:
Joseph T. Crossno, Rajendra Raghow, Jianxong Bao, Celia M. Longhurst, Deborah A. Fitzgerald, Lisa K. Jennings, Thomas J. Fitzgerald, Melanie M. White, Jonathan D. Jacobs
Publikováno v:
Journal of Biological Chemistry. 277:32445-32452
CD9, a member of the tetraspanin family of proteins, is characterized by four transmembrane domains and two extracellular loops. Surface expression of CD9 on Chinese hamster ovary (CHO) cells dramatically enhances spreading and motility on fibronecti
Autor:
Ramin Homayouni, Lisa K. Jennings, Celia M. Longhurst, Benjamin Baker, Jayaprakash Kotha, Michael J. Herr, Henry E. Speich
Publikováno v:
Biochemical and biophysical research communications. 447(4)
Non-Hodgkin Lymphoma (NHL) is a type of hematological malignancy that affects two percent of the overall population in the United States. Tetraspanin CD9 is a cell surface protein that has been thoroughly demonstrated to be a molecular facilitator of
Publikováno v:
European Journal of Biochemistry. 263:104-110
A noncovalently associated complex comprising of CD9, the fibrinogen (Fg) receptor alphaIIbbeta3, integrin-associated protein (IAP), and glycoprotein (GP) Ib/V/IX complex was isolated from Chaps-solubilized human platelets. The CD9 complex was immuno
Autor:
Celia M. Longhurst, Lisa K. Jennings
Publikováno v:
Cellular and Molecular Life Sciences (CMLS). 54:514-526
Integrins, expressed on virtually every cell type, are proteins that mediated cellular interactions with components of the extracellular matrix (ECM) and cell surface integral plasma membrane proteins. In addition, integrins interact with the cytoske
Autor:
Jonathan D. Jacobs, Yi Lu, Chunxiang Zhang, Lisa K. Jennings, Celia M. Longhurst, Jayaprakash Kotha, Yunhui Cheng
Publikováno v:
Atherosclerosis. 203(2)
Vascular smooth muscle cell (VSMC) migration and proliferation are critical events in the development of neointima following vascular injury. In this study, we found that CD9 is constitutively expressed in the VSMC of the neointima of injured carotid
Autor:
Joseph A. Jakubowski, Willie Teng, Robert M. Scarborough, Anne Randolph, David R. Phillips, Lisa Nannizzi-Alaimo, Ann E. Arfsten, Lisa K. Jennings, Melanie M. White, Sanford J. Shattil, Celia M. Longhurst
Publikováno v:
Circulation. 96(5)
Background Integrilin (eptifibatide), a potent inhibitor of the fibrinogen binding function of GP IIb-IIIa, has been shown to reduce the thrombotic complications of angioplasty and of acute coronary syndromes. The present study was designed to determ