Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Celia J. Fang"'
Autor:
Eric J. Huang, Lindsey A. Criswell, Boris Reizis, Gianna E. Hammer, Barbara A. Malynn, Averil Ma, Mary C. Nakamura, Shigeru Oshima, Emre E. Turer, Celia J. Fang, Julio Barrera, Rommel Advincula, Kimberly E. Taylor, Baidong Hou, Anthony L. DeFranco
Publikováno v:
Nature Immunology. 12:1184-1193
Dendritic cells (DCs), which are known to support immune activation during infection, may also regulate immune homeostasis in resting animals. Here we show that mice lacking the ubiquitin-editing molecule A20 specifically in DCs spontaneously showed
Publikováno v:
Vaccine. 26:I22-I27
Nearly half of the proteins in the complement system serve in regulation. Control at the central step of C3 activation is provided by an orchestrated interplay of membrane and plasma regulators. A model system employing Chinese hamster ovary (CHO) ce
Autor:
John P. Atkinson, Timothy H.J. Goodship, Marina Noris, Véronique Frémeaux-Bacchi, Gaia Pianetti, M. Kathryn Liszewski, Celia J. Fang
Publikováno v:
Blood. 111:624-632
The hemolytic uremic syndrome (HUS) is a triad of microangiopathic hemolytic anemia, thrombocytopenia, and renal impairment. Genetic studies demonstrate that heterozygous mutations of membrane cofactor protein (MCP;CD46) predispose to atypical HUS (a
Autor:
Elizabeth A. Moulton, David J. Kavanagh, Timothy H.J. Goodship, Marina Noris, Véronique Frémeaux-Bacchi, Celia J. Fang, John P. Atkinson, M. Kathryn Liszewski, Anna Richards, Giuseppe Remuzzi
Publikováno v:
Molecular Immunology. 44:111-122
The hemolytic uremic syndrome is characterized by the triad of microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure. There are two general types. One occurs in epidemic form and is diarrheal associated (D+HUS). It has a good pr
Publikováno v:
Current Rheumatology Reviews. 2:233-244
Systemic lupus erythematosus (SLE) is a complex disease involving many different immune mechanisms, whose pathogenesis is not fully understood. In the past therapeutic interventions have employed medications with multiple immunological targets, makin
Publikováno v:
Autoimmunity Reviews. 4:515-519
Production of autoantibodies by B cells in systemic lupus erythematosus (SLE) can be interrupted via induction of regulatory and suppressor T cells. We have used the strategy of tolerizing lupus-prone (NZBxNZW)F(1) mice with an artificial peptide bas
Publikováno v:
Biochemistry. 36:307-316
T4 lysozyme and mutants thereof crystallize in different conformations that are related to each other by a bend about a hinge in the molecule. This observation suggests that the wild type protein may undergo a hinge-bending motion in solution to allo
Autor:
Li Li, Frank M. Torti, James C. Ryan, Hisashi Arase, William E. Seaman, Celia J. Fang, Suzy V. Torti, Eréne C. Niemi, Mary C. Nakamura, José A. Lebrón, Pamela J. Bjorkman
Ferritin is a spherical molecule composed of 24 subunits of two types, ferritin H chain (FHC) and ferritin L chain (FLC). Ferritin stores iron within cells, but it also circulates and binds specifically and saturably to a variety of cell types. For m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf4ecc291957097d8e45c7a5ccef6a61
https://resolver.caltech.edu/CaltechAUTHORS:20100405-110249328
https://resolver.caltech.edu/CaltechAUTHORS:20100405-110249328
Autor:
Marilyn K. Leung, John P. Atkinson, Celia J. Fang, Richard E. Hauhart, Paula Bertram, M. Kathryn Liszewski
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 183(5)
Although smallpox was eradicated as a global illness more than 30 years ago, variola virus and other related pathogenic poxviruses, such as monkeypox, remain potential bioterrorist weapons or could re-emerge as natural infections. Poxviruses express
Publikováno v:
British journal of haematology. 143(3)
Both atypical haemolytic uraemic syndrome (aHUS) and the HELLP syndrome (haemolytic anaemia, elevated liver enzymes, and low platelets) are thrombotic microangiopathies characterized by microvascular endothelial activation, cell injury and thrombosis