Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Celia Goeldner"'
Autor:
Celia Goeldner, Priya S. Kishnani, Brian G. Skotko, Julian Lirio Casero, Joerg F. Hipp, Michael Derks, Maria-Clemencia Hernandez, Omar Khwaja, Sian Lennon-Chrimes, Jana Noeldeke, Sabine Pellicer, Lisa Squassante, Jeannie Visootsak, Christoph Wandel, Paulo Fontoura, Xavier Liogier d’Ardhuy, Clematis Study Group
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 14, Iss 1, Pp 1-14 (2022)
Abstract Background There are currently no pharmacological therapies to address the intellectual disability associated with Down syndrome. Excitatory/inhibitory imbalance has been hypothesized to contribute to impairments in cognitive functioning in
Externí odkaz:
https://doaj.org/article/82719940df4e43d5917b4ba65a910b48
Autor:
Celia, Goeldner, Priya S, Kishnani, Brian G, Skotko, Julian Lirio, Casero, Joerg F, Hipp, Michael, Derks, Maria-Clemencia, Hernandez, Omar, Khwaja, Sian, Lennon-Chrimes, Jana, Noeldeke, Sabine, Pellicer, Lisa, Squassante, Jeannie, Visootsak, Christoph, Wandel, Paulo, Fontoura, Xavier Liogier, d'Ardhuy, Alessandro, Zuddas
Publikováno v:
Journal of neurodevelopmental disorders. 14(1)
There are currently no pharmacological therapies to address the intellectual disability associated with Down syndrome. Excitatory/inhibitory imbalance has been hypothesized to contribute to impairments in cognitive functioning in Down syndrome. Negat
Autor:
Jana Noeldeke, Jamie O. Edgin, James H. Heller, Celia Goeldner, Omar Khwaja, Xavier Liogier d'Ardhuy, Jeannie Visootsak, Sarah J. Hart, Lisa Squassante, Priya S. Kishnani, Gail A. Spiridigliozzi
Publikováno v:
American journal of medical genetics. Part A. 179(1)
Measures of adaptive behavior are important in the assessment and treatment of individuals with intellectual disabilities (ID). The purpose of the current study was to evaluate the stability of an established and a novel measure of adaptive behavior
Autor:
Silvia Gatti, Theresa M. Ballard, Frédéric Knoflach, Daniel Umbricht, Juergen Wichmann, Celia Goeldner
Publikováno v:
Neuropharmacology. 64
Cognitive impairment, in particular of attention and memory, is often reported by patients suffering from major depressive disorder (MDD) and deficits in attention are part of the current diagnostic criteria of MDD. Objectively measured cognitive def
Publikováno v:
Psychopharmacology. 222(2)
Ro 64-6198, the prototypical non-peptide nociceptin/orphanin FQ peptide (NOP) receptor agonist, has potent anxiolytic-like effects in several preclinical models and species. However the effects of Ro 64-6198 on distinctive anxiety-provoking condition
Autor:
Theresa M. Ballard, Susanne Ostrowitzki, Stefanie Saenger, Will Spooren, Celia Goeldner, Johann Rudolf Frey, Eric Prinssen, Friedrich Metzger, Edilio Borroni, Laurence Ozmen
Publikováno v:
Growth hormoneIGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. 21(5)
Objective Due to its potent neurotrophic activity, insulin-like growth factor I (IGF-I) has been proposed many times for therapeutic application in disorders of the central nervous system (CNS). However, insufficient brain delivery to yield beneficia
Autor:
Pierre-Eric Lutz, Abdel-Mouttalib Ouagazzal, Celia Goeldner, Thomas Halter, Daniel Clesse, Emmanuel Darcq, Brigitte L. Kieffer
Publikováno v:
Biological Psychiatry
Biological Psychiatry, Elsevier, 2011, 69 (3), pp.236-244. ⟨10.1016/j.biopsych.2010.08.021⟩
Biological Psychiatry, Elsevier, 2011, 69 (3), pp.236-244. ⟨10.1016/j.biopsych.2010.08.021⟩
Background Opiate abuse is a chronic relapsing disorder, and maintaining prolonged abstinence remains a major challenge. Protracted abstinence is characterized by lowered mood, and clinical studies show elevated comorbidity between addiction and depr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4777c3640342eb738779af7aa1d4af61
https://hal.archives-ouvertes.fr/hal-02437996/document
https://hal.archives-ouvertes.fr/hal-02437996/document
Publikováno v:
European Neuropsychopharmacology
European Neuropsychopharmacology, Elsevier, 2011, 21 (11), pp.835-840. ⟨10.1016/j.euroneuro.2011.02.002⟩
European Neuropsychopharmacology, Elsevier, 2011, 21 (11), pp.835-840. ⟨10.1016/j.euroneuro.2011.02.002⟩
International audience; Addiction is a brain chronic relapsing disorder associated with emotional distress. The serotonergic system and especially the 5-HT 1A receptor crucially regulate emotional behaviors both in humans and rodents. Using [ 35 S]GT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d02e2ef285f1c9022e1fd67934b48041
https://hal.archives-ouvertes.fr/hal-02437993/file/Lutz-ENPP_nihms-277486.pdf
https://hal.archives-ouvertes.fr/hal-02437993/file/Lutz-ENPP_nihms-277486.pdf
Publikováno v:
Hippocampus.
Nociceptin/orphanin-FQ (N/OFQ) peptide and its receptor (NOP: N/OFQ opioid peptide receptor) are highly expressed in the hippocampus, but their functional role remains poorly understood. We recently showed that hippocampal N/OFQ inhibits learning and
Publikováno v:
Neurobiology of Learning and Memory
Neurobiology of Learning and Memory, Elsevier, 2009, 91 (4), pp.393-401. ⟨10.1016/j.nlm.2008.12.001⟩
Neurobiology of Learning and Memory, 2009, 91 (4), pp.393-401. ⟨10.1016/j.nlm.2008.12.001⟩
Neurobiology of Learning and Memory, Elsevier, 2009, 91 (4), pp.393-401. ⟨10.1016/j.nlm.2008.12.001⟩
Neurobiology of Learning and Memory, 2009, 91 (4), pp.393-401. ⟨10.1016/j.nlm.2008.12.001⟩
International audience; The present study investigated whether the selective nociceptin opioid peptide (NOP) receptor agonist, Ro64-6198, impairs acquisition of fear conditioning through glutamatergic mechanisms. Systemic administration of Ro64-6198
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74866423900fa424f03c70b2ddd30fb3
https://www.hal.inserm.fr/inserm-00384248
https://www.hal.inserm.fr/inserm-00384248