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pro vyhledávání: '"Celia Gazdar"'
Autor:
Celia Gazdar, Ingrid Svenson, Yeong-Jae Seok, Nalini Yadla, Alan Peterkofsky, Byeong Ryong Lee
Publikováno v:
Biochemistry. 35:236-242
The gene encoding enzyme I of the phosphoenolpyruvate:sugar phosphotransferase system from an Escherichia coli enzyme I mutant was cloned and sequenced. The mutation was shown to be a guanine to adenine transition resulting in an altered protein in w
Autor:
Alan Peterkofsky, Celia Gazdar
Publikováno v:
Proceedings of the National Academy of Sciences. 76:1099-1103
Sugars such as glucose are transported into Escherichia coli by a coupled phosphorylation mechanism (the phosphoenolpyruvate:sugar phosphotransferase system, PTS). Transport of sugars through the PTS results in inhibition of adenylate cyclase [ATP py
Autor:
Alan Peterkofsky, Celia Gazdar
Publikováno v:
Bioscience Reports. 1:53-60
When a wild-type strain of Escherichia coli contains lactose permease, the accumulation of cyclic AMP (cAMP) by intact cells is inhibited by lactose. This inhibitory effect of lactose is observed in a strain with a mutant cAMP phosphodiesterase and t
Publikováno v:
Archives of Biochemistry and Biophysics. 188:47-55
The activity of adenylate cyclase of Escherichia coli measured in toluene-treated cells under standard conditions is subject to control by the phosphoenolpyruvate:sugar phosphotransferase system (PTS). Sugars such as glucose, which are transported by
Autor:
Celia Gazdar, Alan Peterkofsky
Publikováno v:
Journal of Supramolecular Structure. 9:219-230
A model for the regulation of the activity of Escherichia coli adenylate cyclase is presented. It is proposed that Enzyme I of the phosphoenolpyruvate:sugar phosphotransferase system (PTS) interacts in a regulatory sense with the catalytic unit of ad
Publikováno v:
Archives of Biochemistry and Biophysics. 223:503-513
Under certain growth conditions, some strains of Escherichia coli accumulate toxic levels of methylglyoxal. This report characterizes a strain which synthesizes a mutant cAMP receptor protein in an adenylate cyclase deletion background. When cultured
Measurements of Rates of Adenosine 3′:5′-Cyclic Monophosphate Synthesis in Intact Escherichia coli B
Autor:
Alan Peterkofsky, Celia Gazdar
Publikováno v:
Proceedings of the National Academy of Sciences. 70:2149-2152
A method for labeling adenosine 3′:5′-cyclic monophosphate in vivo from precursor adenosine followed by quantitative analysis of the labeled nucleotide is described. When the labeling period is short and the specific activity of the ATP pool is d
Autor:
Alan Peterkofsky, Celia Gazdar
Previous studies in E. coli B have demonstrated an inverse correlation between the presence of glucose in the medium and the accumulation of cyclic AMP in the medium. This observation could not be explained by the action of glucose as a repressor of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06212cd0bfae71b00319975618a60455
https://europepmc.org/articles/PMC388445/
https://europepmc.org/articles/PMC388445/
Autor:
Celia Gazdar, Alan Peterkofsky
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 68(11)
Measurements of adenosine 3′:5′-cyclic monophosphate (cAMP) concentrations have been made in Escherichia coli under various conditions. Different strains of E. coli accumulate different extracellular concentrations of cAMP (0.2-4 μm) at stationa