Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Celia Fontanillo"'
Autor:
Rachid Safi, Suzanne E. Wardell, Paige Watkinson, Xiaodi Qin, Marissa Lee, Sunghee Park, Taylor Krebs, Emma L. Dolan, Adam Blattler, Toshiya Tsuji, Surendra Nayak, Marwa Khater, Celia Fontanillo, Madeline A. Newlin, Megan L. Kirkland, Yingtian Xie, Henry Long, Emma C. Fink, Sean W. Fanning, Scott Runyon, Myles Brown, Shuichan Xu, Kouros Owzar, John D. Norris, Donald P. McDonnell
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Most prostate cancers express the androgen receptor (AR), and tumor growth and progression are facilitated by exceptionally low levels of systemic or intratumorally produced androgens. Thus, absolute inhibition of the androgen signaling axis
Externí odkaz:
https://doaj.org/article/46ae3691cddb47bb9982590cd3da970d
Autor:
Mónica del Rey, Rocío Benito, Celia Fontanillo, Francisco J Campos-Laborie, Kamila Janusz, Talía Velasco-Hernández, María Abáigar, María Hernández, Rebeca Cuello, Daniel Borrego, Dionisio Martín-Zanca, Javier De Las Rivas, Ken I Mills, Jesús M Hernández-Rivas
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126555 (2015)
The presence of SF3B1 gene mutations is a hallmark of refractory anemia with ring sideroblasts (RARS). However, the mechanisms responsible for iron accumulation that characterize the Myelodysplastic Syndrome with ring sideroblasts (MDS-RS) are not co
Externí odkaz:
https://doaj.org/article/9a4f80a8c7044e87a92f0534d3c0e4bb
Autor:
María González-González, Luís Muñoz-Bellvis, Carlos Mackintosh, Celia Fontanillo, M Laura Gutiérrez, M Mar Abad, Oscar Bengoechea, Cristina Teodosio, Emilio Fonseca, Manuel Fuentes, Javier De Las Rivas, Alberto Orfao, José María Sayagués
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42683 (2012)
BACKGROUND: Most sporadic colorectal cancer (sCRC) deaths are caused by metastatic dissemination of the primary tumor. New advances in genetic profiling of sCRC suggest that the primary tumor may contain a cell population with metastatic potential. H
Externí odkaz:
https://doaj.org/article/c3875bdb5dd04007893868c82f1ab0cb
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24289 (2011)
Functional analysis of large sets of genes and proteins is becoming more and more necessary with the increase of experimental biomolecular data at omic-scale. Enrichment analysis is by far the most popular available methodology to derive functional i
Externí odkaz:
https://doaj.org/article/c35bf68e0e3e438bbff83c5f9c6d7345
Autor:
José María Sayagués, Celia Fontanillo, María del Mar Abad, María González-González, María Eugenia Sarasquete, Maria del Carmen Chillon, Eva Garcia, Oscar Bengoechea, Emilio Fonseca, Marcos Gonzalez-Diaz, Javier De las Rivas, Luís Muñoz-Bellvis, Alberto Orfao
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13752 (2010)
BackgroundFor years, the genetics of metastatic colorectal cancer (CRC) have been studied using a variety of techniques. However, most of the approaches employed so far have a relatively limited resolution which hampers detailed characterization of t
Externí odkaz:
https://doaj.org/article/da8d45718f6f40cc9e7b631a4ee4abe8
Autor:
Javier De Las Rivas, Celia Fontanillo
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 6, p e1000807 (2010)
Externí odkaz:
https://doaj.org/article/8eaa0dc8a2b44b9a9d1378f8feca206c
Autor:
José Ángel Hernández, Ana Eugenia Rodríguez, Marcos González, Rocío Benito, Celia Fontanillo, Virgilio Sandoval, Mercedes Romero, Guillermo Martín-Núñez, Alfonso García de Coca, Rosa Fisac, Josefina Galende, Isabel Recio, Francisco Ortuño, Juan Luis García, Javier de las Rivas, Norma Carmen Gutiérrez, Jesús F. San Miguel, Jesús María Hernández
Publikováno v:
Haematologica, Vol 94, Iss 3 (2009)
Background Among patients with B-cell chronic lymphoid leukemia, those with 13q14 deletion have a favorable outcome. However, whether the percentage of cells with 13q- influences the prognosis or the biological characteristics of this disease is unkn
Externí odkaz:
https://doaj.org/article/c047355b29f14df8a2d302f814a0e0f6
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e3911 (2008)
BackgroundAnalysis of gene expression data using genome-wide microarrays is a technique often used in genomic studies to find coexpression patterns and locate groups of co-transcribed genes. However, most studies done at global "omic" scale are not f
Externí odkaz:
https://doaj.org/article/3dc48efc3b004747b78ec7bbd1c7da40
Akademický článek
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Autor:
Joshua Hansen, John E. Dick, Philip P Chamberlain, Emily Rychak, Gang Lu, In Sock Jang, Jean C.Y. Wang, Thomas Clayton, Celia Fontanillo, Derek Mendy, Michael Pourdehnad, Jinhong Fan, Stanley W.K. Ng, Eileen Tran, Mark Rolfe, Nathan Mbong, Kai Wang, Chin-Chun Lu, James Carmichael, Christine Surka, Mary E Matyskiela, Daniel W. Pierce, Mark D. Minden, Liqing Jin, Antonia Lopez-Girona, Brian E. Cathers, Elizabeth Anne Tindall, Adrian Contreras, Christy Hsu
Publikováno v:
Blood. 137:661-677
A number of clinically validated drugs have been developed by repurposing the CUL4-DDB1-CRBN-RBX1 (CRL4CRBN) E3 ubiquitin ligase complex with molecular glue degraders to eliminate disease-driving proteins. Here, we present the identification of a fir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390854bdb0e3f67bbd5f3627b5b5ffe5
https://doi.org/10.1182/blood.2020008676
https://doi.org/10.1182/blood.2020008676