Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Celia A. Kanashiro"'
Autor:
Sandra Claro, Alice T. Ferreira, Raouf A. Khalil, Maria Etsuko Miyamoto Oshiro, Celia A. Kanashiro
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 322:964-972
The use of gamma-radiation in treatment of pelvic cancer is associated with injury of healthy surrounding tissues and disorders of intestinal motility; however, the cellular mechanisms involved are unclear. We tested the hypothesis that exposure of v
Autor:
Gabor Halmos, Andrew V. Schally, Celia A. Kanashiro, Attila Nagy, Anton Stangelberger, Karoly Szepeshazi
Publikováno v:
The Prostate. 66:200-210
BACKGROUND Receptors for luteinizing hormone-releasing hormone (LHRH) on human prostate cancers can be used for targeted chemotherapy with cytotoxic analogs of LHRH, such as AN-207, which consists of superactive doxorubicin derivative 2-pyrrolino dox
Autor:
Celia A. Kanashiro, Frank Köster, Gabor L. Toller, Judit Horvath, Marta Zarandi, Kevin L. Kovitz, Karoly Szepeshazi, Kate Groot, Jozsef L. Varga, Gabor Halmos, Alexandre Havt, Andrew V. Schally
Publikováno v:
Proceedings of the National Academy of Sciences. 102:17424-17429
Various attempts to detect human pituitary growth hormone-releasing hormone receptor (pGHRH-R) in neoplastic extrapituitary tissues have thus far failed. Recently, four splice variants (SVs) of GHRH-R have been described, of which SV1 has the highest
Autor:
Anton Stangelberger, Patricia Armatis, Brian D. Hammann, Ren Zhi Cai, Andrew V. Schally, Benjamin Baker, Celia A. Kanashiro, Jozsef L. Varga, Marta Zarandi
Publikováno v:
European Journal of Cancer. 41:2735-2744
Bombesin/gastrin-releasing peptide (BN/GRP) antagonists RC-3940-II and RC-3940-Et, and growth hormone-releasing hormone (GHRH) antagonists MZ-J-7-118 and RC-J-29-18 inhibit the growth of human androgen-independent PC-3 and DU-145 prostate cancers in
Publikováno v:
International Journal of Cancer. 112:570-576
We investigated the effects of antagonists of growth hormone-releasing hormone (GHRH) alone and in combination with bombesin/gastrin-releasing peptide (BN/GRP) antagonist RC-3940-II on the growth of H-69 human small cell lung carcinoma (SCLC) xenogra
Autor:
Celia A. Kanashiro, Raouf A. Khalil
Publikováno v:
American Journal of Physiology-Cell Physiology. 280:C34-C45
Gender differences in vascular reactivity have been suggested; however, the cellular mechanisms involved are unclear. We tested the hypothesis that the gender differences in vascular reactivity reflect gender-related, possibly estrogen-mediated, dist
Publikováno v:
Journal of Cardiovascular Pharmacology. 35:491-501
The cellular mechanisms of coronary vasospasm are unclear, and a role for protein kinase C (PKC) activation by the endogenous vasoconstrictors endothelin-1 (ET-1) and prostaglandin F2alpha (PGF2alpha) has been suggested. In this study, we developed a
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 278:R295-R303
Vascular reactivity has been shown to be reduced during pregnancy and to be enhanced during chronic inhibition of nitric oxide (NO) synthesis in pregnant rats; however, the cellular mechanisms involved are unclear. The purpose of this study was to in
Autor:
Celia A Kanashiro, Raouf A Khalil
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 76:1110-1119
Vasoactive eicosanoids have been implicated in the pathogenesis of coronary vasospasms. The signaling mechanisms of eicosanoid-induced coronary vasoconstriction are unclear, and a role for protein kinase C (PKC) has been suggested. Activated PKC unde
Autor:
Gabor Halmos, Benjamin Baker, Florian Hohla, Elmar Aigner, Chandrika B. Kannadka, Andrew V. Schally, Christian Datz, Angelika Moder, Celia A. Kanashiro, Stefan Buchholz
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 104(47)
Bombesin (BN) or gastrin-releasing peptide (GRP) can stimulate the growth of neoplasms such as breast cancer and small-cell lung carcinoma (SCLC). Antagonists of BN/GRP have been shown to inhibit these cancers. We evaluated whether antagonists of BN/