Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Celia A Williams"'
Publikováno v:
Journal of Intellectual Disability Research. 32:479-484
People with Down's syndrome (DS) are at high risk of developing Alzheimer's disease (AD). The gene coding for superoxide dismutase-/ on chromosome 21 resulting in excess activity of the enzyme with consequent risk of oxidative damage might account fo
Autor:
P.E. Sylvester, Helen Quinn, Celia A. Williams, J. W. T. Dickerson, Elaine C. Wright, Paula J. H. Gosling
Publikováno v:
Journal of Intellectual Disability Research. 29:173-177
A standard xylose absorption test was carried out in 14 people with Down's syndrome (DS) and in 14 age-matched mentally deficient controls; a further 30 people with DS were similarly investigated. Mentally deficient people as a group were found to ha
Autor:
Celia K. Williams, Miles D. Koppang
Publikováno v:
Electroanalysis. 18:2121-2127
In a mixture of primary and secondary aliphatic amines, the primary amines were derivatized (masked) with o-phthalaldehyde (OPA) followed by derivatization of the remaining secondary amines with ferrocenecarboxylic acid chloride (FAC). The “tagged
Publikováno v:
Langmuir. 20:4220-4225
The binding behavior of sodium cholate, a trihydroxy hydrophobic bile salt, by a polyacrylamide resin with N,N,N-trimethylammonium dodecyl chloride (QPDA12) pendant group was determined with varying buffer conditions and in the presence of 1,2-propan
Publikováno v:
Canadian Journal of Chemistry. 81:133-140
The binding of sodium chenodeoxycholate, a hydrophobic bile salt, by a polyacrylamide resin with N,N,N-trimethylammonium dodecyl chloride (QPDA12) pendant groups was studied in the presence of elevated concentrations of competing anions. The equilibr
Publikováno v:
Canadian Journal of Chemistry. 80:89-93
The binding of a hydrophobic bile salt, sodium chenodeoxycholate, by a polyacrylamide with N,N,N-trimethylammonium dodecyl chloride (QPDA12) pendant groups was studied to evaluate the thermodynamic parameters associated with the binding. The Langmuir
Publikováno v:
General Pharmacology: The Vascular System. 34:183-191
Acute S 22068 (24 mg/kg po) improved glucose tolerance and increased insulin sensitivity, assessed as the acute blood glucose response to exogenous insulin. The same acute dose did not stimulate insulin secretion or induce hypoglycemia in fed animals
Publikováno v:
British Journal of Pharmacology. 128:1586-1592
Acute SR 58611A (0.25 mg kg−1), was effective in reducing the blood glucose response to a glucose tolerance test (GTT) in normal lean (control) and spontaneously obese/diabetic CBA/Ca mice and to be equipotent to 1.25 mg kg−1 glibenclamide in lea