Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Celestine N. Chi"'
Autor:
Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract The virus life cycle depends on host-virus protein-protein interactions, which often involve a disordered protein region binding to a folded protein domain. Here, we used proteomic peptide phage display (ProP-PD) to identify peptides from th
Externí odkaz:
https://doaj.org/article/0dc8318509ba40b4a7a4978a68d342a6
Autor:
Dzmitry Ashkinadze, Harindranath Kadavath, Aditya Pokharna, Celestine N. Chi, Michael Friedmann, Dean Strotz, Pratibha Kumari, Martina Minges, Riccardo Cadalbert, Stefan Königl, Peter Güntert, Beat Vögeli, Roland Riek
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
In this manuscript the authors report accurate multi-state protein structures of the PDZ domain using biological NMR. By looking into protein structural states, the authors report an allosteric pathway at atomic resolution that validates previously r
Externí odkaz:
https://doaj.org/article/6b3bc663eccc4bfea2bb66b7062c25de
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
Reconstruction of an ancient nuclear coactivator binding domain (NCBD) of CREB-binding protein from a bilaterian animal ancestor living 600 million years ago reveals conserved dynamic properties in human NCBD.
Externí odkaz:
https://doaj.org/article/b3678dcf1c654474a6663ba47b10204e
Autor:
Sabeen Survery, Fredrik Hurtig, Syed Razaul Haq, Jens Eriksson, Lionel Guy, K. Johan Rosengren, Ann-Christin Lindås, Celestine N. Chi
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Chi and coworkers characterise proteins of Heimdallarchaeeota LC3, a member of the Asgard super phylum, and specifically investigate heim-Profilin and heim-Actin, and their interactions with polyproline and phospholipids. They also determine the 3D-s
Externí odkaz:
https://doaj.org/article/748467ba73d04fdf9e54fc72819537ab
Publikováno v:
ACS Omega, Vol 6, Iss 38, Pp 24377-24381 (2021)
Externí odkaz:
https://doaj.org/article/a5057f9cb16442efbab862e2f401fdc4
Autor:
Mohammed Mouhib, Celestine N. Chi
Publikováno v:
MicrobiologyOpen, Vol 11, Iss 3, Pp n/a-n/a (2022)
Abstract Gaining structural information on membrane proteins in their native lipid environment is a long‐standing challenge in molecular biology. Instead, it is common to employ membrane mimetics, which has been shown to affect protein structure, d
Externí odkaz:
https://doaj.org/article/dfb829bb767d4b5e97ea52bb417a23c6
Autor:
Parker J. Nichols, Alexandra Born, Morkos A. Henen, Dean Strotz, Julien Orts, Simon Olsson, Peter Güntert, Celestine N. Chi, Beat Vögeli
Publikováno v:
Molecules, Vol 22, Iss 7, p 1176 (2017)
Although often depicted as rigid structures, proteins are highly dynamic systems, whose motions are essential to their functions. Despite this, it is difficult to investigate protein dynamics due to the rapid timescale at which they sample their conf
Externí odkaz:
https://doaj.org/article/c5fea171868541559c5e42bcd17e37ab
Autor:
Maurice Michel, Carlos Benítez-Buelga, Patricia A. Calvo, Bishoy M. F. Hanna, Oliver Mortusewicz, Geoffrey Masuyer, Jonathan Davies, Olov Wallner, Kumar Sanjiv, Julian J. Albers, Sergio Castañeda-Zegarra, Ann-Sofie Jemth, Torkild Visnes, Ana Sastre-Perona, Akhilesh N. Danda, Evert J. Homan, Karthick Marimuthu, Zhao Zhenjun, Celestine N. Chi, Antonio Sarno, Elisée Wiita, Catharina von Nicolai, Anna J. Komor, Varshni Rajagopal, Sarah Müller, Emily C. Hank, Marek Varga, Emma R. Scaletti, Monica Pandey, Stella Karsten, Hanne Haslene-Hox, Simon Loevenich, Petra Marttila, Azita Rasti, Kirill Mamonov, Florian Ortis, Fritz Schömberg, Olga Loseva, Josephine Stewart, Nicholas D’Arcy-Evans, Tobias Koolmeister, Martin Henriksson, Dana Michel, Ana de Ory, Lucia Acero, Oriol Calvete, Martin Scobie, Christian Hertweck, Ivan Vilotijevic, Christina Kalderén, Ana Osorio, Rosario Perona, Alexandra Stolz, Pål Stenmark, Ulrika Warpman Berglund, Miguel de Vega, Thomas Helleday
Publikováno v:
Science. 376:1471-1476
Oxidative DNA damage is recognized by 8-oxoguanine (8-oxoG) DNA glycosylase 1 (OGG1), which excises 8-oxoG, leaving a substrate for apurinic endonuclease 1 (APE1) and initiating repair. Here, we describe a small molecule (TH10785) that interacts with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3729c4fdd8e5f18775de3d2f9e81a847
https://doi.org/10.1126/science.abf8980
https://doi.org/10.1126/science.abf8980
Autor:
Filip Mihalic, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson
The infection and replication cycle of all viruses depend on interactions between viral and host proteins. Each of these protein-protein interactions is therefore a potential drug target. These host-virus interactions often involve a disordered prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9ea2a81b948ccf7e96474b1429ffcc2
https://doi.org/10.1101/2022.10.07.511324
https://doi.org/10.1101/2022.10.07.511324
Autor:
Greta Hultqvist, Emma Åberg, Carlo Camilloni, Gustav N Sundell, Eva Andersson, Jakob Dogan, Celestine N Chi, Michele Vendruscolo, Per Jemth
Publikováno v:
eLife, Vol 6 (2017)
Protein-protein interactions involving intrinsically disordered proteins are important for cellular function and common in all organisms. However, it is not clear how such interactions emerge and evolve on a molecular level. We performed phylogenetic
Externí odkaz:
https://doaj.org/article/4ec0392854ce45d69e6b992fc968cade