Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Celestial T, Yap"'
Publikováno v:
The Asia Pacific Scholar, Vol 8, Iss 4, Pp 50-52 (2023)
Externí odkaz:
https://doaj.org/article/0e20ba5496d8458e99459a010fe56c14
Publikováno v:
Biomedicines, Vol 8, Iss 9, p 316 (2020)
Signal transducer and activator of transcription (STAT) proteins, and in particular STAT3, have been established as heavily implicated in cancer. Recently, the involvement of STAT5 signalling in the pathology of cancer has been shown to be of increas
Externí odkaz:
https://doaj.org/article/09a382540a554063a658c8d6e73da7b4
Autor:
Zhi-Qiang Ling, Peishi Chen, Lian-Lian Hong, Xuan-Yu Hu, Celestial T. Yap, Qi Hao, Han-Ming Shen, Yi Ren, Mingzhu Tang, Boon-Huat Bay, Jiaqing Chen, Leng-Kuan Cheong
Publikováno v:
Free Radical Biology and Medicine. 166:128-139
The liver kinase B1 (LKB1) is an important tumor suppressor and its loss-of-function mutations are observed in around 16% of non-small cell lung cancer (NSCLC) cases. One of the main functions of LKB1 is to activate AMP-activated protein kinase (AMPK
Autor:
Shima Tavakol, Milad Ashrafizadeh, Shuo Deng, Maryam Azarian, Asghar Abdoli, Mahsa Motavaf, Delaram Poormoghadam, Hashem Khanbabaei, Elham Ghasemipour Afshar, Ali Mandegary, Abbas Pardakhty, Celestial T. Yap, Reza Mohammadinejad, Alan Prem Kumar
Publikováno v:
Biomolecules, Vol 9, Iss 10, p 530 (2019)
Autophagy modulation is considered to be a promising programmed cell death mechanism to prevent and cure a great number of disorders and diseases. The crucial step in designing an effective therapeutic approach is to understand the correct and accura
Externí odkaz:
https://doaj.org/article/76986cc5a4b64371a23ddf0d2c563790
Autor:
Peter E. Lobie, Tuan Zea Tan, Alan Prem Kumar, Soo-Chin Lee, Ching Wan Chan, Lingzhi Wang, Vijay Pandey, Celestial T. Yap, Ruby Yun-Ju Huang, Gautam Sethi, Boon Cher Goh, Xianning Lai, Hui Li Ang, Benjamin BoJun Huang, Yi Yuan
Publikováno v:
Theranostics
BReast tumor Kinase (BRK, also known as PTK6) is a non-receptor tyrosine kinase that is highly expressed in breast carcinomas while having low expression in the normal mammary gland, which hints at the oncogenic nature of this kinase in breast cancer
Autor:
Khay Guan Yeoh, Calvin Jianyi Koh, Lihan Zhou, Joanne Yoong, Chung King Chia, Ritika Kapoor, Sun Young Rha, Heng-Phon Too, Jaideepraj Rao, Feng Zhu, Hyun Cheol Chung, Asim Shabbir, Celestial T. Yap, Kong-Peng Lam, Yew Chung Tang, Wei Peng Yong, Patrick C.K. Goo, Ruiyang Zou, Jimmy Bok Yan So, Stephen Tsao, Jonathan Wei Jie Lee, Mikael Hartman
Publikováno v:
Gut
ObjectiveAn unmet need exists for a non-invasive biomarker assay to aid gastric cancer diagnosis. We aimed to develop a serum microRNA (miRNA) panel for identifying patients with all stages of gastric cancer from a high-risk population.DesignWe condu
Publikováno v:
ProteomicsREFERENCES. 22(9)
Protein O-GlcNAcylation is a specific form of protein glycosylation that targets a wide range of proteins with important functions. O-GlcNAcylation is known to be deregulated in cancer and has been linked to multiple aspects of cancer pathology. Desp
Autor:
Anupam Bishayee, Gautam Sethi, Celestial T. Yap, Alan Prem Kumar, Shuo Deng, Muthu K. Shanmugam
Publikováno v:
Cancer. 125:1228-1246
Autophagy, also known as macroautophagy, is a tightly regulated process involved in the stress responses, such as starvation. It is a vacuolar, lysosomal pathway for the degradation of damaged proteins and organelles in eukaryotic cells. Autophagy al
Autor:
Vennila Gopal, Arpita Datta, Alan Prem Kumar, Kenneth Chun-Hong Yap, Tuan Zea Tan, Shuo Deng, Shing Chuan Hooi, Mun Leng Lye, Mei Shan Ong, Celestial T. Yap, Gautam Sethi, Clarissa Esmeralda Halim
Publikováno v:
Cancers
Cancers, Vol 13, Iss 1882, p 1882 (2021)
Cancers, Vol 13, Iss 1882, p 1882 (2021)
Simple Summary The epithelial to mesenchymal transition (EMT) is a well-documented process in the study of cancer metastases. The cytoskeleton is an intricate network involved in various cellular activities and impacts cell shape, division, trafficki
Autor:
Shima Tavakol, Elham Ghasemipour Afshar, Delaram Poormoghadam, Maryam Azarian, Mahsa Motavaf, Alan Prem Kumar, Abbas Pardakhty, Ali Mandegary, Reza Mohammadinejad, Celestial T. Yap, Shuo Deng, Asghar Abdoli, Milad Ashrafizadeh, Hashem Khanbabaei
Publikováno v:
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Biomolecules, Vol 9, Iss 10, p 530 (2019)
Recercat. Dipósit de la Recerca de Catalunya
instname
Biomolecules
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Biomolecules, Vol 9, Iss 10, p 530 (2019)
Recercat. Dipósit de la Recerca de Catalunya
instname
Biomolecules
Funding: this work was supported by a grant from NMRC-CIRG to CTY. APK was supported by grants from National Medical Research Council of Singapore, NCIS Yong Siew Yoon Research Grant through donations from the Yong Loo Lin Trust and by the National R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54863b79b77e635135af63868b1092c7
http://hdl.handle.net/2072/440875
http://hdl.handle.net/2072/440875