Zobrazeno 1 - 10 of 570 pro vyhledávání: '"Celestia S Higano"'
1
Akademický článek
First-in-human, phase 1 study of PF-06753512, a vaccine-based immunotherapy regimen (VBIR), in non-metastatic hormone-sensitive biochemical recurrence and metastatic castration-resistant prostate cancer (mCRPC)
Autor: Tian Zhang, Nicholas J Vogelzang, Daniel P Petrylak, Ravi A Madan, Karen A Autio, Ray Li, Helen Cho, Szu-Yu Tang, Celestia S Higano, Luke Nordquist, Leonard J Appleman, Xin-Hua Zhu, Hani Babiker, Sandip M Prasad, Michael T Schweizer, Stephane Billotte, Nora Cavazos, Orlaith Bogg, Kam Chan, Megan Kaneda, I-Ming Wang, Jenny Zheng, Robert Hollingsworth, Kenneth A Kern
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 3 (2023)
Background This phase 1 study evaluated PF-06753512, a vaccine-based immunotherapy regimen (PrCa VBIR), in two clinical states of prostate cancer (PC), metastatic castration-resistant PC (mCRPC) and biochemical recurrence (BCR).Methods For dose escal
Externí odkaz: https://doaj.org/article/a4a8a3a078ab4567a1641ae4c2b5d1db
Zobrazit plný text záznamu
2
Akademický článek
Intermittent Androgen Suppression: Estimating Parameters for Individual Patients Based on Initial PSA Data in Response to Androgen Deprivation Therapy.
Autor: Yoshito Hirata, Kai Morino, Koichiro Akakura, Celestia S Higano, Nicholas Bruchovsky, Teresa Gambol, Susan Hall, Gouhei Tanaka, Kazuyuki Aihara
Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0130372 (2015)
When a physician decides on a treatment and its schedule for a specific patient, information gained from prior patients and experience in the past is taken into account. A more objective way to make such treatment decisions based on actual data would
Externí odkaz: https://doaj.org/article/f9dfd69edd1840d084bdf8a38549fa9d
Zobrazit plný text záznamu
3
Akademický článek
Prostate cancer characteristics associated with response to pre-receptor targeting of the androgen axis.
Autor: Elahe A Mostaghel, Andrew Morgan, Xiaotun Zhang, Brett T Marck, Jing Xia, Rachel Hunter-Merrill, Roman Gulati, Stephen Plymate, Robert L Vessella, Eva Corey, Celestia S Higano, Alvin M Matsumoto, R Bruce Montgomery, Peter S Nelson
Publikováno v: PLoS ONE, Vol 9, Iss 10, p e111545 (2014)
Factors influencing differential responses of prostate tumors to androgen receptor (AR) axis-directed therapeutics are poorly understood, and predictors of treatment efficacy are needed. We hypothesized that the efficacy of inhibiting DHT ligand synt
Externí odkaz: https://doaj.org/article/48d7906d178649039aa035689256638e
Zobrazit plný text záznamu
4
Akademický článek
Chemotherapy-induced monoamine oxidase expression in prostate carcinoma functions as a cytoprotective resistance enzyme and associates with clinical outcomes.
Autor: Ryan R Gordon, Mengchu Wu, Chung-Ying Huang, William P Harris, Hong Gee Sim, Jared M Lucas, Ilsa Coleman, Celestia S Higano, Roman Gulati, Lawrence D True, Robert Vessella, Paul H Lange, Mark Garzotto, Tomasz M Beer, Peter S Nelson
Publikováno v: PLoS ONE, Vol 9, Iss 9, p e104271 (2014)
To identify molecular alterations in prostate cancers associating with relapse following neoadjuvant chemotherapy and radical prostatectomy patients with high-risk localized prostate cancer were enrolled into a phase I-II clinical trial of neoadjuvan
Externí odkaz: https://doaj.org/article/c8ef072dd8bc4f929d1d56a4959eebdd
Zobrazit plný text záznamu
5
Akademický článek
A three-marker FISH panel detects more genetic aberrations of AR, PTEN and TMPRSS2/ERG in castration-resistant or metastatic prostate cancers than in primary prostate tumors.
Autor: Xiaoyu Qu, Grace Randhawa, Cynthia Friedman, Brenda F Kurland, Lena Glaskova, Ilsa Coleman, Elahe Mostaghel, Celestia S Higano, Christopher Porter, Robert Vessella, Peter S Nelson, Min Fang
Publikováno v: PLoS ONE, Vol 8, Iss 9, p e74671 (2013)
TMPRSS2/ERG rearrangement, PTEN gene deletion, and androgen receptor (AR) gene amplification have been observed in various stages of human prostate cancer. We hypothesized that using these markers as a combined panel would allow better differentiatio
Externí odkaz: https://doaj.org/article/9f8c504a0ae34003bca40fbcfd8c042e
Zobrazit plný text záznamu
6
Akademický článek
Randomized, Open-Label Phase 2 Study of Apalutamide plus Androgen Deprivation Therapy versus Apalutamide Monotherapy versus Androgen Deprivation Monotherapy in Patients with Biochemically Recurrent Prostate Cancer
Autor: Rahul Aggarwal, Joshi J. Alumkal, Russell Z. Szmulewitz, Celestia S. Higano, Alan H. Bryce, Angela Lopez-Gitlitz, Sharon A. McCarthy, Branko Miladinovic, Kelly McQuarrie, Shibu Thomas, Ke Zhang, Eric J. Small
Publikováno v: Prostate Cancer, Vol 2022 (2022)
Purpose. This randomized phase 2 study sought to assess the treatment effect of a finite duration of apalutamide with and without androgen deprivation therapy (ADT) in biochemically recurrent prostate cancer (BCR PC). Materials and Methods. Patients
Externí odkaz: https://doaj.org/article/ca0c2ba8c68e4aca981effd45231b1a2
Zobrazit plný text záznamu
8
A randomized comparison of group mindfulness and group cognitive behavioral therapy vs control for couples after prostate cancer with sexual dysfunction
Autor: Bibiana M Kemerer, Bozena Zdaniuk, Celestia S Higano, Jennifer A Bossio, Raysa Camara Bicalho Santos, Ryan Flannigan, Lori A Brotto
Publikováno v: The Journal of Sexual Medicine. 20:346-366
BackgroundSexual dysfunction is the most common and most distressing consequence of prostate cancer (PCa) treatment and has been shown to directly affect the sexual function and quality of life of survivors’ partners. There are currently no establi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7d671f80e36316b261b86bab0b1c2eac
https://doi.org/10.1093/jsxmed/qdac038
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje