Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Celeste E. Reese"'
Autor:
Andreas Vogt, Billy W. Day, Dennis P. Curran, Neil A. Hukriede, John S. Lazo, Celeste E. Reese, Raghavan Balachandran, Hikmat N. Daghestani, Wei Zhu, Daniel P. Camarco, Maria Jiménez, Laura L. Vollmer
The natural product (−)-dictyostatin is a microtubule-stabilizing agent that potently inhibits the growth of human cancer cells, including paclitaxel-resistant clones. Extensive structure–activity relationship studies have revealed several region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecdf80d5efb235382c6a7baaca49a0a2
https://doi.org/10.1158/1535-7163.c.6535479
https://doi.org/10.1158/1535-7163.c.6535479
Autor:
Andreas Vogt, Billy W. Day, Dennis P. Curran, Neil A. Hukriede, John S. Lazo, Celeste E. Reese, Raghavan Balachandran, Hikmat N. Daghestani, Wei Zhu, Daniel P. Camarco, Maria Jiménez, Laura L. Vollmer
Supplementary Tables 1-2,Characterization Data & References from A Simplified Synthesis of Novel Dictyostatin Analogues with In Vitro Activity against Epothilone B–Resistant Cells and Antiangiogenic Activity in Zebrafish Embryos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32fec54cded103cf86b1a690df8d0627
https://doi.org/10.1158/1535-7163.22497030.v1
https://doi.org/10.1158/1535-7163.22497030.v1
Autor:
Andreas Vogt, Billy W. Day, Dennis P. Curran, Neil A. Hukriede, John S. Lazo, Celeste E. Reese, Raghavan Balachandran, Hikmat N. Daghestani, Wei Zhu, Daniel P. Camarco, Maria Jiménez, Laura L. Vollmer
NMR Spectra from A Simplified Synthesis of Novel Dictyostatin Analogues with In Vitro Activity against Epothilone B–Resistant Cells and Antiangiogenic Activity in Zebrafish Embryos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45de1697f469204b948471244ec8f90e
https://doi.org/10.1158/1535-7163.22497033
https://doi.org/10.1158/1535-7163.22497033
Autor:
Anupma Jha, Tong Ying Shun, Dillon C. Gavlock, Vijay Yechoor, Vineet Mahajan, Daniel E. Lefever, Xiang Li, Alejandro Soto-Gutierrez, Lawrence Vernetti, Jaideep Behari, D. Lansing Taylor, Albert Gough, Erin E. Kershaw, Celeste E. Reese, Richard DeBiasio, Manush Saydmohammed, Mark T. Miedel, Andrew M. Stern
Publikováno v:
Exp Biol Med (Maywood)
Metabolic syndrome is a complex disease that involves multiple organ systems including a critical role for the liver. Non-alcoholic fatty liver disease (NAFLD) is a key component of the metabolic syndrome and fatty liver is linked to a range of metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cbce253b16728f7163251422a3bba7d
https://doi.org/10.1177/15353702211009228
https://doi.org/10.1177/15353702211009228
Autor:
Albert H Gough, Ning Chen, Tong Ying Shun, Timothy R Lezon, Robert C Boltz, Celeste E Reese, Jacob Wagner, Lawrence A Vernetti, Jennifer R Grandis, Adrian V Lee, Andrew M Stern, Mark E Schurdak, D Lansing Taylor
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102678 (2014)
One of the greatest challenges in biomedical research, drug discovery and diagnostics is understanding how seemingly identical cells can respond differently to perturbagens including drugs for disease treatment. Although heterogeneity has become an a
Externí odkaz:
https://doaj.org/article/073440165ed34f8b8cced8d70b8f685a
Autor:
Alan Valdiviezo, Mark E. Schurdak, Courtney Sakolish, Weihsueh A. Chiu, D. Lansing Taylor, Celeste E. Reese, Ivan Rusyn, Yu-Syuan Luo, Albert Gough, Lawrence Vernetti
Publikováno v:
Toxicology
A human microfluidic four-cell liver acinus microphysiology system (LAMPS), was evaluated for reproducibility and robustness as a model for drug pharmacokinetics and toxicology. The model was constructed using primary human hepatocytes or human induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79a12f247dcee950019c3d25b32acae1
https://pubmed.ncbi.nlm.nih.gov/33307106
https://pubmed.ncbi.nlm.nih.gov/33307106
Autor:
Tongying Shun, Celeste E. Reese, Crystal D. Zellefrow, Ana Lira, Joel S. Greenberger, Elizabeth R. Sharlow, John S. Lazo, Michael W. Epperly
Publikováno v:
Radiation research. 178(3)
Currently, there is a serious absence of pharmaceutically attractive small molecules that mitigate the lethal effects of an accidental or intentional public exposure to toxic doses of ionizing radiation. Moreover, cellular systems that emulate the ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a63b02a85efc2b41379a0b5a1594db55
https://pubmed.ncbi.nlm.nih.gov/22747550
https://pubmed.ncbi.nlm.nih.gov/22747550
Autor:
Wei Zhu, Neil A. Hukriede, Billy W. Day, Hikmat N. Daghestani, María Jiménez, Laura L. Vollmer, Raghavan Balachandran, Daniel P. Camarco, Dennis P. Curran, Andreas Vogt, Celeste E. Reese, John S. Lazo
Publikováno v:
Molecular cancer therapeutics. 10(6)
The natural product (−)-dictyostatin is a microtubule-stabilizing agent that potently inhibits the growth of human cancer cells, including paclitaxel-resistant clones. Extensive structure–activity relationship studies have revealed several region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196c1b13c8417a2f1dc0afb3cc99d4bf
https://pubmed.ncbi.nlm.nih.gov/21490306
https://pubmed.ncbi.nlm.nih.gov/21490306
Autor:
Laura L. Vollmer, John S. Lazo, Eckhard Günther, Chad D. Hopkins, Carolyn A. Kitchens, Peter Wipf, Andreas Vogt, Celeste E. Reese, Thomas H. Graham
Disorazoles are macrocyclic polyketides first isolated from the fermentation broth of the myxobacterium Sorangium cellulosum. Both the major fermentation product disorazole A1 and its much rarer companion disorazole C1 exhibit potent cytotoxic activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a551e50326c7cb5d1eeb28313f8eb610
https://europepmc.org/articles/PMC2835430/
https://europepmc.org/articles/PMC2835430/
Autor:
Bethany Petrik, John S. Lazo, Billy W. Day, Raghavan Balachandran, Carolyn A. Kitchens, Brianne S. Raccor, Jane R. Stout, Peter Wipf, Fengfeng L. Xu, Marni Brisson Tierno, Thomas H. Graham, Celeste E. Reese, William S. Saunders, Claire E. Walczak, Alexander P. Ducruet
Disorazoles comprise a family of 29 macrocyclic polyketides isolated from the fermentation broth of the myxobacterium Sorangium cellulosum. The major fermentation product, disorazole A(1), was found previously to irreversibly bind to tubulin and to h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485e802de4275d3e915fdfd0842dfd6d
https://europepmc.org/articles/PMC2649750/
https://europepmc.org/articles/PMC2649750/