Zobrazeno 1 - 10 of 235 pro vyhledávání: '"Celeste C Finnerty"'
1
Akademický článek
Biventricular differences in β-adrenergic receptor signaling following burn injury.
Autor: Ashley N Guillory, Robert P Clayton, Anesh Prasai, Amina El Ayadi, David N Herndon, Celeste C Finnerty
Publikováno v: PLoS ONE, Vol 12, Iss 12, p e0189527 (2017)
Burn injury detrimentally affects the myocardium, primarily due to over-activation of β-adrenergic receptors (β-AR). Autopsy reports from our institution reveal that patients often suffer from right ventricle (RV) failure. Since burn injury affects
Externí odkaz: https://doaj.org/article/21fdfb3c506c49748d6c356982fbe795
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2
Akademický článek
The effect of ketoconazole on post-burn inflammation, hypermetabolism and clinical outcomes.
Autor: Marc G Jeschke, Felicia N Williams, Celeste C Finnerty, Noe A Rodriguez, Gabriela A Kulp, Arny Ferrando, William B Norbury, Oscar E Suman, Robert Kraft, Ludwik K Branski, Ahmed M Al-mousawi, David N Herndon
Publikováno v: PLoS ONE, Vol 7, Iss 5, p e35465 (2012)
Hypercortisolemia has been suggested as a primary hormonal mediator of whole-body catabolism following severe burn injury. Ketoconazole, an anti-fungal agent, inhibits cortisol synthesis. We, therefore, studied the effect of ketoconazole on post-burn
Externí odkaz: https://doaj.org/article/06d969f76c714147a1aa3dd1dd2843d5
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3
Akademický článek
Long-term persistance of the pathophysiologic response to severe burn injury.
Autor: Marc G Jeschke, Gerd G Gauglitz, Gabriela A Kulp, Celeste C Finnerty, Felicia N Williams, Robert Kraft, Oscar E Suman, Ronald P Mlcak, David N Herndon
Publikováno v: PLoS ONE, Vol 6, Iss 7, p e21245 (2011)
Main contributors to adverse outcomes in severely burned pediatric patients are profound and complex metabolic changes in response to the initial injury. It is currently unknown how long these conditions persist beyond the acute phase post-injury. Th
Externí odkaz: https://doaj.org/article/d2b24082af6d4bd889c16fb94315c5b4
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6
Perceptions of patient disease burden and management approaches in systemic mastocytosis: Results of the TouchStone Healthcare Provider Survey
Autor: Ruben A. Mesa, Erin M. Sullivan, David Dubinski, Brittany Carroll, Valerie M. Slee, Susan V. Jennings, Celeste C. Finnerty, Linda S. Bohannon, Susan D. Mathias, Betsy J. Lahue, Mariana C. Castells
Publikováno v: Cancer. 128(20)
Systemic mastocytosis (SM) is a rare clonal neoplasm driven by the KIT D816V mutation and has a broad range of debilitating symptoms. In this study, the authors evaluated SM disease perceptions and management strategies among US health care providers
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127542b856aee4cf99940ceedc9739e4
https://pubmed.ncbi.nlm.nih.gov/35996860
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7
Standards in Biologic Lesions: Cutaneous Thermal Injury and Inhalation Injury Working Group 2018 Meeting Proceedings
Autor: Heather M. Powell, Matthias Majetschak, Madrzykowski D, Celeste C. Finnerty, Gibson Alf, Charles E. Wade, Jeffrey W. Shupp, L C Cancio, Lauren T. Moffatt, Mashkoor A. Choudhry, Elizabeth J. Kovacs
Publikováno v: Journal of Burn Care & Research: Official Publication of the American Burn Association
On August 27 and 28, 2018, the American Burn Association, in conjunction with Underwriters Laboratories, convened a group of experts on burn and inhalation injury in Washington, DC. The goal of the meeting was to identify and discuss the existing kno
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f23e6a36c6ff4b66133f14fda0cd37
http://europepmc.org/articles/PMC7195554
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8
P53(Cp44), an Endogenous Human p53 Fragment Generated via M-Calpain-Mediated Cleavage Beyond Degradation
Autor: Paul J. Boor, Thomas Albrecht, Celeste C. Finnerty, Zhenping Chen
Publikováno v: Gastroenterology Pancreatology and Hepatobilary Disorders. 3:01-06
Endogenous fragments of p53 identified recently in human cytomegalovirus (HCMV)-infected human lung fibroblasts, specifically a ~44-kDa N- terminal fragment referred to as p53(Cp44), have been shown to be generated via m-calpain cleavage. p53(C
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14ec0ef3e76a793bf0b0286e8bcd0240
https://doi.org/10.31579/2641-5194/023
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9
Effect of N-(2-aminoethyl) ethanolamine on hypertrophic scarring changes in vitro: Finding novel anti-fibrotic therapies
Autor: Celeste C. Finnerty, Jianhua Gu, Amina El Ayadi, Paul J. Boor, Linda E. Sousse, Zhenping Chen, David N. Herndon, Jia Zhou, Andres F. Oberhauser
Publikováno v: Toxicology and Applied Pharmacology. 362:9-19
Hypertrophic scars (HS) limit movement, decrease quality of life, and remain a major impediment to rehabilitation from burns. However, no effective pharmacologic therapies for HS exist. Here we tested the in vitro anti-fibrotic effects of the novel c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f80d0b870c2ce11c739e99aca572c2
https://doi.org/10.1016/j.taap.2018.09.026
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10
Calpain-mediated cleavage of p53 in human cytomegalovirus-infected lung fibroblasts
Autor: Celeste C. Finnerty, David N. Herndon, Paul J. Boor, Thomas Albrecht, Zhenping Chen
Publikováno v: FASEB bioAdvances
Endogenous fragments of p53 protein were identified in human cytomegalovirus (HCMV)‐infected human lung fibroblasts, particularly a 44‐kDa N‐terminal fragment [hereafter referred to as p53(ΔCp44)], generated via calpain cleavage. The fragment
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0460b568cf466e22c2f7146ad5c8bd13
https://doi.org/10.1096/fba.1028
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