Structure of the human NK cell NKR-P1:LLT1 receptor:ligand complex reveals clustering in the immune synapse

Autor: Jan Bláha, Tereza Skálová, Barbora Kalousková, Ondřej Skořepa, Denis Cmunt, Valéria Grobárová, Samuel Pazicky, Edita Poláchová, Celeste Abreu, Jan Stránský, Tomáš Kovaľ, Jarmila Dušková, Yuguang Zhao, Karl Harlos, Jindřich Hašek, Jan Dohnálek, Ondřej Vaněk

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)

NKR-P1 is an inhibitory receptor on the surface of natural killer cells, and its engagement with the ligand LLT1 on activated monocytes and B cells triggers NK cell self-tolerance and other immunological processes. Here authors set up a comprehensive

Externí odkaz: https://doaj.org/article/2886da344a5c4fb5b7cd879fe5b82c44

Tumor Marker B7-H6 Bound to the Coiled Coil Peptide-Polymer Conjugate Enables Targeted Therapy by Activating Human Natural Killer Cells

Autor: Barbora Kalousková, Ondřej Skořepa, Denis Cmunt, Celeste Abreu, Kateřina Krejčová, Jan Bláha, Irena Sieglová, Vlastimil Král, Milan Fábry, Robert Pola, Michal Pechar, Ondřej Vaněk

Publikováno v: Biomedicines, Vol 9, Iss 11, p 1597 (2021)

Targeted cancer immunotherapy is a promising tool for restoring immune surveillance and eradicating cancer cells. Hydrophilic polymers modified with coiled coil peptide tags can be used as universal carriers designed for cell-specific delivery of suc

Externí odkaz: https://doaj.org/article/2c9043d3a1e7484f806ef4bdcff6e30e

Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith: a multi laboratory benchmark study

Autor: Caroline Mas, Grzegorz Piszczek, Marjetka Podobnik, Kathryn Perez, Timothy Sharpe, Stephen H. McLaughlin, Roland Montserret, Stefan H. Knauer, Bruno Baron, Christopher M. Johnson, Quyen Nguyen, Mark A. Williams, Katja Pirc, Arthur Sedivy, Celeste Abreu, Tina Daviter, David Ortega-Alarcon, Daumantas Matulis, Rouba Nasreddine, Carlo Carolis, Thomas A. Jowitt, Stephan Uebel, David Staunton, Andrew P. Leech, Maria Garcia-Alai, June Southall, Alexander Fish, Jitka Holková, Alexander K. Buell, Michael Weyand, Jasmina Rokov-Plavec, Blanca López-Méndez, Sylvie Berger, Josef Houser, Natalia Rodrigo, Wojciech Bal, Chad A. Brautigam, Josef Hamacek, Reine Nehmé, Olga Abian, Christian Guenther, Ondrej Vanek, Susanne Schaefer, Sharon M. Kelly, Malgorzata Adamczyk, Di Wu, Pedro Tavares

Publikováno v: European Biophysics Journal
European Biophysics Journal, Springer Verlag (Germany), 2021, 50 (3-4), pp.411-427. ⟨10.1007/s00249-021-01532-6⟩
European biophysics journal, New York : Springer, 2021, vol. 50, iss. 3-4, p. 411-427
European Biophysics Journal, 2021, 50 (3-4), pp.411-427. ⟨10.1007/s00249-021-01532-6⟩
López-Méndez, B, Baron, B, Brautigam, C A, Jowitt, T A, Knauer, S H, Uebel, S, Williams, M A, Sedivy, A, Abian, O, Abreu, C, Adamczyk, M, Bal, W, Berger, S, Buell, A K, Carolis, C, Daviter, T, Fish, A, Garcia-Alai, M, Guenther, C, Hamacek, J, Holková, J, Houser, J, Johnson, C, Kelly, S, Leech, A, Mas, C, Matulis, D, McLaughlin, S H, Montserret, R, Nasreddine, R, Nehmé, R, Nguyen, Q, Ortega-Alarcón, D, Perez, K, Pirc, K, Piszczek, G, Podobnik, M, Rodrigo, N, Rokov-Plavec, J, Schaefer, S, Sharpe, T, Southall, J, Staunton, D, Tavares, P, Vanek, O, Weyand, M & Wu, D 2021, ' Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith : a multi laboratory benchmark study ', European Biophysics Journal, vol. 50, pp. 411-427 . https://doi.org/10.1007/s00249-021-01532-6
López-Méndez, B, Baron, B, Brautigam, C A, Jowitt, T A, Knauer, S H, Uebel, S, Williams, M A, Sedivy, A, Abian, O, Abreu, C, Adamczyk, M, Bal, W, Berger, S, Büll, A K, Carolis, C, Daviter, T, Fish, A, Garcia-Alai, M, Guenther, C, Hamacek, J, Holková, J, Houser, J, Johnson, C, Kelly, S, Leech, A, Mas, C, Matulis, D, McLaughlin, S H, Montserret, R, Nasreddine, R, Nehmé, R, Nguyen, Q, Ortega-Alarcón, D, Perez, K, Pirc, K, Piszczek, G, Podobnik, M, Rodrigo, N, Rokov-Plavec, J, Schaefer, S, Sharpe, T, Southall, J, Staunton, D, Tavares, P, Vanek, O, Weyand, M & Wu, D 2021, ' Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith: a multi laboratory benchmark study ', European Biophysics Journal, vol. 50, pp. 411-417 . https://doi.org/10.1007/s00249-021-01532-6

Microscale thermophoresis (MST), and the closely related Temperature Related Intensity Change (TRIC), are synonyms for a recently developed measurement technique in the field of biophysics to quantify biomolecular interactions, using the (capillary-b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6fc4f92b25cca54d92fe47a2fc8c579
http://europepmc.org/articles/PMC8519905

Natural killer cell-based strategies for immunotherapy of cancer

Autor: Ondřej Vaněk, Barbora Kalousková, Celeste Abreu, Shiva Nejadebrahim, Ondřej Skořepa

Publikováno v: Immunotherapeutics ISBN: 9780323992275

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de9a3ab0c1d30c32eb5a5b8918295eb8
https://doi.org/10.1016/bs.apcsb.2022.02.001

Formación docente y escuela: posibles articulaciones

Autor: Celeste Abréu Van Grieken

Publikováno v: Ciencia y Sociedad, Vol 41, Iss 1 (2016)

Este artículo pretende suscitar una reflexión sobre la articulación entre formación docente, escuela y contexto. Analiza la formación docente en perspectiva de la construcción de nuevas subjetividades y del rol de los docentes desde una epistem

Externí odkaz: https://doaj.org/article/2c72c54873ed4f7298c810a02a7bb7a6