Zobrazeno 1 - 10
of 3 471
pro vyhledávání: '"Celastrol"'
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Prostate cancer (PCa) is a leading malignancy among men globally, with rising incidence rates emphasizing the critical need for better detection and therapeutic approaches. The roles of HSP90AB1 and PARP1 in prostate cancer cells
Externí odkaz:
https://doaj.org/article/df19228ae1aa4ae3a4eac0a5fd55d607
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 9613-9635 (2024)
Xueya Xu,* Weili Lu,* Hua Zhang, Xiaoying Wang, Caixia Huang, Qiuping Huang, Wen Xu, Wei Xu Pharmacy College, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, People’s Republic of China*These authors contributed equall
Externí odkaz:
https://doaj.org/article/89c43b0d68eb4b1ebeb2f16bca9aad0d
Autor:
Min Wei, Yi Liu, Dongsheng Li, Xingdong Wang, Xiaodong Wang, Yuping Li, Zhengcun Yan, Hengzhu Zhang
Publikováno v:
IBRO Neuroscience Reports, Vol 17, Iss , Pp 161-176 (2024)
Background: Following recent research advancements, an increasing level of evidence had been published to indicate that celastrol exerted a therapeutic effect on a range of nervous system diseases. This study therefore aimed to investigate the potent
Externí odkaz:
https://doaj.org/article/4c2fa24305574465a8cb5bf7506b53c4
Autor:
Jinfeng Shi, Jiahui Zhou, Bo Liu, Kezhou Lin, Xingliang Xie, Xue Han, Yanmei Sheng, Yihan Liu, Congjian He, Yujin Zhou, Nan Zhu, Qian Yang, Ruifeng Luo, Yi Li
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background The oral administration of drugs for treating ulcerative colitis (UC) is hindered by several factors, including inadequate gastrointestinal stability, insufficient accumulation in colonic lesions, and uncontrolled drug release. Me
Externí odkaz:
https://doaj.org/article/1af3438f6ea34254b9e0d47215d5f6b1
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 3121-3141 (2024)
Banglan Cai,1,2,* Manman Qi,2,3,* Xue Zhang,1,2 Denghai Zhang1– 3 1School of Basic Medicine, Ningxia Medical University, Yinchuan, People’s Republic of China; 2Shanghai Health Commission Key Laboratory of Artificial Intelligence (AI)-Base
Externí odkaz:
https://doaj.org/article/b87de92c7d1c48b586bd2970b4515b95
Publikováno v:
Journal of Traditional Chinese Medical Sciences, Vol 11, Iss 3, Pp 330-339 (2024)
Objective: To investigate the pyroptosis-inducing effects of celastrol on tumor cells and to explore the potential mechanisms involved, specifically focusing on the role of the caspase-3/gasdermin E (GSDME) signaling pathway and the impact of endopla
Externí odkaz:
https://doaj.org/article/a673290a4c6e4e97825b91926ee63531
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 5707-5718 (2024)
Bo Wang,1,2 Jiquan Shen,2 Changjian Zhou,2 Xinggao Wang,2 Shuanghu Wang,3 Ruixing Hou1 1Department of Orthopaedics, Suzhou Ruihua Orthopedic Hospital Affiliated Suzhou Medical College of Soochow University, Suzhou, Jiangsu, 215000, People’s Republi
Externí odkaz:
https://doaj.org/article/0bd2de0655aa491a87157da901e2b83e
Publikováno v:
Bioactive Materials, Vol 36, Iss , Pp 83-95 (2024)
Abnormal proliferation of aggressive fibroblast-like synoviocytes (FLS) and perpetuate synovial inflammation can inevitably accelerate the progression of rheumatoid arthritis (RA). Herein, a strategy of simultaneously promoting FLS apoptosis and inhi
Externí odkaz:
https://doaj.org/article/4a66ba84ac64424cb7dfcb80de756935
Autor:
Peramaiyan Rajendran, Kaviyarasi Renu, Enas M. Ali, Marwa Azmy M. Genena, Vishnupriya Veeraraghavan, Ramya Sekar, Ashok Kumar Sekar, Sujatha Tejavat, Parthasarathi Barik, Basem M. Abdallah
Publikováno v:
Immunity, Inflammation and Disease, Vol 12, Iss 10, Pp n/a-n/a (2024)
Abstract Background Phytochemicals possess a wide range of anti‐tumor properties, including the modulation of autophagy and regulation of programmed cell death. Autophagy is a critical process in cellular homeostasis and its dysregulation is associ
Externí odkaz:
https://doaj.org/article/109b17475c2244a1ada998fae4ba095a
Autor:
Ping Zhao, Xing-Bo He, Xin-Yue Chen, Zhang-Long Li, Wen-Jia Xing, Wei Liu, Cong Ren, Xu-Dong Han, Bin Guo
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Objective Melanoma, with its high degree of malignancy, stands as one of the most dangerous skin cancers and remains the primary cause of death from skin cancer. With studies demonstrating the potential of traditional Chinese medicine to int
Externí odkaz:
https://doaj.org/article/f37f2abb61a44b089f76cc9d4c931b50