Zobrazeno 1 - 10
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pro vyhledávání: '"Cejka P"'
Anomaly detection in network traffic is crucial for maintaining the security of computer networks and identifying malicious activities. One of the primary approaches to anomaly detection are methods based on forecasting. Nevertheless, extensive real-
Externí odkaz:
http://arxiv.org/abs/2409.18874
Network traffic monitoring based on IP Flows is a standard monitoring approach that can be deployed to various network infrastructures, even the large IPS-based networks connecting millions of people. Since flow records traditionally contain only lim
Externí odkaz:
http://arxiv.org/abs/2310.05530
Network traffic monitoring using IP flows is used to handle the current challenge of analyzing encrypted network communication. Nevertheless, the packet aggregation into flow records naturally causes information loss; therefore, this paper proposes a
Externí odkaz:
http://arxiv.org/abs/2307.13434
Autor:
Tomoki Tamai, Giordano Reginato, Ryusei Ojiri, Issei Morita, Alexandra Avrutis, Petr Cejka, Miki Shinohara, Katsunori Sugimoto
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract DNA double-strand breaks (DSBs) must be repaired to ensure cell survival and genomic integrity. In yeast, the Mre11-Rad50-Xrs2 complex (MRX) collaborates with Sae2 to initiate DSB repair. Sae2 stimulates two MRX nuclease activities, endonucl
Externí odkaz:
https://doaj.org/article/acbba23eb49746468174a70b6864e030
Autor:
Nicola Moser, Floran Sahiti, Götz Gelbrich, Vladimir Cejka, Fabian Kerwagen, Judith Albert, Stefan Frantz, Peter U. Heuschmann, Stefan Störk, Caroline Morbach
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Knowledge about a patient’s physical fitness can aid in medical decision-making, but objective assessment can be challenging and time-consuming. We aimed to investigate the concordance of self-reported health status and physical functionin
Externí odkaz:
https://doaj.org/article/85a36bec541e40018361a6ead38c8594
Autor:
Giordano Reginato, Maria Rosaria Dello Stritto, Yanbo Wang, Jingzhou Hao, Raphael Pavani, Michael Schmitz, Swagata Halder, Vincent Morin, Elda Cannavo, Ilaria Ceppi, Stefan Braunshier, Ananya Acharya, Virginie Ropars, Jean-Baptiste Charbonnier, Martin Jinek, Andrè Nussenzweig, Taekjip Ha, Petr Cejka
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The outcome of CRISPR-Cas-mediated genome modifications is dependent on DNA double-strand break (DSB) processing and repair pathway choice. Homology-directed repair (HDR) of protein-blocked DSBs requires DNA end resection that is initiated b
Externí odkaz:
https://doaj.org/article/9468f29a4c104f0db450028e4975e766
Recent network traffic classification methods benefitfrom machine learning (ML) technology. However, there aremany challenges due to use of ML, such as: lack of high-qualityannotated datasets, data-drifts and other effects causing aging ofdatasets an
Externí odkaz:
http://arxiv.org/abs/2211.08399
Autor:
Ananya Acharya, Hélène Bret, Jen-Wei Huang, Martin Mütze, Martin Göse, Vera Maria Kissling, Ralf Seidel, Alberto Ciccia, Raphaël Guérois, Petr Cejka
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract HROB promotes the MCM8-9 helicase in DNA damage response. To understand how HROB activates MCM8-9, we defined their interaction interface. We showed that HROB makes important yet transient contacts with both MCM8 and MCM9, and binds the MCM8
Externí odkaz:
https://doaj.org/article/f907eefa14ff4cc6a2a975c93ecb0f6b
Autor:
Lorenzo Galanti, Martina Peritore, Robert Gnügge, Elda Cannavo, Johannes Heipke, Maria Dilia Palumbieri, Barbara Steigenberger, Lorraine S. Symington, Petr Cejka, Boris Pfander
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract DNA double-strand breaks (DSBs) can be repaired by several pathways. In eukaryotes, DSB repair pathway choice occurs at the level of DNA end resection and is controlled by the cell cycle. Upon cell cycle-dependent activation, cyclin-dependen
Externí odkaz:
https://doaj.org/article/8bcb57ff610c4ff79e3b5f638390ffcf
Autor:
Floran Sahiti, Vladimir Cejka, Lena Schmidbauer, Judith Albert, Fabian Kerwagen, Stefan Frantz, Götz Gelbrich, Peter U. Heuschmann, Stefan Störk, Caroline Morbach
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 12 (2024)
Background The incidental finding of a pericardial effusion (PE) poses a challenge in clinical care. PE is associated with malignant conditions or severe cardiac disease but may also be observed in healthy individuals. This study explored the prevale
Externí odkaz:
https://doaj.org/article/2c490f3bb5de415492ea318754d577e7