Mathematical modeling of the thermal effects of irreversible electroporation for in vitro, in vivo, and clinical use: a systematic review

Autor: Pierre Agnass, Eran van Veldhuisen, Martin J. C. van Gemert, Cees W. M. van der Geld, Krijn P. van Lienden, Thomas M. van Gulik, Martijn R. Meijerink, Marc G. Besselink, H. Petra Kok, Johannes Crezee

Publikováno v: International Journal of Hyperthermia, Vol 37, Iss 1, Pp 486-505 (2020)

Introduction Irreversible electroporation (IRE) is a relatively new ablation method for the treatment of unresectable cancers. Although the main mechanism of IRE is electric permeabilization of cell membranes, the question is to what extent thermal e

Externí odkaz: https://doaj.org/article/32bd84cd2df445f4ad9766615146f5b0

The Influence of a Metal Stent on the Distribution of Thermal Energy during Irreversible Electroporation.

Autor: Hester J Scheffer, Jantien A Vogel, Willemien van den Bos, Robert E Neal, Krijn P van Lienden, Marc G H Besselink, Martin J C van Gemert, Cees W M van der Geld, Martijn R Meijerink, John H Klaessens, Rudolf M Verdaasdonk

Publikováno v: PLoS ONE, Vol 11, Iss 2, p e0148457 (2016)

PURPOSE:Irreversible electroporation (IRE) uses short duration, high-voltage electrical pulses to induce cell death via nanoscale defects resulting from altered transmembrane potential. The technique is gaining interest for ablations in unresectable

Externí odkaz: https://doaj.org/article/7951d132e9a843809062d447e9381931

Maxwell's equations explain why irreversible electroporation will not heat up a metal stent

Autor: Cees W. M. van der Geld, Marc G. Besselink, Rudolf M. Verdaasdonk, Martijn R. Meijerink, Willemien van den Bos, Jantien A. Vogel, Ruben T. van Gaalen, Martin J. C. van Gemert, Hester J. Scheffer

Publikováno v: International Journal of Heat and Mass Transfer, 169:120962. Elsevier Ltd
International Journal of Heat and Mass Transfer, 169:120962. Elsevier
International journal of heat and mass transfer, 169:120962. Elsevier
International journal of heat and mass transfer, 169:120962. Elsevier Limited
van der Geld, C W M, van Gaalen, R T, Scheffer, H J, Vogel, J A, van den Bos, W, Meijerink, M R, Besselink, M G H, Verdaasdonk, R M & van Gemert, M J C 2021, ' Maxwell's equations explain why irreversible electroporation will not heat up a metal stent ', International Journal of Heat and Mass Transfer, vol. 169, 120962 . https://doi.org/10.1016/j.ijheatmasstransfer.2021.120962

Irreversible Electroporation (IRE) is a promising clinical ablation therapy for the treatment of cancer, but issues with the generation of heat must be solved before safe and effective clinical results can be obtained. In the present study, we show t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2fca431eb55c19c3982b322cbfa7ab
https://research.tue.nl/en/publications/abcf8b0b-cfbd-464f-b005-2601ce844075

Periocular CO2 laser resurfacing: severe ocular complications from multiple unintentional laser impacts on the protective metal eye shields

Autor: Wei-Yong Wang, H. A. Martino Neumann, Ton G. van Leeuwen, Rudy M.M.A. Nuijts, Martin J. C. van Gemert, Albert Wolkerstorfer, Cees W. M. van der Geld, Paul R. Bloemen, Hayri Hortoglu, Martine J. Jager, Daniel M. de Bruin

Publikováno v: Lasers in Surgery and Medicine. 50:980-986

Background and objectives A 36-year-old woman underwent CO2 laser resurfacing for periocular rhytides using protective stainless steel Cox II ocular shields. Immediately after the treatment, corneal lesions were seen in both eyes. The left eye subseq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74d522d1c3d30429687c8b6b237886f5
https://doi.org/10.1002/lsm.22951

Periocular CO

Autor: Martin J C, van Gemert, Paul R, Bloemen, Wei-Yong, Wang, Cees W M, van der Geld, Rudy M M A, Nuijts, Hayri, Hortoglu, Albert, Wolkerstorfer, Daniel M, de Bruin, Ton G, van Leeuwen, H A Martino, Neumann, Martine J, Jager

Publikováno v: Lasers in surgery and medicine. 50(10)

A 36-year-old woman underwent COWe estimated temperature-time combinations that could induce corneal injury and cataract. Heat conduction effects from a heated cornea to the lens and from a heated ring of periocular skin to the cornea were computed.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7ba961082861ef66cf4ea6e53f519ae1
https://pubmed.ncbi.nlm.nih.gov/29882233