Mycobacterial secretion systems ESX-1 and ESX-5 play distinct roles in host cell death and inflammasome activation

Autor: Cees J. Korbee, Louis Wilson, Karin de Punder, Jovanka Bestebroer, Peter J. Peters, Maaike van Zon, Wilbert Bitter, Tom H. M. Ottenhoff, Abdallah M. Abdallah, Nigel D. L. Savage, Astrid M. van der Sar, Nicole N. van der Wel

Publikováno v: Journal of immunology (Baltimore, Md., 187(9), 4744-4753. American Association of Immunologists
The Journal of Immunology
The Journal of Immunology; Vol 187
Journal of Immunology, 187(9), 4744-4753. American Association of Immunologists
Abdallah, A M, Bestebroer, J, Savage, N D L, de Punder, K, van Zon, M, Wilson, L, Korbee, C J, van der Sar, A M, Ottenhoff, T H M, van der Wel, N N, Bitter, W & Peters, P J 2011, ' Mycobacterial Secretion Systems ESX-1 and ESX-5 Play Distinct Roles in Host Cell Death and Inflammasome Activation ', Journal of Immunology, vol. 187, no. 9, pp. 4744-4753 . https://doi.org/10.4049/jimmunol.1101457
Journal of Immunology, 187(9), 4744-53
Journal of Immunology, 187(9), 4744-4753

During infection of humans and animals, pathogenic mycobacteria manipulate the host cell causing severe diseases such as tuberculosis and leprosy. To understand the basis of mycobacterial pathogenicity, it is crucial to identify the molecular virulen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5462811c67d107f166d61d8bc038b0f5
https://pubmed.ncbi.nlm.nih.gov/21957139