Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Cees F.M. Van Valkenburg"'
Publikováno v:
Journal of Neurochemistry. 39:990-997
A method, based on reverse-phase liquid-liquid chromatography, has been developed for the determination, in a single run, of dopamine (DA) and its acidic metabolites 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA), combined with el
Publikováno v:
Life Sciences. 28:973-981
Rats received 7 daily injections with baclofen (40 mg/kg), GBL (750 mg/kg) or HA-966 (100 mg/kg). Dopamine (DA) was measured in the striatum and olfactory tubercle (OT) of rats, sacrificed 0.5 h or 1 h after the last injection. Marked tolerance and c
Publikováno v:
European Journal of Pharmacology. 158:29-35
Repeated administration of 1-hydroxy-3-amino-pyrolidone-2 (HA-966) to rats induces tolerance, as shown by a decreased, drug-stimulated accumulation of dopamine (DA) in the striatum. In the present study we compared the adaptive response of the strati
Publikováno v:
European Journal of Pharmacology. 60:153-161
Acute injections of HA-966 (100 mg/kg) into rats caused a rapid elevation of dopamine (DA) content in the striatum. 3,4-Dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) levels increased after a latency period of 0.5 h and 1 h respective
Publikováno v:
European Journal of Pharmacology. 57:191-199
It is generally accepted that reserpine blocks the granular storage mechanism in catecholaminergic neurones and that (+)-amphetamine (AMP) releases dopamine (DA) from extragranular storage sites. In the present experiments it was investigated whether
Publikováno v:
Central Neurotransmitter Turnover ISBN: 9781461597803
Regional differences in drug effects on dopamine (DA) turnover are often taken as indications for differential effects in functional activity of the various dopaminergic systems. Functional activity of central dopaminergic neurones may be estimated b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42a112be3a56316fac401306cbfc7612
https://doi.org/10.1007/978-1-4615-9778-0_7
https://doi.org/10.1007/978-1-4615-9778-0_7
Publikováno v:
European journal of pharmacology. 48(2)
Striatal dopamine (DA) of rats increased twofold 1 h after blockade of DA release by either an electrolytic lesion of the substantia nigra (SN) or systemic administration of 1-hydroxy-3-amino-pyrrolidone-2 (HA-966). If the treatments were combined, n
Autor:
Jacques A. van der Krogt, Jacob de Jong, Hans van Berkum, Peter Moleman, U.R. Tjaden, Cees F.M. Van Valkenburg
Publikováno v:
Journal of neuroscience methods. 11(1)
A procedure to determine the specific activities (s.a.) of the putative neurotransmitter dopamine (DA) and its metabolites in rat striatum is described. For this purpose 200 μ Ci l -[3,5-3H]tyrosine was injected via a jugular vein cannula into freel