Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Ceereena Ubaida-Mohien"'
Autor:
Caglar Cosarderelioglu, Simion Kreimer, Alma I. Plaza‐Rodriguez, Pablo A. Iglesias, C. Conover Talbot, Helmy M. Siragy, Robert M. Carey, Ceereena Ubaida‐Mohien, Brian O'Rourke, Luigi Ferrucci, David A. Bennett, Jeremy Walston, Peter Abadir
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 18 (2023)
Background The renin‐angiotensin system plays a crucial role in human physiology, and its main hormone, angiotensin, activates 2 G‐protein–coupled receptors, the angiotensin type‐1 and type‐2 receptors, in almost every organ. However, contr
Externí odkaz:
https://doaj.org/article/c63cbfb65a3c494ba6fb143ad5cb0e65
Autor:
Roshni Roy, Pei-Lun Kuo, Julián Candia, Dimitra Sarantopoulou, Ceereena Ubaida-Mohien, Dena Hernandez, Mary Kaileh, Sampath Arepalli, Amit Singh, Arsun Bektas, Jaekwan Kim, Ann Z Moore, Toshiko Tanaka, Julia McKelvey, Linda Zukley, Cuong Nguyen, Tonya Wallace, Christopher Dunn, William Wood, Yulan Piao, Christopher Coletta, Supriyo De, Jyoti Sen, Nan-ping Weng, Ranjan Sen, Luigi Ferrucci
Publikováno v:
eLife, Vol 12 (2023)
Age-associated DNA methylation in blood cells convey information on health status. However, the mechanisms that drive these changes in circulating cells and their relationships to gene regulation are unknown. We identified age-associated DNA methylat
Externí odkaz:
https://doaj.org/article/d686b4020d774313aa1c545d7788c07b
Autor:
Robert A. Tumasian, Abhinav Harish, Gautam Kundu, Jen-Hao Yang, Ceereena Ubaida-Mohien, Marta Gonzalez-Freire, Mary Kaileh, Linda M. Zukley, Chee W. Chia, Alexey Lyashkov, William H. Wood, Yulan Piao, Christopher Coletta, Jun Ding, Myriam Gorospe, Ranjan Sen, Supriyo De, Luigi Ferrucci
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
As human skeletal muscle ages, gene expression programs change and reflect damage accumulation and homeostatic resilience mechanisms. Here, the authors present a detailed framework of the global transcriptome that characterizes skeletal muscle during
Externí odkaz:
https://doaj.org/article/fe1b133469394d2ea2f9de8c7479f7a6
Autor:
Ceereena Ubaida-Mohien, Sally Spendiff, Alexey Lyashkov, Ruin Moaddel, Norah J MacMillan, Marie-Eve Filion, Jose A Morais, Tanja Taivassalo, Luigi Ferrucci, Russell T Hepple
Publikováno v:
eLife, Vol 11 (2022)
Background: Master athletes (MAs) prove that preserving a high level of physical function up to very late in life is possible, but the mechanisms responsible for their high function remain unclear. Methods: We performed muscle biopsies in 15 octogena
Externí odkaz:
https://doaj.org/article/d70107ce73954db9be622478812cdc45
Autor:
Ceereena Ubaida-Mohien, Ruin Moaddel, Ann Zenobia Moore, Pei-Lun Kuo, Faraz Faghri, Ravi Tharakan, Toshiko Tanaka, Mike A. Nalls, Luigi Ferrucci
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Human aging is associated with a decline of physical and cognitive function and high susceptibility to chronic diseases, which is influenced by genetics, epigenetics, environmental, and socio-economic status. In order to identify the factors that mod
Externí odkaz:
https://doaj.org/article/6af8d2ecd1754008ad3de8448864ac3c
Autor:
Ceereena Ubaida-Mohien, Alexey Lyashkov, Marta Gonzalez-Freire, Ravi Tharakan, Michelle Shardell, Ruin Moaddel, Richard D Semba, Chee W Chia, Myriam Gorospe, Ranjan Sen, Luigi Ferrucci
Publikováno v:
eLife, Vol 8 (2019)
A decline of skeletal muscle strength with aging is a primary cause of mobility loss and frailty in older persons, but the molecular mechanisms of such decline are not understood. Here, we performed quantitative proteomic analysis from skeletal muscl
Externí odkaz:
https://doaj.org/article/8526b9711c14407e80591bd524a3eed5
Autor:
Ceereena Ubaida-Mohien, Marta Gonzalez-Freire, Alexey Lyashkov, Ruin Moaddel, Chee W. Chia, Eleanor M. Simonsick, Ranjan Sen, Luigi Ferrucci
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Muscle strength declines with aging and increasing physical activity is the only intervention known to attenuate this decline. In order to adequately investigate both preventive and therapeutic interventions against sarcopenia, a better understanding
Externí odkaz:
https://doaj.org/article/7c58d1cef94b476b95857a80d39ceee1
Autor:
Luigi Ferrucci, Julián Candia, Ceereena Ubaida-Mohien, Alexey Lyashkov, Nirad Banskota, Christiaan Leeuwenburgh, Stephanie Wohlgemuth, Jack M. Guralnik, Mary Kaileh, Dongxue Zhang, Robert Sufit, Supriyo De, Myriam Gorospe, Rachel Munk, Charlotte A. Peterson, Mary M. McDermott
Publikováno v:
Circulation Research. 132:1428-1443
Background: Few effective therapies exist to improve lower extremity muscle pathology and mobility loss due to peripheral artery disease (PAD), in part because mechanisms associated with functional impairment remain unclear. Methods: To better unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66a3e0318249a1701a0092770d6ec2b6
https://doi.org/10.1161/circresaha.122.322325
https://doi.org/10.1161/circresaha.122.322325
Autor:
Donnie Cameron, David A. Reiter, Fatemeh Adelnia, Ceereena Ubaida‐Mohien, Christopher M. Bergeron, Seongjin Choi, Kenneth W. Fishbein, Richard G. Spencer, Luigi Ferrucci
Publikováno v:
Aging Cell.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47e17a927898e3b4d723caabda27529f
https://doi.org/10.1111/acel.13851
https://doi.org/10.1111/acel.13851
Autor:
Ceereena Ubaida-Mohien, Toshiko Tanaka, Qu Tian, Zenobia Moore, Ruin Moaddel, Nathan Basisty, Eleanor M Simonsick, Luigi Ferrucci
Publikováno v:
Gerontology.
Measuring the abundance of biological molecules and their chemical modifications in blood and tissues has been the cornerstone of research and medical diagnoses for decades. Although the number and variety of molecules that can be measured have expan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae36434a4f6aa82980b23a48ead23872
https://doi.org/10.1159/000530795
https://doi.org/10.1159/000530795