Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Cedric Simillion"'
Autor:
Mahmoud Hallal, Sophie Braga-Lagache, Jovana Jankovic, Cedric Simillion, Rémy Bruggmann, Anne-Christine Uldry, Ramanjaneyulu Allam, Manfred Heller, Nicolas Bonadies
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-15 (2021)
Abstract Background Despite the introduction of targeted therapies, most patients with myeloid malignancies will not be cured and progress. Genomics is useful to elucidate the mutational landscape but remains limited in the prediction of therapeutic
Externí odkaz:
https://doaj.org/article/5de865060f1f4c709febcf28371fa294
Autor:
Florian Lipsmeier, Cedric Simillion, Atieh Bamdadian, Rosanna Tortelli, Lauren M Byrne, Yan-Ping Zhang, Detlef Wolf, Anne V Smith, Christian Czech, Christian Gossens, Patrick Weydt, Scott A Schobel, Filipe B Rodrigues, Edward J Wild, Michael Lindemann
Publikováno v:
Journal of Medical Internet Research, Vol 24, Iss 6, p e32997 (2022)
BackgroundRemote monitoring of Huntington disease (HD) signs and symptoms using digital technologies may enhance early clinical diagnosis and tracking of disease progression, guide treatment decisions, and monitor response to disease-modifying agents
Externí odkaz:
https://doaj.org/article/be7ef03add614a4cbbff46610a18dd00
Autor:
Annunziata Di Domenico, Christodoulos P. Pipinikas, Renaud S. Maire, Konstantin Bräutigam, Cedric Simillion, Matthias S. Dettmer, Erik Vassella, Chrissie Thirlwell, Aurel Perren, Ilaria Marinoni
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-11 (2020)
Di Domenico et al., provide a comprehensive assessment of DNA methylation in a large cohort of pancreatic neuroendocrine tumors. This work provides new insights into the epigenetic heterogeneity of the disease and cellular basis.
Externí odkaz:
https://doaj.org/article/a3f12048273d452cbac17af8d0e13581
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
Objective To identify distinctly regulated gene markers and enriched gene sets in breast tissue of cynomolgus monkeys (Macaca fascicularis) treated for six months with either conjugated equine estrogens (CEE) or estradiol (E2) by analysis of correspo
Externí odkaz:
https://doaj.org/article/4746d8c7bd074e8ab7c94a383d5ef679
Autor:
Kristina Krempaska, Sandra Barnowski, Jacopo Gavini, Nina Hobi, Simone Ebener, Cedric Simillion, Andrea Stokes, Ronja Schliep, Lars Knudsen, Thomas K. Geiser, Manuela Funke-Chambour
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-16 (2020)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a chronic fatal lung disease without a cure and new drug strategies are urgently needed. Differences in behavior between diseased and healthy cells are well known and drug response can be dif
Externí odkaz:
https://doaj.org/article/19ef359e4b5940cfae9770024a8b6cc1
Publikováno v:
Molecules, Vol 27, Iss 12, p 3935 (2022)
Ascites is a common complication of decompensated liver cirrhosis, and yet relatively little is known about its biochemical composition. We conducted two metabolomic investigations, comparing the profile of ascites from 33 cirrhotic patients and post
Externí odkaz:
https://doaj.org/article/59eefcf69a8d455b8f014402b6ad4c7f
Autor:
Giulio Loforese, Thomas Malinka, Adrian Keogh, Felix Baier, Cedric Simillion, Matteo Montani, Thanos D Halazonetis, Daniel Candinas, Deborah Stroka
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 1, Pp 46-60 (2017)
Abstract The liver has an intrinsic capacity to regenerate in response to injury or surgical resection. Nevertheless, circumstances in which hepatocytes are unresponsive to proliferative signals result in impaired regeneration and hepatic failure. As
Externí odkaz:
https://doaj.org/article/bb867698978741b1a93c15961be0af98
Autor:
Daniel Zysset, Benjamin Weber, Silvia Rihs, Jennifer Brasseit, Stefan Freigang, Carsten Riether, Yara Banz, Adelheid Cerwenka, Cedric Simillion, Pedro Marques-Vidal, Adrian F. Ochsenbein, Leslie Saurer, Christoph Mueller
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
TREM-1 is a receptor that amplifies acute pro-inflammatory responses in infection. Here the authors show that TREM-1 plays an important role in atherosclerosis, a chronic and non-infectious disease, by critically skewing myelopoiesis towards preferen
Externí odkaz:
https://doaj.org/article/c98d1cb4aaf840bdbe679de4d5413ba5
Autor:
Philip V'kovski, Markus Gerber, Jenna Kelly, Stephanie Pfaender, Nadine Ebert, Sophie Braga Lagache, Cedric Simillion, Jasmine Portmann, Hanspeter Stalder, Véronique Gaschen, Rémy Bruggmann, Michael H Stoffel, Manfred Heller, Ronald Dijkman, Volker Thiel
Publikováno v:
eLife, Vol 8 (2019)
Positive-sense RNA viruses hijack intracellular membranes that provide niches for viral RNA synthesis and a platform for interactions with host proteins. However, little is known about host factors at the interface between replicase complexes and the
Externí odkaz:
https://doaj.org/article/7bc36cf2cef34b898f15cc0116f17a65
Autor:
Luca Tamò, Kleanthis Fytianos, Fabienne Caldana, Cedric Simillion, Anis Feki, Izabela Nita, Manfred Heller, Thomas Geiser, Amiq Gazdhar
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 958 (2021)
Induced pluripotent stem cell secretome (iPSC-CM) mitigate organ injury and help in repair. Macrophages play a critical role in tissue repair and regeneration and can be directed to promote tissue repair by iPSC-CM, although the exact mechanisms are
Externí odkaz:
https://doaj.org/article/eb5d93a0ecd64ea59276c6ea13105ba8