Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Cedric R. Clapier"'
Autor:
Wen-Hao Zhang, Youpi Ye, Haiteng Deng, Zhucheng Chen, Hao Wu, Kangjing Chen, Cedric R. Clapier, Naveen Verma, Ning Gao, Bradley R. Cairns
Publikováno v:
Science
The architecture of the RSC complex RSC is a Snf2-family chromatin remodeler complex that controls the promoter architecture of most of the genes in yeast. Using single-particle cryo–electron microscopy, Ye et al. determined the structure of RSC bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f7a992c3d83ddd66451d8a6acae80f8
https://doi.org/10.1126/science.aay0033
https://doi.org/10.1126/science.aay0033
Autor:
Andreas H. Ehrensberger, Elodie Darbo, Aylin Cakiroglu, Nicholas M. Luscombe, Bradley R. Cairns, Cedric R. Clapier, Jesper Q. Svejstrup
Publikováno v:
Genome Research
Chromatin transactions are typically studied in vivo, or in vitro using artificial chromatin lacking the epigenetic complexity of the natural material. Attempting to bridge the gap between these approaches, we established a system for isolating the y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb82dc6d2114c0e3f62ffd36abbb40b1
https://doi.org/10.1101/gr.243139.118
https://doi.org/10.1101/gr.243139.118
Publikováno v:
Mol Cell
Summary SWI/SNF-family remodelers (BAF/PBAF in mammals) are essential chromatin regulators, and mutations in human BAF/PBAF components are associated with ∼20% of cancers. Cancer-associated missense mutations in human BRG1 (encoding the catalytic A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc5637b10ed6a0471d0920d6545e8ac2
https://europepmc.org/articles/PMC7853424/
https://europepmc.org/articles/PMC7853424/
Publikováno v:
Nat Rev Mol Cell Biol
Cells utilize diverse ATP-dependent nucleosome-remodelling complexes to carry out histone sliding, ejection or the incorporation of histone variants, suggesting that different mechanisms of action are used by the various chromatin-remodelling complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b6dc23d0869d9b20ebd37c5c4f1c97
https://doi.org/10.1038/nrm.2017.26
https://doi.org/10.1038/nrm.2017.26
Autor:
Cedric R. Clapier
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5578, p 5578 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The establishment and maintenance of genome packaging into chromatin contribute to define specific cellular identity and function. Dynamic regulation of chromatin organization and nucleosome positioning are critical to all DNA transactions—in parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::097d7c7d3fa120361c416c4e9aa65013
https://doi.org/10.3390/ijms22115578
https://doi.org/10.3390/ijms22115578
Autor:
Yongli Zhang, Bradley R. Cairns, Heather Szerlong, George Sirinakis, Margaret M. Kasten, Timothy J. Parnell, Cedric R. Clapier, Ramya Viswanathan
Publikováno v:
Molecular Cell. 62:453-461
The RSC chromatin remodeler slides and ejects nucleosomes, utilizing a catalytic subunit (Sth1) with DNA translocation activity, which can pump DNA around the nucleosome. A central question is whether and how DNA translocation is regulated to achieve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::211ec98acf88aed8469effefd9b48b39
https://doi.org/10.1016/j.molcel.2016.03.032
https://doi.org/10.1016/j.molcel.2016.03.032
Autor:
Cedric R. Clapier, Andreas H. Ehrensberger, Elodie Darbo, Aylin Cakiroglu, Jesper Q. Svejstrup, Nicholas M. Luscombe, Bradley R. Cairns
Chromatin transactions are typically studied in vivo, or in vitro using artificial chromatin lacking the epigenetic complexity of the natural material. Attempting to bridge the gap between these approaches, we established a system for isolating the y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f1c4096770cea2a66915edd1cf898e
https://hal.archives-ouvertes.fr/hal-01884309
https://hal.archives-ouvertes.fr/hal-01884309
Autor:
Bradley R. Cairns, Cedric R. Clapier
Publikováno v:
Nature
Chromatin-remodelling complexes (CRCs) mobilize nucleosomes to mediate the access of DNA-binding factors to their sites in vivo. These CRCs contain a catalytic subunit that bears an ATPase/DNA-translocase domain and flanking regions that bind nucleos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f044e03969fb889404757ce7e86f2e1
https://doi.org/10.1038/nature11625
https://doi.org/10.1038/nature11625
Autor:
George Sirinakis, Ying Gao, Cedric R. Clapier, Yongli Zhang, Bradley R. Cairns, Ramya Viswanathan
Publikováno v:
The EMBO Journal. 30:2364-2372
ATP‐dependent chromatin remodelling complexes use the energy of ATP hydrolysis to reposition and reconfigure nucleosomes. Despite their diverse functions, all remodellers share highly conserved ATPase domains, many shown to translocate DNA. Underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c10f3d2715a5864ced7406a11e906fa
https://doi.org/10.1038/emboj.2011.141
https://doi.org/10.1038/emboj.2011.141
Publikováno v:
Molecular and Cellular Biology. 21:875-883
The ATPase ISWI can be considered the catalytic core of several multiprotein nucleosome remodeling machines. Alone or in the context of nucleosome remodeling factor, the chromatin accessibility complex (CHRAC), or ACF, ISWI catalyzes a number of ATP-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcdf6fe500afa00a1f6b5505d04a80f6
https://doi.org/10.1128/mcb.21.3.875-883.2001
https://doi.org/10.1128/mcb.21.3.875-883.2001