Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Cedric Cagliero"'
Autor:
Ziyan Wang, Yang Gao, Manyu Luo, Cedric Cagliero, Hua Jiang, Yueqing Xie, Jianwei Zhu, Huili Lu
Publikováno v:
Bio-Protocol, Vol 9, Iss 18 (2019)
In comparison with full-length IgGs, antigen binding fragments (Fabs) are smaller in size and do not require the complexed post-translational modification. Therefore, Fab can be cost-effectively produced using an Escherichia coli (E. coli) expression
Externí odkaz:
https://doaj.org/article/a14b2926aa854b029ebb11048f25bcb0
Autor:
Kelsey Bettridge, Cedric Cagliero, Jie Xiao, Ding Jun Jin, Christopher H. Bohrer, Xiaoli Weng, Arvin Cesar Lagda
Publikováno v:
Proceedings of the National Academy of Sciences. 116:20115-20123
Recent studies have shown that RNA polymerase (RNAP) is organized into distinct clusters in Escherichia coli and Bacillus subtilis cells. Spatially organized molecular components in prokaryotic systems imply compartmentalization without the use of me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b60e23c2816b87ecbb8a98e3132f716
https://doi.org/10.1073/pnas.1903968116
https://doi.org/10.1073/pnas.1903968116
Autor:
Yuhong Zuo, Kevin S. Franco, Cedric Cagliero, Yan Ning Zhou, Mikhail Kashlev, Zhe Sun, Thomas D. Schneider, Chen Y, Ding Jun Jin
1AbstractInE. coli, one RNA polymerase (RNAP) transcribes all RNA species, and different regulons are transcribed by employing different sigma (σ) factors. RNAP containingσ38(σS) activates genes responding to stress conditions such as stationary p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d879fdca6921be08d1c312f08f16370a
Autor:
Jianwei Zhu, Jianrong Xu, Lei Han, Yueqing Xie, Cedric Cagliero, Hua Jiang, Xinyu Zhang, Baohong Zhang, Huifang Zong, Tao Sun, Ding Kai, Jiaxian Wang
Publikováno v:
Engineering in Life Sciences. 17:801-808
To engineer a host cell line that produces defucosylated mAbs with superior antibody-dependent cellular cytotoxicity, we disrupted α-1, 6 fucosyltransferase (FUT8) gene in CHO-S (CHO is Chinese hamster ovary) cells by clustered regularly interspaced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b1e36516ff119252171c462a6e1ff75
https://doi.org/10.1002/elsc.201600255
https://doi.org/10.1002/elsc.201600255
Autor:
Shi Siwei, Yueqing Xie, Cedric Cagliero, Hua Jiang, Jianwei Zhu, Huanhuan Chen, Chencen Zhu, Han Luo, Junsheng Chen, Lei Feng, Zhang Lei, Menglin Zhao, Ninghuan Li, Xiaoyi Yang, Huili Lu
Publikováno v:
Applied Microbiology and Biotechnology. 101:5267-5278
It has been documented that the purification of inclusion bodies from Escherichia coli by size exclusion chromatography (SEC) may benefit subsequent refolding and recovery of recombinant proteins. However, loading volume and the high cost of the colu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec595c90fc9758df185246c21c428464
https://doi.org/10.1007/s00253-017-8265-x
https://doi.org/10.1007/s00253-017-8265-x
Autor:
Xiaoli, Weng, Christopher H, Bohrer, Kelsey, Bettridge, Arvin Cesar, Lagda, Cedric, Cagliero, Ding Jun, Jin, Jie, Xiao
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(40)
Recent studies have shown that RNA polymerase (RNAP) is organized into distinct clusters in Escherichia coli and Bacillus subtilis cells. Spatially organized molecular components in prokaryotic systems imply compartmentalization without the use of me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::34da58646a625dee8a499c8064d8b800
https://pubmed.ncbi.nlm.nih.gov/31527272
https://pubmed.ncbi.nlm.nih.gov/31527272
Autor:
Huili Lu, Mingyuan Wu, Hua Jiang, Ninghuan Li, Tianyuan Sun, Tong Lin, Yueqing Xie, Cedric Cagliero, Shuai Hao, Meiqi Zhao, Mengxiao Zhang, Hui Yang, Hao Ye, Jianwei Zhu, Manyu Luo
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 112, Iss, Pp-(2019)
Recombinant human interleukin-15 (IL-15) is a potent cancer immunotherapeutic candidate due to its excellent immune stimulating effects. Previous work demonstrated that IL-15 appeared with short half-life in circulation system, while the complex with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb6f83a8e52d7b8bca874ee9d32ab52
http://www.sciencedirect.com/science/article/pii/S0753332219302896
http://www.sciencedirect.com/science/article/pii/S0753332219302896
Autor:
Zhe Sun, Yan Ning Zhou, Cedric Cagliero, William F. Heinz, Jerome Izard, Ding Jun Jin, Thomas D. Schneider, Chen Y
Publikováno v:
Nucleic acids research. 47(8)
RNA polymerase (RNAP), the transcription machinery, shows dynamic binding across the genomic DNA under different growth conditions. The genomic features that selectively redistribute the limited RNAP molecules to dictate genome-wide transcription in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f1115684fd72048fe79fd8b0a91acf
https://pubmed.ncbi.nlm.nih.gov/30843055
https://pubmed.ncbi.nlm.nih.gov/30843055
Autor:
Zixiu Du, Manyu Luo, Mengxiao Zhang, Meiqi Zhao, Ying Zheng, Huili Lu, Jianwei Zhu, Yunsheng Yuan, Hua Jiang, Yueqing Xie, Cedric Cagliero, Hui Yang
Publikováno v:
Applied microbiology and biotechnology. 103(8)
Antigen-binding fragments (Fabs) are an important part of monoclonal antibody (mAb) therapeutics and can be cost-effectively produced using an Escherichia coli (E. coli) expression system. However, Fabs tend to form undesirable aggregates when expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f534f8f1b3867bc989514d8e07821162
https://pubmed.ncbi.nlm.nih.gov/30887174
https://pubmed.ncbi.nlm.nih.gov/30887174
Autor:
Yueqing Xie, Cedric Cagliero, Yang Gao, Ziyan Wang, Jianwei Zhu, Huili Lu, Manyu Luo, Hua Jiang
Publikováno v:
Bio Protoc
In comparison with full-length IgGs, antigen binding fragments (Fabs) are smaller in size and do not require the complexed post-translational modification. Therefore, Fab can be cost-effectively produced using an Escherichia coli (E. coli) expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d6d85af83fa53a306fdb7e6112831a8
https://doi.org/10.21769/bioprotoc.3370
https://doi.org/10.21769/bioprotoc.3370