Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Cedric Belair"'
Autor:
James R. Occean, Na Yang, Yan Sun, Marshall S. Dawkins, Rachel Munk, Cedric Belair, Showkat Dar, Carlos Anerillas, Lin Wang, Changyou Shi, Christopher Dunn, Michel Bernier, Nathan L. Price, Julie S. Kim, Chang-Yi Cui, Jinshui Fan, Moitrayee Bhattacharyya, Supriyo De, Manolis Maragkakis, Rafael de Cabo, Simone Sidoli, Payel Sen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract DNA hydroxymethylation (5hmC), the most abundant oxidative derivative of DNA methylation, is typically enriched at enhancers and gene bodies of transcriptionally active and tissue-specific genes. Although aberrant genomic 5hmC has been impli
Externí odkaz:
https://doaj.org/article/afa1a93ab0c44eaca0dfd46fe91a1ae3
Autor:
Matthew J. Payea, Showkat A. Dar, Carlos Anerillas, Jennifer L. Martindale, Cedric Belair, Rachel Munk, Sulochan Malla, Jinshui Fan, Yulan Piao, Xiaoling Yang, Abid Rehman, Nirad Banskota, Kotb Abdelmohsen, Myriam Gorospe, Manolis Maragkakis
Senescence is a state of indefinite cell cycle arrest associated with aging, cancer, and age-related diseases. Here, using label-based mass spectrometry, ribosome profiling and nanopore direct RNA sequencing, we explore the coordinated interaction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5eec71b1d961b5eaec8e316241049089
https://doi.org/10.1101/2023.04.12.536613
https://doi.org/10.1101/2023.04.12.536613
Autor:
James R. Occean, Na Yang, Yan Sun, Marshall S. Dawkins, Rachel Munk, Cedric Belair, Showkat Dar, Carlos Anerillas, Lin Wang, Changyou Shi, Christopher Dunn, Michel Bernier, Nathan L. Price, Julie S. Kim, Chang-Yi Cui, Jinshui Fan, Moitrayee Bhattacharyya, Supriyo De, Manolis Maragkakis, Rafael deCabo, Simone Sidoli, Payel Sen
Publikováno v:
bioRxiv
DNA hydroxymethylation (5hmC) is the most abundant oxidative derivative of DNA methylation (5mC) and is typically enriched at enhancers and gene bodies of transcriptionally active and tissue-specific genes. Although aberrant genomic 5hmC has been imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e7cbcf521a134df304647a81cc628d
https://doi.org/10.1101/2023.02.15.528714
https://doi.org/10.1101/2023.02.15.528714
Autor:
Sahba Seddighi, Yue A. Qi, Anna-Leigh Brown, Oscar G. Wilkins, Colleen Bereda, Cedric Belair, Yongjie Zhang, Mercedes Prudencio, Matthew J Keuss, Aditya Khandeshi, Sarah Pickles, Sarah E. Hill, James Hawrot, Daniel M. Ramos, Hebao Yuan, Jessica Roberts, Erika Kelmer Sacramento, Syed I. Shah, Mike A. Nalls, Jenn Colon-Mercado, Joel F. Reyes, Veronica H. Ryan, Matthew P. Nelson, Casey Cook, Ziyi Li, Laurel Screven, Justin Y Kwan, Anantharaman Shantaraman, Lingyan Ping, Yuka Koike, Björn Oskarsson, Nathan Staff, Duc M. Duong, Aisha Ahmed, Maria Secrier, Jerneg Ule, Steven Jacobson, Jonathan Rohrer, Andrea Malaspina, Jonathan D. Glass, Alessandro Ori, Nicholas T. Seyfried, Manolis Maragkakis, Leonard Petrucelli, Pietro Fratta, Michael E. Ward
Publikováno v:
bioRxiv
Functional loss of TDP-43, an RNA-binding protein genetically and pathologically linked to ALS and FTD, leads to inclusion of cryptic exons in hundreds of transcripts during disease. Cryptic exons can promote degradation of affected transcripts, dele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52de4bfdb559430326ffc82718aa6b2a
https://europepmc.org/articles/PMC9900763/
https://europepmc.org/articles/PMC9900763/
Publikováno v:
Journal of Cell Biology. 218:2564-2582
A defining feature of embryonic stem cells (ESCs) is the ability to differentiate into all three germ layers. Pluripotency is maintained in part by a unique transcription network that maintains expression of pluripotency-specific transcription factor
Publikováno v:
Chem Rev
Numerous surveillance pathways sculpt eukaryotic transcriptomes by degrading unneeded, defective and potentially harmful noncoding RNAs (ncRNAs). Because aberrant and excess ncRNAs are largely degraded by exoribonucleases, a key characteristic of the
Publikováno v:
Clinical Microbiology and Infection. 15(9):806-812
Chronic infection by Helicobacter pylori is a major risk factor for gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. H. pylori possesses a set of virulence factors, including the CagA effector, which interferes with intracellula
Publikováno v:
Scopus-Elsevier
Loop-loop interactions mediate the recognition between RNA hairpins leading to the formation of so-called kissing complexes. Both the size and the sequence of the loop are critical for ensuring stable interaction. Using in vitro selection we have cha
Autor:
Cathy Staedel, Jessica Baud, Jörg Vogel, Fabien Darfeuille, Cedric Belair, Cynthia M. Sharma, Sandrine Chabas
Publikováno v:
Silence
Silence, 2011, 2 (1), pp.7. ⟨10.1186/1758-907X-2-7⟩
Silence, BioMed Central, 2011, 2 (1), pp.7. ⟨10.1186/1758-907X-2-7⟩
Silence, 2011, 2 (1), pp.7. ⟨10.1186/1758-907X-2-7⟩
Silence, BioMed Central, 2011, 2 (1), pp.7. ⟨10.1186/1758-907X-2-7⟩
Background MicroRNAs, post-transcriptional regulators of eukaryotic gene expression, are implicated in host defense against pathogens. Viruses and bacteria have evolved strategies that suppress microRNA functions, resulting in a sustainable infection