Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Cedric, Bardy"'
Autor:
Mark van den Hurk, Shong Lau, Maria C. Marchetto, Jerome Mertens, Shani Stern, Olga Corti, Alexis Brice, Beate Winner, Jürgen Winkler, Fred H. Gage, Cedric Bardy
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-18 (2022)
Abstract Complex genetic predispositions accelerate the chronic degeneration of midbrain substantia nigra neurons in Parkinson’s disease (PD). Deciphering the human molecular makeup of PD pathophysiology can guide the discovery of therapeutics to s
Externí odkaz:
https://doaj.org/article/14683e153a4e4a20901fa0656fbb2213
Autor:
Shani Stern, Shong Lau, Andreea Manole, Idan Rosh, Menachem Mendel Percia, Ran Ben Ezer, Maxim N. Shokhirev, Fan Qiu, Simon Schafer, Abed AlFatah Mansour, Kile P. Mangan, Tchelet Stern, Polina Ofer, Yam Stern, Ana Paula Diniz Mendes, Jose Djamus, Lynne Randolph Moore, Ritu Nayak, Sapir Havusha Laufer, Aidan Aicher, Amanda Rhee, Thomas L. Wong, Thao Nguyen, Sara B. Linker, Beate Winner, Beatriz C. Freitas, Eugenia Jones, Irit Sagi, Cedric Bardy, Alexis Brice, Juergen Winkler, Maria C. Marchetto, Fred H. Gage
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-16 (2022)
Abstract Several mutations that cause Parkinson’s disease (PD) have been identified over the past decade. These account for 15–25% of PD cases; the rest of the cases are considered sporadic. Currently, it is accepted that PD is not a single monol
Externí odkaz:
https://doaj.org/article/2fa050a5687248eaa0da9d23e96a5eb4
Autor:
Michael Zabolocki, Kasandra McCormack, Mark van den Hurk, Bridget Milky, Andrew P. Shoubridge, Robert Adams, Jenne Tran, Anita Mahadevan-Jansen, Philipp Reineck, Jacob Thomas, Mark R. Hutchinson, Carmen K. H. Mak, Adam Añonuevo, Leon H. Chew, Adam J. Hirst, Vivian M. Lee, Erin Knock, Cedric Bardy
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Current media for neuronal cell and organoid cultures are suboptimal for functional imaging and optogenetics experiments, owing to phototoxicity and unphysiological performance. Here the authors formulate an optimised neuronal medium to support live
Externí odkaz:
https://doaj.org/article/015ec3ef1ee04a14934cb7a0fabc0fe7
Autor:
Giovanna O. Nogueira, Patricia P. Garcez, Cedric Bardy, Mark O. Cunningham, Adriano Sebollela
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/fa05b6bffe7f4ce086333a62b5c8f484
Autor:
Lisa M Ebert, Wenbo Yu, Tessa Gargett, John Toubia, Paris M Kollis, Melinda N Tea, Brenton W Ebert, Cedric Bardy, Mark van den Hurk, Claudine S Bonder, Jim Manavis, Kathleen S Ensbey, Mariana Oksdath Mansilla, Kaitlin G Scheer, Sally L Perrin, Rebecca J Ormsby, Santosh Poonnoose, Barbara Koszyca, Stuart M Pitson, Bryan W Day, Guillermo A Gomez, Michael P Brown
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 10, Pp n/a-n/a (2020)
Abstract Objectives Targeted immunotherapies such as chimeric antigen receptor (CAR)‐T cells are emerging as attractive treatment options for glioblastoma, but rely on identification of a suitable tumor antigen. We validated a new target antigen fo
Externí odkaz:
https://doaj.org/article/d95e2e808e74470a9794a5b6b9f9e770
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Externí odkaz:
https://doaj.org/article/692ab9b81ce543c49f3d8af6b8529e75
Autor:
Mariana Oksdath, Sally L. Perrin, Cedric Bardy, Emily F. Hilder, Cole A. DeForest, R. Dario Arrua, Guillermo A. Gomez
Publikováno v:
APL Bioengineering, Vol 2, Iss 4, Pp 041501-041501-19 (2018)
Stem cell-derived brain organoids provide a powerful platform for systematic studies of tissue functional architecture and the development of personalized therapies. Here, we review key advances at the interface of soft matter and stem cell biology o
Externí odkaz:
https://doaj.org/article/dc23ad1d8a054c39b392371be4b9b762
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
The human brain is composed of a complex assembly of about 171 billion heterogeneous cellular units (86 billion neurons and 85 billion non-neuronal glia cells). A comprehensive description of brain cells is necessary to understand the nervous system
Externí odkaz:
https://doaj.org/article/6feefcc61b4149bdab87ce80ce6e81b1
Publikováno v:
Trends in cancer.
Glioblastoma (GBM) remains the most lethal primary brain cancer largely due to recurrence of treatment-resistant disease. Current therapies are ultimately ineffective as GBM tumour cells adapt their identity to escape treatment. Recent advances in si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7317d7932f79ca76b0dbf434c901893a
https://pubmed.ncbi.nlm.nih.gov/36460606
https://pubmed.ncbi.nlm.nih.gov/36460606
Autor:
Dmitry Kobak, Cathryn R. Cadwell, Shreejoy J. Tripathy, Cedric Bardy, Kristen Hadley, Marcela Lipovsek
Publikováno v:
J Neurosci
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 41, iss 5
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 41, iss 5
Single-cell transcriptomic approaches are revolutionizing neuroscience. Integrating this wealth of data with morphology and physiology, for the comprehensive study of neuronal biology, requires multiplexing gene expression data with complementary tec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f74057d06f3d989fc1f5e9b3528ab4
https://doi.org/10.1523/jneurosci.1653-20.2020
https://doi.org/10.1523/jneurosci.1653-20.2020