Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Cecily C Midkiff"'
Autor:
Giorgio Zenere, Chengxiang Wu, Cecily C Midkiff, Nathan M Johnson, Christopher P Grice, William C Wimley, Amitinder Kaur, Stephen E Braun
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0293990 (2024)
Chimeric antigen receptor (CAR)-T cells have demonstrated clinical potential, but current receptors still need improvements to be successful against chronic HIV infection. In this study, we address some requirements of CAR motifs for strong surface e
Externí odkaz:
https://doaj.org/article/e8dbe9a7e70048bfb98b004007c0f038
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-21 (2023)
Abstract Background Lyme neuroborreliosis, caused by the bacterium Borrelia burgdorferi affects both the central and peripheral nervous systems (CNS, PNS). The CNS manifestations, especially at later stages, can mimic/cause many other neurological co
Externí odkaz:
https://doaj.org/article/f13ba1a25a444ba6b9cca4167d60f433
Autor:
Alyssa C Fears, Brandon J Beddingfield, Nicole R Chirichella, Nadia Slisarenko, Stephanie Z Killeen, Rachel K Redmann, Kelly Goff, Skye Spencer, Breanna Picou, Nadia Golden, Cecily C Midkiff, Duane J Bush, Luis M Branco, Matthew L Boisen, Hongmei Gao, David C Montefiori, Robert V Blair, Lara A Doyle-Meyers, Kasi Russell-Lodrigue, Nicholas J Maness, Chad J Roy
Publikováno v:
PLoS Pathogens, Vol 18, Iss 7, p e1010618 (2022)
The novel coronavirus SARS-CoV-2 emerged in late 2019, rapidly reached pandemic status, and has maintained global ubiquity through the emergence of variants of concern. Efforts to develop animal models have mostly fallen short of recapitulating sever
Externí odkaz:
https://doaj.org/article/520e4f07330948dfb9dec099171ac336
Autor:
Patrick J. Madden, Muhammad S. Arif, Mark E. Becker, Michael D. McRaven, Ann M. Carias, Ramon Lorenzo-Redondo, Sixia Xiao, Cecily C. Midkiff, Robert V. Blair, Elizabeth Lake Potter, Laura Martin-Sancho, Alan Dodson, Elena Martinelli, John-Paul M. Todd, Francois J. Villinger, Sumit K. Chanda, Pyone Pyone Aye, Chad J. Roy, Mario Roederer, Mark G. Lewis, Ronald S. Veazey, Thomas J. Hope
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Infection with the novel coronavirus, SARS-CoV-2, results in pneumonia and other respiratory symptoms as well as pathologies at diverse anatomical sites. An outstanding question is whether these diverse pathologies are due to replication of the virus
Externí odkaz:
https://doaj.org/article/74bcab5e177646ac8a31e5c09bd2f86c
Autor:
Fengming Liu, Kun Han, Robert Blair, Kornelia Kenst, Zhongnan Qin, Berin Upcin, Philipp Wörsdörfer, Cecily C. Midkiff, Joseph Mudd, Elizaveta Belyaeva, Nicholas S. Milligan, Tyler D. Rorison, Nicole Wagner, Jochen Bodem, Lars Dölken, Bertal H. Aktas, Richard S. Vander Heide, Xiao-Ming Yin, Jay K. Kolls, Chad J. Roy, Jay Rappaport, Süleyman Ergün, Xuebin Qin
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
SARS-CoV-2 infection can cause fatal inflammatory lung pathology, including thrombosis and increased pulmonary vascular permeability leading to edema and hemorrhage. In addition to the lung, cytokine storm-induced inflammatory cascade also affects ot
Externí odkaz:
https://doaj.org/article/e2de576c347c428db861b40e4ee8c99f
Autor:
Jennifer M. Rudd, Miruthula Tamil Selvan, Shannon Cowan, Yun-Fan Kao, Cecily C. Midkiff, Sai Narayanan, Akhilesh Ramachandran, Jerry W. Ritchey, Craig A. Miller
Publikováno v:
Viruses, Vol 13, Iss 8, p 1550 (2021)
The emergence and ensuing dominance of COVID-19 on the world stage has emphasized the urgency of efficient animal models for the development of therapeutics for and assessment of immune responses to SARS-CoV-2 infection. Shortcomings of current anima
Externí odkaz:
https://doaj.org/article/8d1a27a502104eb086eb223b39ab3264
BackgroundLyme neuroborreliosis, caused by the bacterium Borrelia burgdorferi affects both the central and peripheral nervous systems (CNS, PNS). The CNS manifestations, especially at later stages, can mimic/cause many other neurological conditions i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17f57925775ba2ac29ab998f8f2d537a
https://doi.org/10.1101/2022.08.22.504844
https://doi.org/10.1101/2022.08.22.504844
Autor:
Bertal H. Aktas, Richard S. Vander Heide, Haoran Yang, Cecily C. Midkiff, Kun Han, Zhongnan Qin, Giovanni Piedimonte, Naoki Iwanaga, Jay K. Kolls, Mohammad Afaque Alam, Robert V Blair, Fengming Liu, Xuebin Qin, Franck Mauvais-Jarvis, Süleyman Ergün, Joseph Mudd, Chenxiao Wang, Joshua M Currey, Jibao He, Nicholas J. Maness, Jay Rappaport, Ronald S. Veazey, Ren Mi
Publikováno v:
Theranostics
Rationale: Pulmonary vascular endotheliitis, perivascular inflammation, and immune activation are observed in COVID-19 patients. While the initial SARS-CoV-2 infection mainly infects lung epithelial cells, whether it also infects endothelial cells (E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d96379a8c1dfb606206430c8c8be17
https://doi.org/10.7150/thno.61810
https://doi.org/10.7150/thno.61810
Autor:
Mohammad E. Kabir, Jay K. Kolls, Kellie L. Cutrera, Brandon J. Beddingfield, Alanna Wanek, Kasi E. Russell-Lodrigue, Angela Birnbaum, Mi Ren, Robert V Blair, Xuebin Qin, Naoki Iwanaga, Nadia A. Golden, Kun Han, Tracy Fischer, Fengming Liu, Christopher J. Monjure, Chad J. Roy, Kristin E Chandler, Gabrielle Lehmicke, Lara A. Doyle-Meyers, Jay Rappaport, Zhongnan Qin, Prasun K. Datta, Nicholas J. Maness, Cecily C. Midkiff
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Preclinical mouse models that recapitulate some characteristics of coronavirus disease (COVID-19) will facilitate focused study of pathogenesis and virus–host responses. Human agniotensin-converting enzyme 2 (hACE2) serves as an entry receptor for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2862dc77b48e3a0fb5d5ed9880bb87
https://doi.org/10.1165/rcmb.2020-0354oc
https://doi.org/10.1165/rcmb.2020-0354oc
Autor:
Marissa Fahlberg, Cecily C. Midkiff, Hongmei Gao, Faith Schiro, Breanna Picou, Kasi E. Russell-Lodrigue, Pyone P. Aye, Kelly Goff, Krystle Hensley, Nadia A. Golden, Rudolf P. Bohm, David C. Montefiori, Lara A. Doyle-Meyers, Nicholas J. Maness, Robert V Blair, Scott C. Weaver, Joseph L. Mankowski, Alexandra Melton, Jay Rappaport, Brandon J. Beddingfield, Dawn M. Szeltner, Chad J. Roy, Kristin E Chandler, Skye Spencer, Toni Penney, Jessica A. Plante, James A. Hoxie, Hunter J Melton, Kenneth S. Plante
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010162 (2021)
PLoS Pathogens
PLoS Pathogens
The novel coronavirus SARS-CoV-2, the causative agent of COVID-19 disease, has killed over five million people worldwide as of December 2021 with infections rising again due to the emergence of highly transmissible variants. Animal models that faithf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b536dc280cdba5b5c2b712522c630e74
https://doaj.org/article/a4d62fa7ec5b4fcc9a46c16a5466b091
https://doaj.org/article/a4d62fa7ec5b4fcc9a46c16a5466b091