Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Cecilie L, Bager"'
Autor:
Song Wang, Cecilie L. Bager, Morten A. Karsdal, Dimitrios Chondros, Darin Taverna, Nicholas Willumsen
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract Background Extensive extracellular matrix (ECM) remodeling is a hallmark of metastatic pancreatic ductal adenocarcinoma (mPDA). We investigated fragments of collagen types III (C3M, PRO-C3), VI (PRO-C6), and VIII (C8-C), and versican (VCANM)
Externí odkaz:
https://doaj.org/article/ba7e25ea26134c6bb7ed23c4b9dd9e92
Autor:
Cecilie L. Bager, Morten Karsdal, Asger Bihlet, Christian Thudium, Inger Byrjalsen, Anne C. Bay-Jensen
Publikováno v:
BMC Musculoskeletal Disorders, Vol 20, Iss 1, Pp 1-6 (2019)
Abstract Background Osteoarthritis (OA) leads to joint failure and total joint replacement (TJR, either hip (H) or knee (K)). Worsening of pain and joint space narrowing are believed to be surrogates for joint failure; however, we hypothesize that TJ
Externí odkaz:
https://doaj.org/article/803bd5e56a53428a8643b17a89b19223
Autor:
Nicholas Willumsen, Cecilie L. Bager, Diana J. Leeming, Anne-Christine Bay-Jensen, Morten A. Karsdal
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 4, Pp 271-278 (2017)
Loss of basement membrane (BM) integrity is typically associated with cancer. Nidogen-1 is an essential component of the BM. Nidogen-1 is a substrate for cathepsin-S (CatS) which is released into the tumor microenvironment. Measuring nidogen-1 degrad
Externí odkaz:
https://doaj.org/article/958b88a433ba443fbbbfa33689929015
Autor:
Morten Karsdal, Estrid Høgdall, Claus Christiansen, Jesper Skov Neergaard, Katrine Dragsbæk, Diana J. Leeming, Anne-Christine Bay-Jensen, Henrik B. Hansen, Stephanie N. Kehlet, Nicholas Willumsen, Cecilie L. Bager
Supplementary Figure 1. Serum biomarker levels in relation to time to diagnosis. Biomarker levels were plotted against the elapsed time interval between blood draw and cancer diagnosis. The plots were evaluated using a Spearman test.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::656334cb2077042a0a3b8a223a9cb251
https://doi.org/10.1158/1055-9965.22437562.v1
https://doi.org/10.1158/1055-9965.22437562.v1
Autor:
Morten Karsdal, Estrid Høgdall, Claus Christiansen, Jesper Skov Neergaard, Katrine Dragsbæk, Diana J. Leeming, Anne-Christine Bay-Jensen, Henrik B. Hansen, Stephanie N. Kehlet, Nicholas Willumsen, Cecilie L. Bager
Background: An altered tumor microenvironment is one of the earliest signs of cancer and an important driver of the disease. We have seen previously that biomarkers reflecting tumor microenvironment modifications, such as matrix metalloproteinase (MM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b2a9b0a03895007857f80f7361ddda3
https://doi.org/10.1158/1055-9965.c.6515938.v1
https://doi.org/10.1158/1055-9965.c.6515938.v1
Autor:
Cecilie L. Bager, M. H. Tang, Anne-Christine Bay-Jensen, Søren Brunak, P. Frederiksen, Morten A. Karsdal, Joseph P.M. Blair
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Blair, J P M, Bay-Jensen, A-C, Tang, M H, Frederiksen, P, Bager, C, Karsdal, M & Brunak, S 2020, ' Identification of heterogenous treatment response trajectories to anti-IL6 receptor treatment in rheumatoid arthritis ', Scientific Reports, vol. 10, no. 1, 13975 . https://doi.org/10.1038/s41598-020-70942-x
Scientific Reports
Blair, J P M, Bay-Jensen, A-C, Tang, M H, Frederiksen, P, Bager, C, Karsdal, M & Brunak, S 2020, ' Identification of heterogenous treatment response trajectories to anti-IL6 receptor treatment in rheumatoid arthritis ', Scientific Reports, vol. 10, no. 1, 13975 . https://doi.org/10.1038/s41598-020-70942-x
Rheumatoid arthritis (RA) is a chronic inflammatory disease with fluctuating course of progression. Despite substantial improvement in treatments in recent years, treatment response is still not guaranteed. The aim of this study was to identify varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7db7fd38f21f0b1757774b60f7de0e0
http://link.springer.com/article/10.1038/s41598-020-70942-x
http://link.springer.com/article/10.1038/s41598-020-70942-x
Autor:
Rose C. Christian, Mette Juul Nielsen, Daniel Guldager Kring Rasmussen, Cecilie L. Bager, Diana Julie Leeming, Jacob George, Natasja Stæhr Gudmann, Rambabu Surabattula, Yi Luo, Ida Villesen, Morten A. Karsdal, Signe Holm Nielsen, Samuel Joseph Daniels, Rohit Loomba, Diane E. Shevell, Detlef Schuppan
Publikováno v:
Liver International. 40:736-750
There is an unmet need for high-quality liquid biomarkers that can safely and reproducibly predict the stage of fibrosis and the outcomes of chronic liver disease (CLD). The requirement for such markers has intensified because of the high global prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361170b5f04cbe369e91f477d99f2d0f
https://doi.org/10.1111/liv.14390
https://doi.org/10.1111/liv.14390
Autor:
D.J. Leeming, Nicholas Willumsen, L. Jennings, M.A. Karsdal, Kim Henriksen, Tina Manon-Jensen, Joachim Høg Mortensen, Federica Genovese, S. Holm Nielsen, Daniel Guldager Kring Rasmussen, Alexander L. Reese-Petersen, Jannie M.B. Sand, Cecilie L. Bager, A.-C. Bay-Jensen, Christina Jensen
Publikováno v:
Clinical biochemistry. 97
Objectives There is a need for precision medicine and an unspoken promise of an optimal approach for identification of the right patients for value-based medicine based on big data. However, there may be a misconception that measurement of proteins i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d831073f1ac950fc8479a2417dc8947
https://pubmed.ncbi.nlm.nih.gov/34453894
https://pubmed.ncbi.nlm.nih.gov/34453894
Publikováno v:
Translational Oncology
Translational Oncology, Vol 12, Iss 5, Pp 693-698 (2019)
Translational Oncology, Vol 12, Iss 5, Pp 693-698 (2019)
BACKGROUND: Type VI collagen (COL6) is associated with several pro-tumorigenic events. COL6 is primarily composed of three alpha-chains (a1-a3) forming a specialized microfibrillar network to support tissue architecture. COL6 homeostasis is lost in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e45025927c03e9dab19b71cea9adb7
https://doi.org/10.1016/j.tranon.2019.02.004
https://doi.org/10.1016/j.tranon.2019.02.004
Autor:
Cecilie L. Bager, Morten A. Karsdal, Bidisha Dasgupta, Carrie Brodmerkel, Mark Curran, Nicholas Willumsen, Jannie M.B. Sand, D.J. Leeming, S Holm Nielsen
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 17, Iss, Pp 38-43 (2019)
Biochemistry and Biophysics Reports, Vol 17, Iss, Pp 38-43 (2019)
Objectives: Lysyl oxidase like 2 (LOXL2) is associated with poor prognosis in idiopathic pulmonary disease (IPF) and cancer. We developed an Enzyme-linked immunosorbent assay (ELISA) targeting the LOXL2 neo-epitope generated through the release of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0546bda8f6758ecfa70211c7cf338d5
https://doi.org/10.1016/j.bbrep.2018.11.002
https://doi.org/10.1016/j.bbrep.2018.11.002