Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Cecilie Abildgaard"'
Autor:
Lars Henrik Jensen, Silvia Regina Rogatto, Jan Lindebjerg, Birgitte Havelund, Cecilie Abildgaard, Luisa Matos do Canto, Chris Vagn-Hansen, Claus Dam, Søren Rafaelsen, Torben Frøstrup Hansen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-9 (2023)
Abstract Background Patients with colorectal metastatic disease have a poor prognosis, limited therapeutic options, and frequent development of resistance. Strategies based on tumor-derived organoids are a powerful tool to assess drug sensitivity at
Externí odkaz:
https://doaj.org/article/c6f05e4f0fc248729356b947f9616dde
Autor:
Robson Francisco Carvalho, Luisa Matos do Canto, Cecilie Abildgaard, Mads Malik Aagaard, Monica Søgaard Tronhjem, Marianne Waldstrøm, Lars Henrik Jensen, Karina Dahl Steffensen, Silvia Regina Rogatto
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background Serous ovarian carcinoma is the most frequent histological subgroup of ovarian cancer and the leading cause of death among gynecologic tumors. The tumor microenvironment and cancer-associated fibroblasts (CAFs) have a critical rol
Externí odkaz:
https://doaj.org/article/e817f5f9f71a4678bc3b43b9d4088b79
Autor:
Cecilie Abildgaard, Salvatore Rizza, Helle Christiansen, Steffen Schmidt, Christina Dahl, Ahmad Abdul-Al, Annette Christensen, Giuseppe Filomeni, Per Guldberg
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The prognosis of metastatic melanoma remains poor due to de novo or acquired resistance to immune and targeted therapies. Previous studies have shown that melanoma cells have perturbed metabolism and that cellular metabolic pathways represen
Externí odkaz:
https://doaj.org/article/1b24ea4a0dc64c8fbd2d5e8ec70458cd
Autor:
Isabella Maria Dias Payão Ortiz, Mateus Camargo Barros-Filho, Mariana Bisarro dos Reis, Caroline Moraes Beltrami, Fabio Albuquerque Marchi, Hellen Kuasne, Luísa Matos do Canto, Julia Bette Homem de Mello, Cecilie Abildgaard, Clóvis Antônio Lopes Pinto, Luiz Paulo Kowalski, Silvia Regina Rogatto
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-13 (2018)
Abstract Background DNA methylation in miRNA genes has been reported as a mechanism that may cause dysregulation of mature miRNAs and consequently impact the gene expression. This mechanism is largely unstudied in papillary thyroid carcinomas (PTC).
Externí odkaz:
https://doaj.org/article/a1e9f36f064e40fa86aa2ad50e93023e
Autor:
Cecilie Abildgaard, Luisa Matos do Canto, Cláudia Aparecida Rainho, Fabio Albuquerque Marchi, Naiade Calanca, Marianne Waldstrøm, Karina Dahl Steffensen, Silvia Regina Rogatto
Publikováno v:
Cancers, Vol 14, Iss 7, p 1664 (2022)
Genetic and epigenetic changes contribute to intratumor heterogeneity and chemotherapy resistance in several tumor types. LncRNAs have been implicated, directly or indirectly, in the epigenetic regulation of gene expression. We investigated lncRNAs t
Externí odkaz:
https://doaj.org/article/39852c563a194d14867488d166fbf06a
Publikováno v:
Frontiers in Oncology, Vol 9 (2020)
Ovarian cancer (OC) accounts for more than 150,000 deaths worldwide every year. Patients are often diagnosed at an advanced stage with metastatic dissemination. Although platinum- and taxane-based chemotherapies are effective treatment options, they
Externí odkaz:
https://doaj.org/article/e32a5616415e48eba912a15f709ceca6
The Interplay between Long Noncoding RNAs and Proteins of the Epigenetic Machinery in Ovarian Cancer
Publikováno v:
Cancers, Vol 12, Iss 9, p 2701 (2020)
Comprehensive large-scale sequencing and bioinformatics analyses have uncovered a myriad of cancer-associated long noncoding RNAs (lncRNAs). Aberrant expression of lncRNAs is associated with epigenetic reprogramming during tumor development and progr
Externí odkaz:
https://doaj.org/article/766da9f35ebf4e28a5a6c6b9539b79ba
Autor:
Soeren Rafael Rafaelsen, Birgitte Mayland Havelund, Anders Jakobsen, Silvia Regina Rogatto, Luisa Matos do Canto, Chris Aksel Vagn-Hansen, Torben Hansen, Lars Henrik Jensen, Claus Dam, Cecilie Abildgaard, Jan Lindebjerg
Publikováno v:
Jensen, L H, Jakobsen, A K M, Havelund, B M, Abildgaard, C, Vagn-Hansen, C, Dam, C, Lindebjerg, J, Canto, L M, Rogatto, S R, Rafaelsen, S R & Hansen, T 2021, ' Functional precision medicine in colorectal cancer based on patient-derived tumoroids and in-vitro sensitivity drug testing. ', Journal of Clinical Oncology, vol. 39, no. Suppl. 15 . https://doi.org/10.1200/JCO.2021.39.15suppl.e15567
e15567 Background: Precision oncology based on in-vitro, functional assays has potential advantages compared to the much more common molecular approach, but the clinical benefit is unknown. We here report the results from the largest prospective inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70456c9d846806dce26059f9a34234f6
https://portal.findresearcher.sdu.dk/da/publications/251ff525-5cb1-41ec-962a-bd4e549e29cf
https://portal.findresearcher.sdu.dk/da/publications/251ff525-5cb1-41ec-962a-bd4e549e29cf
The Interplay between Long Noncoding RNAs and Proteins of the Epigenetic Machinery in Ovarian Cancer
Publikováno v:
Cancers
Cancers, Vol 12, Iss 2701, p 2701 (2020)
Calanca, N, Abildgaard, C, Rainho, C A & Rogatto, S R 2020, ' The interplay between long noncoding rnas and proteins of the epigenetic machinery in ovarian cancer ', Cancers, vol. 12, no. 9, 2701 . https://doi.org/10.3390/cancers12092701
Cancers, Vol 12, Iss 2701, p 2701 (2020)
Calanca, N, Abildgaard, C, Rainho, C A & Rogatto, S R 2020, ' The interplay between long noncoding rnas and proteins of the epigenetic machinery in ovarian cancer ', Cancers, vol. 12, no. 9, 2701 . https://doi.org/10.3390/cancers12092701
Simple Summary Epithelial ovarian cancer is an aggressive disease associated with relapse, resistance to chemotherapy, and high mortality rates. Recent discoveries have pointed out that long noncoding RNAs (lncRNAs) are potential biomarkers or therap
Publikováno v:
Oncotarget
// Cecilie Abildgaard 1 , Christina Dahl 1 , Ahmad Abdul-Al 1 , Annette Christensen 1 and Per Guldberg 1 1 Danish Cancer Society Research Center, Copenhagen, Denmark Correspondence to: Per Guldberg, email: perg@cancer.dk Keywords: melanoma, cancer me