Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Cecilia Williams"'
Autor:
Christian Sommerauer, Carlos J Gallardo-Dodd, Christina Savva, Linnea Hases, Madeleine Birgersson, Rajitha Indukuri, Joanne X Shen, Pablo Carravilla, Keyi Geng, Jonas Nørskov Søndergaard, Clàudia Ferrer-Aumatell, Grégoire Mercier, Erdinc Sezgin, Marion Korach-André, Carl Petersson, Hannes Hagström, Volker M Lauschke, Amena Archer, Cecilia Williams, Claudia Kutter
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 4, Pp 374-402 (2024)
Abstract Sex-based differences in obesity-related hepatic malignancies suggest the protective roles of estrogen. Using a preclinical model, we dissected estrogen receptor (ER) isoform-driven molecular responses in high-fat diet (HFD)-induced liver di
Externí odkaz:
https://doaj.org/article/ee239cfd60044f218b6abfe27eac0000
Publikováno v:
Environment International, Vol 190, Iss , Pp 108937- (2024)
Human adenovirus (HAdV) type F41 has been identified as a possible cause of the non-A-to-E hepatitis outbreak. This study uses wastewater monitoring to track HAdV F40 and F41, supporting clinical investigations and providing insights into the pathoge
Externí odkaz:
https://doaj.org/article/a03374dddfb7499bac6de46ef651e0cd
Autor:
Madeleine Birgersson, Rajitha Indukuri, Linnéa Lindquist, Lina Stepanauskaite, Qing Luo, Qiaolin Deng, Amena Archer, Cecilia Williams
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-23 (2023)
Abstract Background Estrogen receptor beta (ERβ, Esr2) plays a pivotal role in folliculogenesis and ovulation, yet its exact mechanism of action is mainly uncharacterized. Results We here performed ERβ ChIP-sequencing of mouse ovaries followed by c
Externí odkaz:
https://doaj.org/article/727a9789e99f4472ba2342400bbc6e90
Autor:
Linnea Hases, Lina Stepanauskaite, Madeleine Birgersson, Nele Brusselaers, Ina Schuppe-Koistinen, Amena Archer, Lars Engstrand, Cecilia Williams
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
A metagenomic analysis reveals that male and female mice exhibit sex-dependent responses to a high-fat diet (HFD), and that estrogenic ligands can attenuate certain aspects of HFDinduced dysbiosis.
Externí odkaz:
https://doaj.org/article/3a1403a1393f4fdbaf958e75f5ebbdec
Autor:
Dandan Song, Huan He, Rajitha Indukuri, Zhiqiang Huang, Lina Stepanauskaite, Indranil Sinha, Lars-Arne Haldosén, Chunyan Zhao, Cecilia Williams
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
The two estrogen receptors ERα and ERβ are nuclear receptors that bind estrogen (E2) and function as ligand-inducible transcription factors. They are homologues and can form dimers with each other and bind to the same estrogen-response element moti
Externí odkaz:
https://doaj.org/article/738a38fd4263449b9f8981899e871eb4
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/8bc030a7c6864ba49bc9c1a3153c15eb
Autor:
Fahmi Mesmar, Bingbing Dai, Ahmed Ibrahim, Linnea Hases, Mohammed Hakim Jafferali, Jithesh Jose Augustine, Sebastian DiLorenzo, Ya'an Kang, Yang Zhao, Jing Wang, Michael Kim, Chin‐Yo Lin, Anders Berkenstam, Jason Fleming, Cecilia Williams
Publikováno v:
Cancer Medicine, Vol 8, Iss 18, Pp 7705-7719 (2019)
Abstract Despite advances in cancer therapeutics, pancreatic cancer remains difficult to treat and often develops resistance to chemotherapies. We have evaluated a bioavailable genistein analogue, AXP107‐11 which has completed phase Ib clinical tri
Externí odkaz:
https://doaj.org/article/900afa4941d14028b0d39be55bc5e75d
Autor:
Daoshan Zheng, Justyna Trynda, Cecilia Williams, Jeremy A. Vold, Justin H. Nguyen, Denise M. Harnois, Sanjay P. Bagaria, Sarah A. McLaughlin, Zhaoyu Li
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background Sex differences in the incidences of cancers become a critical issue in both cancer research and the development of precision medicine. However, details in these differences have not been well reported. We provide a comprehensive
Externí odkaz:
https://doaj.org/article/ca47acea000a44ec94e62c065a18e099
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Inflammation is a primary component of both initiation and promotion of colorectal cancer (CRC). Cytokines secreted by macrophages, including tumor necrosis factor alpha (TNFα), activates the pro-survival transcription factor complex NFκB. The prec
Externí odkaz:
https://doaj.org/article/f6d5919d601c402bb804aa80e389c609
Autor:
Yirui Cheng, Xiangyun Qu, Zhaonan Dong, Qingyu Zeng, Xueqing Ma, Yunli Jia, Ruochen Li, Xiaoxu Jiang, Cecilia Williams, Tao Wang, Weiliang Xia
Publikováno v:
PeerJ, Vol 8, p e9434 (2020)
Background Exosomes are nano-sized extracellular vesicles containing different biomolecules such as proteins and microRNAs (miRNAs) that mediate intercellular communication. Recently, numerous studies have reported the important functions of exosomal
Externí odkaz:
https://doaj.org/article/6c6bfdba8f664737ab8121090007297d